Literature DB >> 33641498

Metastatic microcalcification in the lungs and stomach due to hyperparathyroidism: A case report.

Weiwei Xu1, Tao Hu2, Shuangzhi Lv3, Mengjie Dong2, Jun Yang2.   

Abstract

We present a case of a 34-year-old man who was admitted to our hospital with a six-month history of nausea and vomiting that had worsened over the past two weeks. Diagnosis of primary hyperparathyroidism (PHPT) due to a single parathyroid adenoma was confirmed by laboratory results and imaging but following pharmacological therapy the patient developed a dry cough. Single-photon emission tomography/computed tomography (SPECT/CT) with technetium-99m-diphosphonate (99mTc-MDP) was used to assist in the diagnosis and results showed diffuse metastatic microcalcification in the lungs and stomach. The patient underwent right parathyroidectomy and 99mTc-MDP SPECT/CT scan six months later showed a significantly reduced radioactive distribution in the lungs and none in the stomach. Diffuse metastatic microcalcification in the lungs and stomach due to PHTP is rare and can easily be misdiagnosed.

Entities:  

Keywords:  Metastatic microcalcification; hyperparathyroidism; lungs; parathyroid adenoma; stomach

Mesh:

Substances:

Year:  2021        PMID: 33641498      PMCID: PMC7917954          DOI: 10.1177/0300060521994420

Source DB:  PubMed          Journal:  J Int Med Res        ISSN: 0300-0605            Impact factor:   1.671


  20 in total

1.  Severe Metastatic Pulmonary Calcification.

Authors:  Masaya Taniwaki; Kazuma Kawamoto; Masahiro Yamasaki; Kunihiko Funaishi; Yu Matsumoto; Naoko Matsumoto; Nobuyuki Ohashi; Noboru Hattori
Journal:  Am J Med       Date:  2019-05-15       Impact factor: 4.965

2.  Primary hyperparathyroidism presenting with cough and dyspnea.

Authors:  Xianhua Gui; Liyun Miao; Hourong Cai; Fanqing Meng
Journal:  Chin Med J (Engl)       Date:  2014       Impact factor: 2.628

Review 3.  Primary Hyperparathyroidism.

Authors:  John P Bilezikian
Journal:  J Clin Endocrinol Metab       Date:  2018-11-01       Impact factor: 5.958

4.  A hyperparathyroid case with pulmonary edema: can hypercalcemia trigger pulmonary edema?

Authors:  Meral Mert; Fatma Betül Uzuncan; Munevver Mertsoylu Aydin; Gonenc Kocabay; Adile Ortaköylü
Journal:  Am J Emerg Med       Date:  2011-02-26       Impact factor: 2.469

Review 5.  Hyperparathyroidism.

Authors:  John P Bilezikian; Leonardo Bandeira; Aliya Khan; Natalie E Cusano
Journal:  Lancet       Date:  2017-09-17       Impact factor: 79.321

Review 6.  Diffuse pulmonary uptake of 99mTc bone-imaging agents: case report and survey.

Authors:  J L Coolens; P Devos; M De Roo
Journal:  Eur J Nucl Med       Date:  1985

Review 7.  Metastatic pulmonary calcification: state-of-the-art review focused on imaging findings.

Authors:  Luciana Camara Belém; Gláucia Zanetti; Arthur Soares Souza; Bruno Hochhegger; Marcos Duarte Guimarães; Luiz Felipe Nobre; Rosana Souza Rodrigues; Edson Marchiori
Journal:  Respir Med       Date:  2014-02-06       Impact factor: 3.415

Review 8.  Calcium deposition with or without bone formation in the lung.

Authors:  Edward D Chan; Donald V Morales; Carolyn H Welsh; Michael T McDermott; Marvin I Schwarz
Journal:  Am J Respir Crit Care Med       Date:  2002-06-15       Impact factor: 21.405

Review 9.  Rapid development of metastatic pulmonary calcifications in primary hyperparathyroidism: a case report and literature review.

Authors:  Hui-Ming Sun; Fei Chen; Hong-Lin Yin; Xiao-Yong Xu; Hong-Bing Liu; Bei-Lei Zhao
Journal:  Diagn Pathol       Date:  2017-05-08       Impact factor: 2.644

10.  Metastatic pulmonary calcification as a rare complication of end-stage renal disease with coexistence of pulmonary metastases from renal cell carcinoma: case report and literature review.

Authors:  Marta Michali-Stolarska; Anna Zacharzewska-Gondek; Joanna Bladowska; Maciej Guziński; Marek J Sąsiadek
Journal:  Pol J Radiol       Date:  2018-04-01
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