Emma Williams1,2, Theodore Dassios1,3, Niamh O'Reilly1, Alison Walsh1, Anne Greenough4,5,6. 1. Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK. 2. The Asthma UK Centre for Allergic Mechanisms in Asthma, King's College London, London, UK. 3. Neonatal Intensive Care Unit, King's College Hospital NHS Foundation Trust, London, UK. 4. Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK. anne.greenough@kcl.ac.uk. 5. The Asthma UK Centre for Allergic Mechanisms in Asthma, King's College London, London, UK. anne.greenough@kcl.ac.uk. 6. NIHR Biomedical Research Centre based at Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK. anne.greenough@kcl.ac.uk.
Abstract
OBJECTIVE: To assess whether end-tidal capnography (EtCO2) monitoring reduced the magnitude of difference in carbon dioxide (CO2) levels and the number of blood gases in ventilated infants. STUDY DESIGN: A case-control study of a prospective cohort (n = 36) with capnography monitoring and matched historical controls (n = 36). RESULT: The infants had a median gestational age of 31.6 weeks. A reduction in the highest CO2 level on day 1 after birth was observed after the introduction of EtCO2 monitoring (p = 0.043). There was also a reduction in the magnitude of difference in CO2 levels on days 1 (p = 0.002) and 4 (p = 0.049) after birth. There was no significant difference in the number of blood gases. CONCLUSION: Continuous end-tidal capnography monitoring in ventilated infants was associated with a reduction in the degree of the magnitude of difference in CO2 levels and highest level of CO2 on the first day after birth.
OBJECTIVE: To assess whether end-tidal capnography (EtCO2) monitoring reduced the magnitude of difference in carbon dioxide (CO2) levels and the number of blood gases in ventilated infants. STUDY DESIGN: A case-control study of a prospective cohort (n = 36) with capnography monitoring and matched historical controls (n = 36). RESULT: The infants had a median gestational age of 31.6 weeks. A reduction in the highest CO2 level on day 1 after birth was observed after the introduction of EtCO2 monitoring (p = 0.043). There was also a reduction in the magnitude of difference in CO2 levels on days 1 (p = 0.002) and 4 (p = 0.049) after birth. There was no significant difference in the number of blood gases. CONCLUSION: Continuous end-tidal capnography monitoring in ventilated infants was associated with a reduction in the degree of the magnitude of difference in CO2 levels and highest level of CO2 on the first day after birth.