Literature DB >> 3363227

Inhibition of glyoxalase I by various clinically used anticancer drugs.

J L Kraus1, P Pernice, C Ponce.   

Abstract

The antiglyoxalase activity of eight well-known anticancer drugs has been evaluated, their I50 values were determinated and compared to those of standard inhibitors S-octylglutathione and squaric acid. Among them methotrexate was found to be as potent as S-octylglutathione.

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Year:  1988        PMID: 3363227

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN: 0034-5164


  1 in total

1.  Angiogenesis impairment in diabetes: role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2.

Authors:  Hongtao Liu; Shujie Yu; Hua Zhang; Jian Xu
Journal:  PLoS One       Date:  2012-10-03       Impact factor: 3.240

  1 in total

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