| Literature DB >> 33637840 |
Manal Mahmoud Hamed1, Fayaz Ahmad Mir2, Emad Bashier Ibrahim Elmagboul2, Abdullatif Al-Khal2, Muna A Rahman S Al Maslamani2, Anand Sarwottam Deshmukh2, Hamad Eid Al-Romaihi3, Mohd Ahmed M Sharif Janahi2, Fatma Ben Abid2, Adila Shaukat Ali Kashaf2, Gulab Sher2, Vinod Kumar Gupta2, Godwin J Wilson2, Junais Kadalayi2, Sanjay H Doiphode2.
Abstract
The aim of the current study is to review the molecular characteristics of Neisseria meningitidis (N. meningitidis) in Hamad Medical Corporation, which is the provider of secondary and tertiary care in the state of Qatar. A total of 39 isolates of N. meningitidis from the period of 2013 to 2018 were revived and identified by Vitek, and susceptibility on the basis of the E test was retrieved from the patient's files. The revived isolates were subjected to multilocus sequence typing. The most common serogroup (19) of N. meningitidis was W135, of which 12 were isolated from blood and CSF. ST-11 was the most predominant ST clonal complex causing N. meningitidis cases (61.53%). Clonal complex ST-41/44 was the second most observed complex (3, 2 of which were related to serogroup B). The most frequent sequence type was 9596 (8 isolates). Determining the molecular pattern of N. meningitidis in Qatar is helpful for understanding the strains circulating in Qatar, and the study of the resistance trend of such strains may be very helpful for empirical treatment of future patients.Entities:
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Year: 2021 PMID： 33637840 PMCID： PMC7910605 DOI： 10.1038/s41598-021-84262-1
Source DB: PubMed Journal: Sci Rep ISSN： 2045-2322 Impact factor: 4.379