Literature DB >> 33634533

Dietary protein content and digestibility influences discrimination of amino acid nitrogen isotope values in a terrestrial omnivorous mammal.

John P Whiteman1,2, Mauriel Rodriguez Curras2,3, Kelli L Feeser2,4, Seth D Newsome2.   

Abstract

RATIONALE: Ecologists increasingly determine the δ15 N values of amino acids (AA) in animal tissue; "source" AA typically exhibit minor variation between diet and consumer, while "trophic" AA have increased δ15 N values in consumers. Thus, trophic-source δ15 N offsets (i.e., Δ15 NT-S ) reflect trophic position in a food web. However, even minor variations in δ15 Nsource AA values may influence the magnitude of offset that represents a trophic step, known as the trophic discrimination factor (i.e., TDFT-S ). Diet digestibility and protein content can influence the δ15 N values of bulk animal tissue, but the effects of these factors on AA Δ15 NT-S and TDFT-S in mammals are unknown.
METHODS: We fed captive mice (Mus musculus) either (A) a low-fat, high-fiber diet with low, intermediate, or high protein; or (B) a high-fat, low-fiber diet with low or intermediate protein. Mouse muscle and dietary protein were analyzed for bulk tissue δ15 N using elemental analyzer-isotope ratio mass spectrometry (EA-IRMS), and were also hydrolyzed into free AA that were analyzed for δ15 N using gas chromatography-combustion-IRMS.
RESULTS: As dietary protein increased, Δ15 NConsumer-Diet slightly declined for bulk muscle tissue in both experiments; increased for AA in the low-fat, high-fiber diet (A); and remained the same or decreased for AA in the high-fat, low-fiber diet (B). The effects of dietary protein on Δ15 NT-S and on TDFT-S varied by AA but were consistent between variables.
CONCLUSIONS: Diets were less digestible and included more protein in Experiment A than in Experiment B. As a result, the mice in Experiment A probably oxidized more AA, resulting in greater Δ15 NConsumer-Diet values. However, the similar responses of Δ15 NT-S and of TDFT-S to diet variation suggest that if diet samples are available, Δ15 NT-S accurately tracks trophic position. If diet samples are not available, the patterns presented here provide a basis to interpret Δ15 NT-S values. The trophic-source offset of Pro-Lys did not vary across diets, and therefore may be more reliable for omnivores than other offsets (e.g., Glu-Phe).
© 2021 John Wiley & Sons Ltd.

Entities:  

Year:  2021        PMID: 33634533     DOI: 10.1002/rcm.9073

Source DB:  PubMed          Journal:  Rapid Commun Mass Spectrom        ISSN: 0951-4198            Impact factor:   2.419


  3 in total

1.  Bulk and amino acid nitrogen isotopes suggest shifting nitrogen balance of pregnant sharks across gestation.

Authors:  Oliver N Shipley; Jill A Olin; John P Whiteman; Dana M Bethea; Seth D Newsome
Journal:  Oecologia       Date:  2022-06-20       Impact factor: 3.225

2.  Reconstructing Hominin Diets with Stable Isotope Analysis of Amino Acids: New Perspectives and Future Directions.

Authors:  Thomas Larsen; Ricardo Fernandes; Yiming V Wang; Patrick Roberts
Journal:  Bioscience       Date:  2022-05-23       Impact factor: 11.566

3.  Extreme bill dimorphism leads to different but overlapping isotopic niches and similar trophic positions in sexes of the charismatic extinct huia.

Authors:  Barbara M Tomotani; Rodrigo B Salvador; Amandine J M Sabadel; Colin M Miskelly; Julie C S Brown; Josette Delgado; Patrick Boussès; Yves Cherel; Susan M Waugh; Sarah J Bury
Journal:  Oecologia       Date:  2021-11-29       Impact factor: 3.225

  3 in total

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