Literature DB >> 33642959

Full Analysis of Lung Cancer Mortality/Radon Relationship with Simple Nonlinear Concepts.

Ralph W Lai1.   

Abstract

We analyze the relationship between the lung cancer mortality and the indoor radon intensity from the viewpoint of nonlinear mathematics. We conclude that their relationship is governed by the proportionality law where the cumulative lung cancer mortality Y is negatively proportional to the cumulative radon intensity X; or specifically, the nonlinear change of nonlinear face value (qYu - qY) is negatively proportional to the nonlinear change of nonlinear face value (X - Xb). The author obtained a set of data from late Professor Cohen on the lung-cancer mortality rate versus indoor radon level collected from 1,597 counties and territory of the USA. We initially presented the data as various primitive elementary graphs; then extended them to the primary graphs, leading graphs, and the proportionality graphs. The article emphasizes the building of a straight-line proportionality relationship for the dose-response data in a log-linear and/or log-log graphs. It demonstrates a straightforward methodology for solving the key upper asymptotes (Yu) for the proportionality equation using the Microsoft Excel via determining the "coefficient of determination". (Note: q = log, Yu = upper asymptote of Y, Xb = bottom asymptote of X).
© The Author(s) 2021.

Entities:  

Keywords:  Alpha Beta (αβ) Math; Excel spreadsheet; coefficient of determination; nonlinear concepts; position (or integral) constant C; proportionality (or rate) constant K; regression equation; upper asymptote Yu

Year:  2021        PMID: 33642959      PMCID: PMC7894700          DOI: 10.1177/1559325820960994

Source DB:  PubMed          Journal:  Dose Response        ISSN: 1559-3258            Impact factor:   2.658


  2 in total

1.  Adaptive Responses Account for the beta-Curve-Hormesis is Linked to Acquired Tolerance.

Authors:  A R D Stebbing
Journal:  Nonlinearity Biol Toxicol Med       Date:  2003-10

2.  Test of the linear-no threshold theory of radiation carcinogenesis for inhaled radon decay products.

Authors:  B L Cohen
Journal:  Health Phys       Date:  1995-02       Impact factor: 1.316

  2 in total

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