Literature DB >> 33627351

What is the significance of nitrosamine contamination in medicines?

David Erskine1, David Wood2.   

Abstract

Topics for DTB review articles are selected by DTB's editorial board to provide concise overviews of medicines and other treatments to help patients get the best care. Articles include a summary of key points and a brief overview for patients. Articles may also have a series of multiple choice CME questions. © Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  Cardiovascular Diseases; Drug-Related Side Effects and Adverse Reactions; Gastrointestinal diseases

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Year:  2021        PMID： 33627351     DOI： 10.1136/dtb.2020.000036

Source DB:  PubMed          Journal:  Drug Ther Bull        ISSN： 0012-6543


  2 in total

1.  A combination of direct reversion and nucleotide excision repair counters the mutagenic effects of DNA carboxymethylation.

Authors:  Claudia M N Aloisi; Nora A Escher; Hyun Suk Kim; Susanne M Geisen; Gabriele A Fontana; Jung-Eun Yeo; Orlando D Schärer; Shana J Sturla
Journal:  DNA Repair (Amst)       Date:  2021-12-29

2.  Practical and Science-Based Strategy for Establishing Acceptable Intakes for Drug Product N-Nitrosamine Impurities.

Authors:  Krista L Dobo; Michelle O Kenyon; Olivier Dirat; Maria Engel; Andrew Fleetwood; Matthew Martin; Susan Mattano; Alyssa Musso; James Christopher McWilliams; Alexandros Papanikolaou; Patricia Parris; Jessica Whritenour; Shu Yu; Amit S Kalgutkar
Journal:  Chem Res Toxicol       Date:  2022-02-25       Impact factor: 3.739
  2 in total

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