Literature DB >> 3364045

[Comparative morphine determination in parts of the brain using combined gas chromatography/mass spectrometry. A possibility for assessing survival time].

W Vycudilik1.   

Abstract

Comparison of the morphine concentrations in the medulla oblongata and the cerebellum provides information on the interval between morphine administration and death. If this period is short, the ratio of CMed:CCereb is below 1. The ratio is above 1 if a number of hours have passed at least. The balance of the morphine concentrations is achieved within a few hours. Results have been achieved by gas chromatography/mass spectrometry analysis in about 100 autopsy cases.

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Year:  1988        PMID: 3364045     DOI: 10.1007/bf00204437

Source DB:  PubMed          Journal:  Z Rechtsmed        ISSN: 0044-3433


  7 in total

1.  [The determination of barbiturates in biological matter].

Authors:  W Vycudilik
Journal:  Beitr Gerichtl Med       Date:  1977

2.  Distribution of stereospecific binding of the potent narcotic analgesic etorphine in the human brain: predominance in the limbic system.

Authors:  J M Hiller; J Pearson; E J Simon
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1973-11

3.  Determination of morphine in serum and cerebrospinal fluid by gas chromatography and selected ion monitoring after reversed-phase column extraction.

Authors:  R H Drost; R D van Ooijen; T Ionescu; R A Maes
Journal:  J Chromatogr       Date:  1984-09-14

4.  Simultaneous identification and quantitation of codeine and morphine in urine by capillary gas chromatography and mass spectroscopy.

Authors:  B D Paul; L D Mell; J M Mitchell; J Irving; A J Novak
Journal:  J Anal Toxicol       Date:  1985 Sep-Oct       Impact factor: 3.367

5.  Morphine persistence in rat brain and serum after single doses.

Authors:  K B Mullis; D C Perry; A M Finn; B Stafford; W Sadée
Journal:  J Pharmacol Exp Ther       Date:  1979-02       Impact factor: 4.030

6.  Morphine concentrations in brain tissue from heroin-associated deaths.

Authors:  E M Pare; J R Monforte; R J Thibert
Journal:  J Anal Toxicol       Date:  1984 Sep-Oct       Impact factor: 3.367

7.  Multiple opiate receptor in human brain: an autoradiographic investigation.

Authors:  R Maurer; R Cortés; A Probst; J M Palacios
Journal:  Life Sci       Date:  1983       Impact factor: 5.037

  7 in total
  4 in total

1.  Morphine in postmortem blood: its importance for the diagnosis of deaths associated with opiate addiction.

Authors:  C Staub; R Jeanmonod; O Fryc
Journal:  Int J Legal Med       Date:  1990-12       Impact factor: 2.686

2.  Postmortem distribution pattern of morphine and morphine glucuronides in heroin overdose.

Authors:  G Skopp; R Lutz; B Ganssmann; R Mattern; R Aderjan
Journal:  Int J Legal Med       Date:  1996       Impact factor: 2.686

3.  Micromorphological changes in cardiac tissue of drug-related deaths with emphasis on chronic illicit opioid abuse.

Authors:  Monika H Seltenhammer; Katharina Marchart; Pia Paula; Nicole Kordina; Nikolaus Klupp; Barbara Schneider; Christine Fitzl; Daniele U Risser
Journal:  Addiction       Date:  2013-04-12       Impact factor: 6.526

4.  Aspiration in lethal drug abuse-a consequence of opioid intoxication.

Authors:  Johannes Nicolakis; Günter Gmeiner; Christian Reiter; Monika Heidemarie Seltenhammer
Journal:  Int J Legal Med       Date:  2020-09-14       Impact factor: 2.686

  4 in total

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