Literature DB >> 33637124

Exercise intervention protocol in children and young adults with cerebral palsy: the effects of strength, flexibility and gait training on physical performance, neuromuscular mechanisms and cardiometabolic risk factors (EXECP).

Pedro Valadão1, Harri Piitulainen2,3, Eero A Haapala2,4, Tiina Parviainen5, Janne Avela2, Taija Finni2.   

Abstract

BACKGROUND: Individuals with cerebral palsy (CP) have problems in everyday tasks such as walking and climbing stairs due to a combination of neuromuscular impairments such as spasticity, muscle weakness, reduced joint flexibility and poor coordination. Development of evidence-based interventions are in pivotal role in the development of better targeted rehabilitation of CP, and thus in maintaining their motor function and wellbeing. Our aim is to investigate the efficacy of an individually tailored, multifaceted exercise intervention (EXECP) in children and young adults with CP. EXECP is composed of strength, flexibility and gait training. Furthermore, this study aims to verify the short-term retention of the adaptations three months after the end of the EXECP intervention.
METHODS: Twenty-four children and young adults with spastic CP will be recruited to participate in a 9-month research project with a 3-month training intervention, consisting of two to three 90-min sessions per week. In each session, strength training for the lower limbs and trunk muscles, flexibility training for the lower limbs and inclined treadmill gait training will be performed. We will evaluate muscle strength, joint flexibility, neuromuscular and cardiometabolic parameters. A nonconcurrent multiple baseline design with two pre-tests and two post-tests all interspaced by three months is used. In addition to the CP participants, 24 typically developing age and sex-matched participants will perform the two pre-tests (i.e. no intervention) to provide normative data. DISCUSSION: This study has a comprehensive approach examining longitudinal effects of wide variety of variables ranging from physical activity and gross motor function to sensorimotor functions of the brain and neuromuscular and cardiometabolic parameters, providing novel information about the adaptation mechanisms in cerebral palsy. To the best of our knowledge, this is the first intervention study providing supervised combined strength, flexibility and gait training for young individuals with CP. TRIAL REGISTRATION NUMBER: ISRCTN69044459, prospectively registered (21/04/2017).

Entities:  

Keywords:  Cardiometabolic; Cerebral palsy; Flexibility; Gait; Neuromuscular; Strength; Training

Year:  2021        PMID: 33637124     DOI: 10.1186/s13102-021-00242-y

Source DB:  PubMed          Journal:  BMC Sports Sci Med Rehabil        ISSN: 2052-1847


  96 in total

1.  Prevalence and functioning of children with cerebral palsy in four areas of the United States in 2006: a report from the Autism and Developmental Disabilities Monitoring Network.

Authors:  Russell S Kirby; Martha S Wingate; Kim Van Naarden Braun; Nancy S Doernberg; Carrie L Arneson; Ruth E Benedict; Beverly Mulvihill; Maureen S Durkin; Robert T Fitzgerald; Matthew J Maenner; Jean A Patz; Marshalyn Yeargin-Allsopp
Journal:  Res Dev Disabil       Date:  2011-01-26

2.  A report: the definition and classification of cerebral palsy April 2006.

Authors:  Peter Rosenbaum; Nigel Paneth; Alan Leviton; Murray Goldstein; Martin Bax; Diane Damiano; Bernard Dan; Bo Jacobsson
Journal:  Dev Med Child Neurol Suppl       Date:  2007-02

3.  An update on the treatment of gait problems in cerebral palsy.

Authors:  J R Gage; T F Novacheck
Journal:  J Pediatr Orthop B       Date:  2001-10       Impact factor: 1.041

Review 4.  Contractures in orthopaedic and neurological conditions: a review of causes and treatment.

Authors:  S E Farmer; M James
Journal:  Disabil Rehabil       Date:  2001-09-10       Impact factor: 3.033

5.  Trends in the prevalence of cerebral palsy in a population-based study.

Authors:  Sarah Winter; Andrew Autry; Coleen Boyle; Marshalyn Yeargin-Allsopp
Journal:  Pediatrics       Date:  2002-12       Impact factor: 7.124

6.  Does loss of spasticity matter? A 10-year follow-up after selective dorsal rhizotomy in cerebral palsy.

Authors:  Kristina Tedroff; Kristina Löwing; Dan N O Jacobson; Eva Åström
Journal:  Dev Med Child Neurol       Date:  2011-05-18       Impact factor: 5.449

7.  Passive, intrinsic and reflex-mediated stiffness in the ankle extensors of hemiparetic patients.

Authors:  T Sinkjaer; I Magnussen
Journal:  Brain       Date:  1994-04       Impact factor: 13.501

Review 8.  Structural and functional changes in spastic skeletal muscle.

Authors:  Richard L Lieber; Suzanne Steinman; Ilona A Barash; Hank Chambers
Journal:  Muscle Nerve       Date:  2004-05       Impact factor: 3.217

9.  Impaired gait function in adults with cerebral palsy is associated with reduced rapid force generation and increased passive stiffness.

Authors:  Svend Sparre Geertsen; Henrik Kirk; Jakob Lorentzen; Martin Jorsal; Claus Bo Johansson; Jens Bo Nielsen
Journal:  Clin Neurophysiol       Date:  2015-02-21       Impact factor: 3.708

10.  Long-term effects of botulinum toxin A in children with cerebral palsy.

Authors:  Kristina Tedroff; Fredrik Granath; Hans Forssberg; Yvonne Haglund-Akerlind
Journal:  Dev Med Child Neurol       Date:  2009-02       Impact factor: 5.449

View more
  1 in total

Review 1.  Physical activity intention and attendance behaviour in Finnish youth with cerebral palsy - results from a physical activity intervention: an application of the theory of planned behaviour.

Authors:  Alfredo Ruiz; Kwok Ng; Pauli Rintala; Kaisa Kaseva; Taija Finni
Journal:  J Exerc Rehabil       Date:  2021-12-27
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.