Literature DB >> 33643900

Regulatory Effects of Circular RNAs on Host Genes in Human Cancer.

Xiong Wang1, Huijun Li1, Yanjun Lu1, Liming Cheng1.   

Abstract

Circular RNAs (circRNAs) are a class of single-stranded, covalent closed-loop RNAs with tissue-/development-specific expression patterns. circRNAs are stable and play oncogenic or tumor suppressive roles in various aspects of cancer, including tumorigenesis, proliferation, apoptosis, metastasis, invasion, chemo-therapeutic resistance, and prognosis. circRNAs act as miRNA/protein sponges, protein scaffold, or template for translation. Increasing evidence shows circRNAs contribute to cancer progression via modulating the expression or function of their host genes. In this review, we summarize the latest progress in the regulation of host genes by circRNAs in human cancer. The works on circRNAs mediated regulation of host genes enhance us to understand the interaction between circRNAs and their host genes in human cancer.
Copyright © 2021 Wang, Li, Lu and Cheng.

Entities:  

Keywords:  cancer; circRNA; host gene; miRNA sponge; transcription

Year:  2021        PMID： 33643900      PMCID： PMC7905086          DOI： 10.3389/fonc.2020.586163

Source DB:  PubMed          Journal:  Front Oncol        ISSN： 2234-943X            Impact factor:   6.244


  40 in total

Review 1.  Circular RNA and its mechanisms in disease: From the bench to the clinic.

Authors:  Bing Han; Jie Chao; Honghong Yao
Journal:  Pharmacol Ther       Date:  2018-02-14       Impact factor: 12.310

Review 2.  Circular RNAs in Cancer: Biogenesis, Function, and Clinical Significance.

Authors:  Jiao Li; Dan Sun; Wenchen Pu; Jin Wang; Yong Peng
Journal:  Trends Cancer       Date:  2020-02-19

3.  A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis.

Authors:  Maolei Zhang; Nunu Huang; Xuesong Yang; Jingyan Luo; Sheng Yan; Feizhe Xiao; Wenping Chen; Xinya Gao; Kun Zhao; Huangkai Zhou; Ziqiang Li; Liu Ming; Bo Xie; Nu Zhang
Journal:  Oncogene       Date:  2018-01-18       Impact factor: 9.867

4.  Androgen receptor-regulated circFNTA activates KRAS signaling to promote bladder cancer invasion.

Authors:  Jinbo Chen; Yin Sun; Zhenyu Ou; Shuyuan Yeh; Chi-Ping Huang; Bosen You; Yu-Chieh Tsai; Tzong-Jen Sheu; Xiongbing Zu; Chawnshang Chang
Journal:  EMBO Rep       Date:  2020-02-13       Impact factor: 8.807

5.  Identification of the tumor-suppressive function of circular RNA ITCH in glioma cells through sponging miR-214 and promoting linear ITCH expression.

Authors:  Feng Li; Ke Ma; Meihua Sun; Shan Shi
Journal:  Am J Transl Res       Date:  2018-05-15       Impact factor: 4.060

6.  A novel FLI1 exonic circular RNA promotes metastasis in breast cancer by coordinately regulating TET1 and DNMT1.

Authors:  Naifei Chen; Gang Zhao; Xu Yan; Zheng Lv; Hongmei Yin; Shilin Zhang; Wei Song; Xueli Li; Lingyu Li; Zhonghua Du; Lin Jia; Lei Zhou; Wei Li; Andrew R Hoffman; Ji-Fan Hu; Jiuwei Cui
Journal:  Genome Biol       Date:  2018-12-11       Impact factor: 13.583

7.  Therapeutic targeting of circ-CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression.

Authors:  Huanhuan Li; Feng Yang; Anpei Hu; Xiaojing Wang; Erhu Fang; Yajun Chen; Dan Li; Huajie Song; Jianqun Wang; Yanhua Guo; Yang Liu; Hongjun Li; Kai Huang; Liduan Zheng; Qiangsong Tong
Journal:  EMBO Mol Med       Date:  2019-11-11       Impact factor: 12.137

Review 8.  Translation and functional roles of circular RNAs in human cancer.

Authors:  Ming Lei; Guantao Zheng; Qianqian Ning; Junnian Zheng; Dong Dong
Journal:  Mol Cancer       Date:  2020-02-15       Impact factor: 27.401

9.  Circular RNA hsa_circ_0001649 inhibits hepatocellular carcinoma progression via multiple miRNAs sponge.

Authors:  Yang Su; Chao Xu; Yuting Liu; Yilin Hu; Haiyan Wu
Journal:  Aging (Albany NY)       Date:  2019-05-28       Impact factor: 5.682

10.  Circular RNA SMO sponges miR-338-3p to promote the growth of glioma by enhancing the expression of SMO.

Authors:  Zhiyong Xiong; Chaoyang Zhou; Luyang Wang; Ronglan Zhu; Liangchen Zhong; Dengfeng Wan; Qiangping Wang
Journal:  Aging (Albany NY)       Date:  2019-12-30       Impact factor: 5.682
View more
  4 in total

1.  Circ-FOXM1 promotes the proliferation, migration and EMT process of osteosarcoma cells through FOXM1-mediated Wnt pathway activation.

Authors:  Hao Zhang; Qiongqiong Zhou; Weimin Shen
Journal:  J Orthop Surg Res       Date:  2022-07-07       Impact factor: 2.677

Review 2.  Circular RNAs modulate Hippo-YAP signaling: functional mechanisms in cancer.

Authors:  Javeria Qadir; Feiya Li; Burton B Yang
Journal:  Theranostics       Date:  2022-05-16       Impact factor: 11.600

3.  Genome-Wide Expression Profiling and Networking Reveals an Imperative Role of IMF-Associated Novel CircRNAs as ceRNA in Pigs.

Authors:  Salsabeel Yousuf; Ai Li; Hui Feng; Tianyi Lui; Wanlong Huang; Xiuxiu Zhang; Lingli Xie; Xiangyang Miao
Journal:  Cells       Date:  2022-08-24       Impact factor: 7.666

4.  Triptolide attenuates inhibition of ankylosing spondylitis-derived mesenchymal stem cells on the osteoclastogenesis through modulating exosomal transfer of circ-0110634.

Authors:  Wei Ji; Yueyang Lu; Zhuoyi Ma; Ke Gan; Yan Liu; Yue Cheng; Junliang Xu; Shijia Liu; Yunke Guo; Shanhang Han; Zengyan Zhao; Hanmei Xu; Weiyan Qi
Journal:  J Orthop Translat       Date:  2022-09-16       Impact factor: 4.889
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.