Literature DB >> 33643193

A Neurodisparity Index of Nationwide Access to Neurological Health Care in Northern Ireland.

Mark O McCarron1, Mike Clarke2, Paul Burns3, Michael McCormick4, Peter McCarron5, Raeburn B Forbes6, Luke V McCarron7, Fiona Mullan1, Ferghal McVerry1.   

Abstract

Nationwide disparities in managing neurological patients have rarely been reported. We compared neurological health care between the population who reside in a Health and Social Care Trust with a tertiary neuroscience center and those living in the four non-tertiary center Trusts in Northern Ireland. Using the tertiary center Trust population as reference, neurodisparity indices (NDIs) defined as the number of treated patients resident in each Trust per 100,000 residents compared to the same ratio in the tertiary center Trust for a fixed time period. NDIs were calculated for four neurological pathways-intravenous thrombolysis (iv-tPA) and mechanical thrombectomy (MT) for acute ischemic stroke (AIS), disease modifying treatment (DMT) in multiple sclerosis (MS) and admissions to a tertiary neurology ward. Neurological management was recorded in 3,026 patients. Patients resident in the tertiary center Trust were more likely to receive AIS treatments (iv-tPA and MT) and access to the neurology ward (p < 0.001) than patients residing in other Trusts. DMT use for patients with MS was higher in two non-tertiary center Trusts than in the tertiary center Trust. There was a geographical gradient for MT for AIS patients and ward admissions. Averaged NDIs for non-tertiary center Trusts were: 0.48 (95%CI 0.32-0.71) for patient admissions to the tertiary neurology ward, 0.50 (95%CI 0.38-0.66) for MT in AIS patients, 0.78 (95%CI 0.67-0.92) for iv-tPA in AIS patients, and 1.11 (95%CI 0.99-1.26) for DMT use in MS patients. There are important neurodisparities in Northern Ireland, particularly for MT and tertiary ward admissions. Neurologists and health service planners should be aware that geography and time-dependent management of neurological patients worsen neurodisparities.
Copyright © 2021 McCarron, Clarke, Burns, McCormick, McCarron, Forbes, McCarron, Mullan and McVerry.

Entities:  

Keywords:  disease modifying drug; disparities; mechanical thrombectomy; multiple sclerosis; stroke; thrombolysis (tPA)

Year:  2021        PMID: 33643193      PMCID: PMC7907594          DOI: 10.3389/fneur.2021.608070

Source DB:  PubMed          Journal:  Front Neurol        ISSN: 1664-2295            Impact factor:   4.003


  25 in total

1.  The value of a liaison neurology service in a district general hospital.

Authors:  P McColgan; A S Carr; M O McCarron
Journal:  Postgrad Med J       Date:  2010-12-23       Impact factor: 2.401

2.  The inverse care law.

Authors:  J T Hart
Journal:  Lancet       Date:  1971-02-27       Impact factor: 79.321

3.  Waiting times compared across the four UK nations.

Authors:  John Appleby
Journal:  BMJ       Date:  2019-11-07

4.  Prehospital selection of thrombectomy candidates beyond large vessel occlusion: M-DIRECT scale.

Authors:  Jorge Rodríguez-Pardo; Nicolas Riera-López; Blanca Fuentes; María Alonso de Leciñana; Sergio Secades-García; Julia Álvarez-Fraga; Pablo Busca-Ostolaza; Joaquín Carneado-Ruiz; Jaime Díaz-Guzmán; José Egido-Herrero; Antonio Gil-Núñez; Jaime Masjuan-Vallejo; Verónica Real-Martínez; José Vivancos-Mora; Exuperio Díez-Tejedor
Journal:  Neurology       Date:  2020-01-24       Impact factor: 9.910

5.  Randomized assessment of rapid endovascular treatment of ischemic stroke.

Authors:  Mayank Goyal; Andrew M Demchuk; Bijoy K Menon; Muneer Eesa; Jeremy L Rempel; John Thornton; Daniel Roy; Tudor G Jovin; Robert A Willinsky; Biggya L Sapkota; Dar Dowlatshahi; Donald F Frei; Noreen R Kamal; Walter J Montanera; Alexandre Y Poppe; Karla J Ryckborst; Frank L Silver; Ashfaq Shuaib; Donatella Tampieri; David Williams; Oh Young Bang; Blaise W Baxter; Paul A Burns; Hana Choe; Ji-Hoe Heo; Christine A Holmstedt; Brian Jankowitz; Michael Kelly; Guillermo Linares; Jennifer L Mandzia; Jai Shankar; Sung-Il Sohn; Richard H Swartz; Philip A Barber; Shelagh B Coutts; Eric E Smith; William F Morrish; Alain Weill; Suresh Subramaniam; Alim P Mitha; John H Wong; Mark W Lowerison; Tolulope T Sajobi; Michael D Hill
Journal:  N Engl J Med       Date:  2015-02-11       Impact factor: 91.245

Review 6.  Air-Mobile Stroke Unit for access to stroke treatment in rural regions.

Authors:  Silke Walter; Henry Zhao; Damien Easton; Cees Bil; Jonas Sauer; Yang Liu; Martin Lesmeister; Iris Q Grunwald; Geoffrey A Donnan; Stephen M Davis; Klaus Fassbender
Journal:  Int J Stroke       Date:  2018-08       Impact factor: 5.266

7.  Factors in the rising prevalence of multiple sclerosis in the north-east of Ireland.

Authors:  O M Gray; G V McDonnell; S A Hawkins
Journal:  Mult Scler       Date:  2008-06-23       Impact factor: 6.312

8.  Endovascular Thrombectomy for Acute Ischemic Stroke: A Meta-analysis.

Authors:  Jetan H Badhiwala; Farshad Nassiri; Waleed Alhazzani; Magdy H Selim; Forough Farrokhyar; Julian Spears; Abhaya V Kulkarni; Sheila Singh; Abdulrahman Alqahtani; Bram Rochwerg; Mohammad Alshahrani; Naresh K Murty; Adel Alhazzani; Blake Yarascavitch; Kesava Reddy; Osama O Zaidat; Saleh A Almenawer
Journal:  JAMA       Date:  2015-11-03       Impact factor: 56.272

9.  Centralising and optimising decentralised stroke care systems: a simulation study on short-term costs and effects.

Authors:  Maarten M H Lahr; Durk-Jouke van der Zee; Gert-Jan Luijckx; Patrick C A J Vroomen; Erik Buskens
Journal:  BMC Med Res Methodol       Date:  2017-01-10       Impact factor: 4.615

Review 10.  Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials.

Authors:  Jonathan Emberson; Kennedy R Lees; Patrick Lyden; Lisa Blackwell; Gregory Albers; Erich Bluhmki; Thomas Brott; Geoff Cohen; Stephen Davis; Geoffrey Donnan; James Grotta; George Howard; Markku Kaste; Masatoshi Koga; Ruediger von Kummer; Maarten Lansberg; Richard I Lindley; Gordon Murray; Jean Marc Olivot; Mark Parsons; Barbara Tilley; Danilo Toni; Kazunori Toyoda; Nils Wahlgren; Joanna Wardlaw; William Whiteley; Gregory J del Zoppo; Colin Baigent; Peter Sandercock; Werner Hacke
Journal:  Lancet       Date:  2014-08-05       Impact factor: 79.321

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