Literature DB >> 33640436

Induced Pluripotent Stem Cell-derived Hepatocytes From Patients With Nonalcoholic Fatty Liver Disease Display a Disease-specific Gene Expression Profile.

Caroline C Duwaerts1, Dounia Le Guillou1, Chris L Her1, Nathaniel J Phillips2, Holger Willenbring3, Aras N Mattis4, Jacquelyn J Maher5.   

Abstract

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Year:  2021        PMID： 33640436      PMCID： PMC8169560          DOI： 10.1053/j.gastro.2021.02.050

Source DB:  PubMed          Journal:  Gastroenterology        ISSN： 0016-5085            Impact factor:   33.883


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  8 in total

1.  Human Pluripotent Stem Cell-Derived Organoids as Models of Liver Disease.

Authors:  Muhammad Nadzim Bin Ramli; Yee Siang Lim; Chwee Tat Koe; Deniz Demircioglu; Weiquan Tng; Kevin Andrew Uy Gonzales; Cheng Peow Tan; Iwona Szczerbinska; Hongqing Liang; Einsi Lynn Soe; Zhiping Lu; Chaiyaboot Ariyachet; Ka Man Yu; Shu Hui Koh; Lai Ping Yaw; Nur Halisah Binte Jumat; John Soon Yew Lim; Graham Wright; Asim Shabbir; Yock Young Dan; Huck-Hui Ng; Yun-Shen Chan
Journal:  Gastroenterology       Date:  2020-06-15       Impact factor: 22.682

2.  Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids.

Authors:  Rie Ouchi; Shodai Togo; Masaki Kimura; Tadahiro Shinozawa; Masaru Koido; Hiroyuki Koike; Wendy Thompson; Rebekah A Karns; Christopher N Mayhew; Patrick S McGrath; Heather A McCauley; Ran-Ran Zhang; Kyle Lewis; Shoyo Hakozaki; Autumn Ferguson; Norikazu Saiki; Yosuke Yoneyama; Ichiro Takeuchi; Yo Mabuchi; Chihiro Akazawa; Hiroshi Y Yoshikawa; James M Wells; Takanori Takebe
Journal:  Cell Metab       Date:  2019-05-30       Impact factor: 27.287

3.  Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism.

Authors:  Alexandra Collin de l'Hortet; Kazuki Takeishi; Jorge Guzman-Lepe; Kazutoyo Morita; Abhinav Achreja; Branimir Popovic; Yang Wang; Kan Handa; Anjali Mittal; Noah Meurs; Ziwen Zhu; Frank Weinberg; Michael Salomon; Ira J Fox; Chu-Xia Deng; Deepak Nagrath; Alejandro Soto-Gutierrez
Journal:  Cell Metab       Date:  2019-08-06       Impact factor: 27.287

4.  Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling.

Authors:  Debanjan Dhar; Laura Antonucci; Hayato Nakagawa; Ju Youn Kim; Elisabeth Glitzner; Stefano Caruso; Shabnam Shalapour; Ling Yang; Mark A Valasek; Sooyeon Lee; Kerstin Minnich; Ekihiro Seki; Jan Tuckermann; Maria Sibilia; Jessica Zucman-Rossi; Michael Karin
Journal:  Cancer Cell       Date:  2018-06-11       Impact factor: 31.743

5.  Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients.

Authors:  Andreas Teufel; Timo Itzel; Wiebke Erhart; Mario Brosch; Xiao Yu Wang; Yong Ook Kim; Witigo von Schönfels; Alexander Herrmann; Stefan Brückner; Felix Stickel; Jean-François Dufour; Triantafyllos Chavakis; Claus Hellerbrand; Rainer Spang; Thorsten Maass; Thomas Becker; Stefan Schreiber; Clemens Schafmayer; Detlef Schuppan; Jochen Hampe
Journal:  Gastroenterology       Date:  2016-06-16       Impact factor: 22.682

6.  Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis.

Authors:  Changyu Zhu; KyeongJin Kim; Xiaobo Wang; Alberto Bartolome; Marcela Salomao; Paola Dongiovanni; Marica Meroni; Mark J Graham; Katherine P Yates; Anna Mae Diehl; Robert F Schwabe; Ira Tabas; Luca Valenti; Joel E Lavine; Utpal B Pajvani
Journal:  Sci Transl Med       Date:  2018-11-21       Impact factor: 19.319

7.  Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis.

Authors:  Madlen Matz-Soja; Christiane Rennert; Kristin Schönefeld; Susanne Aleithe; Jan Boettger; Wolfgang Schmidt-Heck; Thomas S Weiss; Amalya Hovhannisyan; Sebastian Zellmer; Nora Klöting; Angela Schulz; Jürgen Kratzsch; Reinhardt Guthke; Rolf Gebhardt
Journal:  Elife       Date:  2016-05-17       Impact factor: 8.140

8.  A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.

Authors:  Connor A Emdin; Mary E Haas; Amit V Khera; Krishna Aragam; Mark Chaffin; Derek Klarin; George Hindy; Lan Jiang; Wei-Qi Wei; Qiping Feng; Juha Karjalainen; Aki Havulinna; Tuomo Kiiskinen; Alexander Bick; Diego Ardissino; James G Wilson; Heribert Schunkert; Ruth McPherson; Hugh Watkins; Roberto Elosua; Matthew J Bown; Nilesh J Samani; Usman Baber; Jeanette Erdmann; Namrata Gupta; John Danesh; Danish Saleheen; Kyong-Mi Chang; Marijana Vujkovic; Ben Voight; Scott Damrauer; Julie Lynch; David Kaplan; Marina Serper; Philip Tsao; Josep Mercader; Craig Hanis; Mark Daly; Joshua Denny; Stacey Gabriel; Sekar Kathiresan
Journal:  PLoS Genet       Date:  2020-04-13       Impact factor: 5.917
  8 in total
  3 in total

1.  Induced Pluripotent Stem Cells From Subjects With Primary Sclerosing Cholangitis Develop a Senescence Phenotype Following Biliary Differentiation.

Authors:  Nidhi Jalan-Sakrikar; Thiago M De Assuncao; Amaia Navarro-Corcuera; Feda H Hamdan; Lorena Loarca; Lindsey A Kirkeby; Zachary T Resch; Steven P O'Hara; Brian D Juran; Konstantinos N Lazaridis; Charles B Rosen; Julie K Heimbach; Timucin Taner; Vijay H Shah; Nicholas F LaRusso; Robert C Huebert
Journal:  Hepatol Commun       Date:  2021-08-25

Review 2.  Advancements in MAFLD Modeling with Human Cell and Organoid Models.

Authors:  Shi-Xiang Wang; Ji-Song Yan; Yun-Shen Chan
Journal:  Int J Mol Sci       Date:  2022-10-06       Impact factor: 6.208

Review 3.  From NAFLD to MAFLD: Aligning Translational In Vitro Research to Clinical Insights.

Authors:  Alexandra Gatzios; Matthias Rombaut; Karolien Buyl; Joery De Kock; Robim M Rodrigues; Vera Rogiers; Tamara Vanhaecke; Joost Boeckmans
Journal:  Biomedicines       Date:  2022-01-12
  3 in total

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