| Literature DB >> 33643932 |
Shamila D Alipoor1, Esmaeil Mortaz2,3, Hamidreza Jamaati4, Payam Tabarsi2, Hasan Bayram5, Mohammad Varahram6, Ian M Adcock7,8.
Abstract
In late December 2019, a vtiral pneumonia with an unknown agent was reported in Wuhan, China. A novel coronavirus was identified as the causative agent. Because of the human-to-human transmission and rapid spread; coronavirus disease 2019 (COVID-19) has rapidly increased to an epidemic scale and poses a severe threat to human health; it has been declared a public health emergency of international concern (PHEIC) by the World Health Organization (WHO). This review aims to summarize the recent research progress of COVID-19 molecular features and immunopathogenesis to provide a reference for further research in prevention and treatment of SARS coronavirus2 (SARS-CoV-2) infection based on the knowledge from researches on SARS-CoV and Middle East respiratory syndrome-related coronavirus (MERS-CoV).Entities:
Keywords: ACE2; COVID-19; IL-6; IL-8; cytokines
Mesh:
Substances:
Year: 2021 PMID: 33643932 PMCID: PMC7904902 DOI: 10.3389/fcimb.2021.563085
Source DB: PubMed Journal: Front Cell Infect Microbiol ISSN: 2235-2988 Impact factor: 5.293