Literature DB >> 33644706

The S1A protease family members CG10764 and CG4793 regulate cellular immunity in Drosophila.

Pooja Kr1, Jonathan Lee1, Nathan T Mortimer1.   

Abstract

In nature, Drosophila melanogaster larvae are infected by parasitoid wasps and mount a cellular immune response to this infection. Several conserved signaling pathways have been implicated in coordinating this response, however our understanding of the integration and regulation of these pathways is incomplete. Members of the S1A serine protease family have been previously linked to immune functions, and our findings suggest roles for two S1A family members, CG10764 and CG4793 in the cellular immune response to parasitoid infection. Copyright:
© 2021 by the authors.

Entities:  

Year:  2021        PMID： 33644706      PMCID： PMC7900826          DOI： 10.17912/micropub.biology.000370

Source DB:  PubMed          Journal:  MicroPubl Biol        ISSN： 2578-9430


  26 in total

1.  Activation of Drosophila Toll during fungal infection by a blood serine protease.

Authors:  Petros Ligoxygakis; Nadège Pelte; Jules A Hoffmann; Jean-Marc Reichhart
Journal:  Science       Date:  2002-07-05       Impact factor: 47.728

2.  A directed miniscreen for genes involved in the Drosophila anti-parasitoid immune response.

Authors:  Laura Howell; Christopher J Sampson; Miguel J Xavier; Ekin Bolukbasi; Margarete M S Heck; Michael J Williams
Journal:  Immunogenetics       Date:  2011-09-27       Impact factor: 2.846

3.  Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways.

Authors:  H Luo; P Rose; D Barber; W P Hanratty; S Lee; T M Roberts; A D D'Andrea; C R Dearolf
Journal:  Mol Cell Biol       Date:  1997-03       Impact factor: 4.272

4.  A single modular serine protease integrates signals from pattern-recognition receptors upstream of the Drosophila Toll pathway.

Authors:  Nicolas Buchon; Mickael Poidevin; Hyun-Mi Kwon; Aurélien Guillou; Valentin Sottas; Bok-Luel Lee; Bruno Lemaitre
Journal:  Proc Natl Acad Sci U S A       Date:  2009-07-09       Impact factor: 11.205

5.  Insect immunity: early events in the encapsulation process of parasitoid (Leptopilina boulardi) eggs in resistant and susceptible strains of Drosophila.

Authors:  J Russo; S Dupas; F Frey; Y Carton; M Brehelin
Journal:  Parasitology       Date:  1996-01       Impact factor: 3.234

6.  The Drosophila Tumorous-lethal hematopoietic oncogene is a dominant mutation in the hopscotch locus.

Authors:  W P Hanratty; C R Dearolf
Journal:  Mol Gen Genet       Date:  1993-04

7.  Gα73B is a downstream effector of JAK/STAT signalling and a regulator of Rho1 in Drosophila haematopoiesis.

Authors:  Nina Bausek; Martin P Zeidler
Journal:  J Cell Sci       Date:  2013-10-25       Impact factor: 5.285

8.  Parasitoid wasp virulence: A window into fly immunity.

Authors:  Nathan T Mortimer
Journal:  Fly (Austin)       Date:  2013-10-02       Impact factor: 2.160

9.  Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects.

Authors:  D A Harrison; R Binari; T S Nahreini; M Gilman; N Perrimon
Journal:  EMBO J       Date:  1995-06-15       Impact factor: 11.598

10.  The serine protease homolog spheroide is involved in sensing of pathogenic Gram-positive bacteria.

Authors:  Jelena Patrnogic; Vincent Leclerc
Journal:  PLoS One       Date:  2017-12-06       Impact factor: 3.240
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  1 in total

1.  Meta-Analysis of Immune Induced Gene Expression Changes in Diverse Drosophila melanogaster Innate Immune Responses.

Authors:  Ashley L Waring; Joshua Hill; Brooke M Allen; Nicholas M Bretz; Nguyen Le; Pooja Kr; Dakota Fuss; Nathan T Mortimer
Journal:  Insects       Date:  2022-05-23       Impact factor: 3.139
  1 in total

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