Walaa Shahin 1 , Walaa Rabie 1 , Osama Alyossof 1 , Mohammed Alasiri 1 , Mohamed Alfaki 1 , Elamin Mahmoud 1 , Muwaffak Hijazi 1 , Huda El Faraidi 1 , Hassan Alahmari 1 Show Affiliations »
Abstract
OBJECTIVES: To identify clinical and laboratory characteristics of the Saudi children with confirmed COVID-19. METHODS: Eighty-eight children (0-14 years) with COVID-19 who were admitted to Prince Sultan Military Medical City (PSMMC), Riyadh, Saudi Arabia from April to June 2020 were recruited. RESULTS: Mean age was 5.74 ± 4.7 years with 41 (49.4%) males and 42 (50.6%) females. The length of hospital stay (LOS) ranged from 1 to 17 days. The main source of infection was infected family members. Mean values of C-reactive protein (CRP), serum ferritin, and lactate dehydrogenase (LDH) were noticeably above normal. Degree of severity and length of stay was significantly correlated with lymphopenia (r= -0.36; p=0.001), whereas it was positively correlated with absolute neutrophil count and with high inflammatory markers, such as CRP, LDH, and others. CONCLUSIONS: Identifying the clinical and laboratory characteristics of the Saudi children with confirmed COVID-19 will improve understanding of this disease's presentation and will help put rapid and proper management strategies into place to face this pandemic. A high index of suspicion is needed for cases presenting with multi-system inflammatory disease, which represented 5.7% of the included study population. Copyright: © Saudi Medical Journal.
OBJECTIVES: To identify clinical and laboratory characteristics of the Saudi children with confirmed COVID-19 . METHODS: Eighty-eight children (0-14 years) with COVID-19 who were admitted to Prince Sultan Military Medical City (PSMMC), Riyadh, Saudi Arabia from April to June 2020 were recruited. RESULTS: Mean age was 5.74 ± 4.7 years with 41 (49.4%) males and 42 (50.6%) females. The length of hospital stay (LOS) ranged from 1 to 17 days. The main source of infection was infected family members. Mean values of C-reactive protein (CRP ), serum ferritin, and lactate dehydrogenase (LDH) were noticeably above normal. Degree of severity and length of stay was significantly correlated with lymphopenia (r= -0.36; p=0.001), whereas it was positively correlated with absolute neutrophil count and with high inflammatory markers, such as CRP , LDH, and others. CONCLUSIONS: Identifying the clinical and laboratory characteristics of the Saudi children with confirmed COVID-19 will improve understanding of this disease's presentation and will help put rapid and proper management strategies into place to face this pandemic. A high index of suspicion is needed for cases presenting with multi-system inflammatory disease , which represented 5.7% of the included study population. Copyright: © Saudi Medical Journal.
Entities: Chemical
Disease
Gene
Species
Keywords:
COVID-19; MIS-c; Multisystem inflammatory disease; Saudi Arabia; children; pediatric
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Year: 2021
PMID： 33632909 DOI： 10.15537/smj.2021.42.3.20200625
Source DB: PubMed Journal: Saudi Med J ISSN： 0379-5284 Impact factor: 1.484