Literature DB >> 33642915

Ruptured Small Intestinal Stromal Tumor Causing Concurrent Gastrointestinal and Intra-Abdominal Hemorrhage: A Case Report.

Yoichiro Tada1, Manabu Yamamoto1, Shohei Sawata1, Kazushi Hara1, Ken Sugesawa1, Chihiro Ueshima1, Akimitsu Tanio1, Kyoichi Kihara1, Tomoyuki Matsunaga1, Naruo Tokuyasu1, Shuichi Takano1, Teruhisa Sakamoto1, Soichiro Honjo1, Toshimichi Hasegawa1, Yoshiyuki Fujiwara1.   

Abstract

Gastrointestinal stromal tumors (GISTs) originate from mesenchymal cells throughout the gastrointestinal tract. A common symptom is gastrointestinal hemorrhage; intra-abdominal hemorrhage is relatively rare. There are few reports of GIST presenting with both types of hemorrhage concurrently. A 77-year-old man was admitted to our hospital because of melena and anemia (Hb: 4.7 g/dL). Computed tomography revealed a small bowel tumor and high-density fluid in both the small intestine and the pelvic floor. We diagnosed a small intestinal tumor with concurrent gastrointestinal and intra-abdominal hemorrhage, and performed emergency surgery. The tumor arose from the small intestine and was ruptured. We found hemorrhage in the pelvic cavity and performed partial small intestine resection. Pathological findings revealed that the tumor was positive for c-Kit protein and was diagnosed as GIST. The patient was discharged from the hospital on postoperative day 9 and received imatinib 1 month postoperatively. We experienced a very rare case of ruptured GIST originating from the small intestine associated with both gastrointestinal and intra-abdominal hemorrhage. We also reviewed the relevant literature. ©2021 Tottori University Medical Press.

Entities:  

Keywords:  gastrointestinal hemorrhage; gastrointestinal stromal tumor; intra-abdominal hemorrhage; rupture; small intestine

Year:  2021        PMID: 33642915      PMCID: PMC7902165          DOI: 10.33160/yam.2021.02.019

Source DB:  PubMed          Journal:  Yonago Acta Med        ISSN: 0513-5710            Impact factor:   1.641


  22 in total

1.  Simultaneous occurrence of obscure-overt gastrointestinal and intraperitoneal bleeding in gastrointestinal stromal tumor.

Authors:  Dong Yang Park; Won Moon
Journal:  Clin Gastroenterol Hepatol       Date:  2009-04-24       Impact factor: 11.382

2.  A ruptured ileal GI stromal tumor causing hemoperitoneum.

Authors:  El Ajmi Mahmoud; Fteriche Fadhel; Makni Amin; Rebai Wael; Daghfous Amin; Bedioui Haykel; Chebbi Faouzi; Ksantini Rachid; Jouini Mohamed; Kacem Montasser; Ben Safta Zoubeir
Journal:  Gastrointest Endosc       Date:  2009-10-31       Impact factor: 9.427

3.  Spontaneous rupture of extraluminal jejunal gastrointestinal stromal tumor causing acute abdomen and hemoperitoneum.

Authors:  Wafi Attaallah; Şafak Coşkun; Gülden Özden; Hande Mollamemişoğlu; Cumhur Yeğen
Journal:  Ulus Cerrahi Derg       Date:  2015-06-01

4.  Ruptured gastrointestinal stromal tumors: radiologic findings in six cases.

Authors:  M F Cegarra-Navarro; M A Corral de la Calle; E Girela-Baena; J M García-Santos; F Lloret-Estañ; E Parlorio de Andrés
Journal:  Abdom Imaging       Date:  2005-04-16

5.  Spontaneously ruptured gastrointestinal stromal tumor (GIST) of the jejunum mimicking acute appendicitis.

Authors:  Marko Ajduk; Danko Mikulić; Bozidar Sebecić; Slavko Gasparov; Leonardo Patrlj; Lidija Erdelez; Andrija Skopljanac; Mario Staresinić; Slobodan Desković; Tomislav Sosa; Sanda Sitić
Journal:  Coll Antropol       Date:  2004-12

6.  Efficacy and Clinical Outcomes of Transcatheter Arterial Embolization for Gastrointestinal Bleeding from Gastrointestinal Stromal Tumor.

Authors:  Hyun Jung Koo; Ji Hoon Shin; Sooyoung Shin; Hyun-Ki Yoon; Gi-Young Ko; Dong Il Gwon
Journal:  J Vasc Interv Radiol       Date:  2015-07-17       Impact factor: 3.464

7.  [A Case of Gastrointestinal Stromal Tumor of the Small Intestine Complicated by Hemorrhagic Shock Due to Gastrointestinal and Intraperitoneal Bleedings].

Authors:  Hiroki Kobayashi; Shoji Hirajima; Tsuyoshi Takagi; Kanehisa Fukumoto
Journal:  Gan To Kagaku Ryoho       Date:  2017-11

8.  Clinicopathological features and prognostic factors of rectal gastrointestinal stromal tumors.

Authors:  C C Xiao; S Zhang; M H Wang; L Y Huang; P Wu; Y Xu; X L Zhu; W Q Sheng; C Y Du; Y Q Shi; Z Q Guan; S J Cai; G X Cai
Journal:  J Gastrointest Surg       Date:  2013-01-04       Impact factor: 3.452

9.  A ruptured large extraluminal ileal gastrointestinal stromal tumor causing hemoperitoneum.

Authors:  Shoji Hirasaki; Kohei Fujita; Minoru Matsubara; Hiromitsu Kanzaki; Hiromichi Yamane; Masato Okuda; Seiyuu Suzuki; Atsuko Shirakawa; Hideyuki Saeki
Journal:  World J Gastroenterol       Date:  2008-05-14       Impact factor: 5.742

10.  SKP2 high expression, KIT exon 11 deletions, and gastrointestinal bleeding as predictors of poor prognosis in primary gastrointestinal stromal tumors.

Authors:  Ang Lv; Zhongwu Li; Xiuyun Tian; Xiaoya Guan; Min Zhao; Bin Dong; Chunyi Hao
Journal:  PLoS One       Date:  2013-05-17       Impact factor: 3.240

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  1 in total

1.  Successful En Bloc Resection of Complicated Giant Stomach Gastrointestinal Stromal Tumor in an Elderly Patient.

Authors:  Bryan Zhi Yong Yeoh; Vee Chuan Hoe; Shu Ning Kong; Wei Keat Ooi; Kar Yee Chiew; Firdaus Hayati
Journal:  Am J Case Rep       Date:  2022-01-07
  1 in total

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