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Literature DB >> 33630809

Comparison of 68Ga-FAPI and 18F-FDG PET/CT in the Imaging of Pancreatic Cancer With Liver Metastases.

Abstract

ABSTRACT: A 65-year-old man with suspected pancreatic cancer underwent 18F-FDG PET/CT for initial staging. Mild FDG uptake was observed in the pancreatic mass and bone destruction in the 10th rib on the right. No significant FDG uptake was seen with the multiple hypodense or isodense nodules in the liver. However, 68Ga-FAPI PET/CT revealed intense FAPI uptake in the pancreas and the 10th rib and multiple lesions in the liver. Finally, a biopsy confirmed carcinoma in the head of the pancreas with liver metastasis. This case highlighted that 68Ga-FAPI may outperform 18F-FDG PET/CT in identifying micrometastases of bones and hidden liver metastases.

Entities: Chemical Disease

Year: 2021 PMID： 33630809 DOI： 10.1097/RLU.0000000000003561

Source DB: PubMed Journal: Clin Nucl Med ISSN： 0363-9762 Impact factor: 7.794

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Cited

4 in total

1. Distinguishing Benign and Malignant Findings on [⁶⁸ Ga]-FAPI PET/CT Based on Quantitative SUV Measurements.

Authors: M Dabir; E Novruzov; K Mattes-György; M Beu; K Dendl; C Antke; S A Koerber; M Röhrich; C Kratochwil; J Debus; U Haberkorn; F L Giesel
Journal: Mol Imaging Biol Date: 2022-08-23 Impact factor: 3.484

2. The Application of [⁶⁸Ga]-Labeled FAPI-04 PET/CT for Targeting and Early Detection of Pancreatic Carcinoma in Patient-Derived Orthotopic Xenograft Models.

Authors: He Zhang; Jiaze An; Pengpeng Wu; Caiqin Zhang; Yong Zhao; Dengxu Tan; Changhong Shi; Xu Ge
Journal: Contrast Media Mol Imaging Date: 2022-08-05 Impact factor: 3.009

3. From Automated Synthesis to In Vivo Application in Multiple Types of Cancer-Clinical Results with [⁶⁸Ga]Ga-DATA^5m.SA.FAPi.

Authors: Lukas Greifenstein; Carsten S Kramer; Euy Sung Moon; Frank Rösch; Andre Klega; Christian Landvogt; Corinna Müller; Richard P Baum
Journal: Pharmaceuticals (Basel) Date: 2022-08-14

Review 4. FAPI PET/CT in the Diagnosis of Abdominal and Pelvic Tumors.

Authors: Tianshuo Yang; Long Ma; Haodong Hou; Feng Gao; Weijing Tao
Journal: Front Oncol Date: 2022-01-04 Impact factor: 6.244

4 in total

Comparison of 68Ga-FAPI and 18F-FDG PET/CT in the Imaging of Pancreatic Cancer With Liver Metastases.

1. Distinguishing Benign and Malignant Findings on [68 Ga]-FAPI PET/CT Based on Quantitative SUV Measurements.

2. The Application of [68Ga]-Labeled FAPI-04 PET/CT for Targeting and Early Detection of Pancreatic Carcinoma in Patient-Derived Orthotopic Xenograft Models.

3. From Automated Synthesis to In Vivo Application in Multiple Types of Cancer-Clinical Results with [68Ga]Ga-DATA5m.SA.FAPi.

Review 4. FAPI PET/CT in the Diagnosis of Abdominal and Pelvic Tumors.

1. Distinguishing Benign and Malignant Findings on [⁶⁸ Ga]-FAPI PET/CT Based on Quantitative SUV Measurements.

2. The Application of [⁶⁸Ga]-Labeled FAPI-04 PET/CT for Targeting and Early Detection of Pancreatic Carcinoma in Patient-Derived Orthotopic Xenograft Models.

3. From Automated Synthesis to In Vivo Application in Multiple Types of Cancer-Clinical Results with [⁶⁸Ga]Ga-DATA^5m.SA.FAPi.