Literature DB >> 33632659

[Pharmacological treatment of non-severe hypertension during pregnancy, postpartum and breastfeeding].

A M Ghelfi1, M V Ferretti2, G J Staffieri3.   

Abstract

Hypertension (HTN) in pregnancy is defined as systolic blood pressure ≥ 140 and/or diastolic blood pressure ≥ 90 mmHg. Based on the values, it is classified as non-severe (< 160/110 mmHg) and severe (≥ 160/110 mmHg). Before starting treatment in non-severe HTN, white- coat HTN should be ruled out. If outpatient management is possible, pharmacological initiation is suggested with sustained high values, avoiding < 120/80 mmHg. Safe drugs during pregnancy are methyldopa, labetalol, and nifedipine-retard. The use of nifedipine-XL or amlodipine can be considered with a lower level of evidence of safety. Diuretics, atenolol, and other beta-blockers for antihypertensive purposes is not recommended in this period. Renin-angiotensin-aldosterone system inhibitors are strictly contraindicated. In postpartum and breastfeeding, the same therapeutic regimen used during pregnancy can be maintained, trying early withdrawal of methyldopa. During puerperium, amlodipine and enalapril are safe, with minimal excretion in breast milk.
Copyright © 2021 SEH-LELHA. Publicado por Elsevier España, S.L.U. All rights reserved.

Entities:  

Keywords:  Antihipertensivos; Antihypertensive agents; Breast feeding; Embarazo; Hipertensión arterial; Hypertension; Lactancia; Posparto; Postpartum; Pregnancy; Tratamiento; Treatment

Mesh:

Substances:

Year:  2021        PMID: 33632659     DOI: 10.1016/j.hipert.2021.01.002

Source DB:  PubMed          Journal:  Hipertens Riesgo Vasc        ISSN: 1889-1837


  1 in total

1.  Effects of Misoprostol on Induction of Labour in Patients with Hypertensive Disorders of Pregnancy: A Meta-Analysis.

Authors:  Leilei Wang; Sishi Liu; Guiyu Song; Man Gao; Tong Liu
Journal:  J Healthc Eng       Date:  2022-04-08       Impact factor: 2.682

  1 in total

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