Literature DB >> 33627153

The impact of COVID-19 on the management and outcomes of patients with proximal femoral fractures: a multi-centre study of 580 patients.

Alice Wignall1, Vasileios Giannoudis2, Chiranjit De3, Andrea Jimenez2, Simon Sturdee2, Sohail Nisar4, Hemant Pandit4, Aashish Gulati3, Jeya Palan4.   

Abstract

BACKGROUND: On the 11th March 2020, the World Health Organization declared the COVID-19 outbreak a pandemic. Multiple new guidelines were proposed and existing models of social, domestic and hospital care altered. Most healthcare systems were largely unprepared for this, and the pandemic has tested their adaptability. This study aimed to assess the impact of COVID-19 on the demographics, presentation, clinical management and outcomes of patients with proximal femoral (hip) fractures comparing them to a similar cohort of patients admitted a year earlier.
METHODS: This retrospective multi-centre cohort study compared all patients admitted with hip fractures between 1st March and 30th May 2019 (group PC: pre-COVID-19) with hip fracture patients admitted over the same time period during the pandemic in 2020 (group C: COVID-19). The data was obtained from the hospitals' local and National Hip Fracture Databases. Mortality data was checked with the Office for National Statistics (ONS). Primary outcomes were time to theatre, in-patient length of stay and 30-day mortality.
RESULTS: A total of 580 patients were included (304 group PC, 276 group C). Patient demographics including Charlson Comorbidity Index and Nottingham Hip Fracture Scores were broadly similar across the two cohorts. There was a significant reduction in the percentage of total hip replacements (11 to 5%, p = 0.006) in group C. There was an increase in conservative management (1 to 5%, p = 0.002) in group C. Time to theatre was significantly delayed in group C (43.7 h) vs group PC (34.6 h) (p ≤ 0.001). The overall length of hospital stay was significantly longer in group PC (16.6 days) vs group C (15 days) (p = 0.025). The 30-day mortality rate in group C was 9.8% compared to 8.2% in group PC (p = 0.746), but for COVID-19 (+) patients, it was significantly higher at 38.2% vs 5.8% in COVID-19 (-) patients (p < 0.001).
CONCLUSION: This is one of the largest multi-centre comparative cohort study in the literature to date examining the impact of the COVID-19 pandemic on the management of hip fracture patients. Whilst mortality rates were similar in both groups, COVID-19-positive patients were almost seven times more likely to die, reflecting the seriousness of the COVID-19 infection and its sequelae in such elderly, vulnerable patients.

Entities:  

Keywords:  30-day mortality; COVID-19; Extracapsular hip fracture; Intracapsular hip fracture; Length of stay; Proximal femoral (hip) fracture; Time to theatre

Year:  2021        PMID: 33627153     DOI: 10.1186/s13018-021-02301-z

Source DB:  PubMed          Journal:  J Orthop Surg Res        ISSN: 1749-799X            Impact factor:   2.359


  1 in total

1.  COVID-19 pandemic and hip fractures: impact and lessons learned.

Authors:  Mohamed Arafa; Samia Nesar; Hamza Abu-Jabeh; Ma Odette Remelou Jayme; Yegappan Kalairajah
Journal:  Bone Jt Open       Date:  2020-09-04
  1 in total
  12 in total

1.  COVID-19 Elderly Patients Treated for Proximal Femoral Fractures during the Second Wave of Pandemic in Italy and Iran: A Comparison between Two Countries.

Authors:  Riccardo Giorgino; Erfan Soroush; Sajjad Soroush; Sara Malakouti; Haniyeh Salari; Valeria Vismara; Filippo Migliorini; Riccardo Accetta; Laura Mangiavini
Journal:  Medicina (Kaunas)       Date:  2022-06-09       Impact factor: 2.948

2.  Delayed hospital admission for traumatic hip fractures during the COVID-19 pandemic.

Authors:  Stephanie Jarvis; Kristin Salottolo; Robert Madayag; Jennifer Pekarek; Nnamdi Nwafo; Alexander Wessel; Therese Duane; Zachary Roberts; Mark Lieser; Chad Corrigan; David Bar-Or
Journal:  J Orthop Surg Res       Date:  2021-04-01       Impact factor: 2.359

3.  Mortality escalates in patients of proximal femoral fractures with COVID-19: A systematic review and meta-analysis of 35 studies on 4255 patients.

Authors:  Mohit Kumar Patralekh; Vijay Kumar Jain; Karthikeyan P Iyengar; Gaurav Kumar Upadhyaya; Raju Vaishya
Journal:  J Clin Orthop Trauma       Date:  2021-04-20

4.  COVID-19 among patients with orthopedic surgery: our experience from the Middle East.

Authors:  Abolfazl Bagherifard; Peyman Arasteh; Mostafa Salehpour; Hooman Shariat Zadeh; Farid Najd Mazhar; Hasan Ghandhari; Mohammad Reza Bahaeddini; Pouria Tabrizian; Alireza Askari
Journal:  J Orthop Surg Res       Date:  2021-05-25       Impact factor: 2.359

5.  Hip fracture mortality in patients co-infected with coronavirus disease 2019: a comparison of the first two waves of the United Kingdom pandemic during the pre-vaccine era.

Authors:  Fatima Rashid; David Hawkes; Aatif Mahmood; William James Harrison
Journal:  Int Orthop       Date:  2022-01-09       Impact factor: 3.479

6.  Incidence of hip fractures during the COVID-19 pandemic in the Brazilian public health care system.

Authors:  Audrey Caetano da Silva; Guilherme da Silva Santos; Eliane Mara Cesário Pereira Maluf; Victoria Zeghbi Cochenksi Borba
Journal:  Arch Osteoporos       Date:  2022-03-06       Impact factor: 2.879

7.  Impact of COVID-19 first wave on the in-hospital length of stay of operated proximal femur fracture patients in an industrial hospital in Eastern India.

Authors:  Jayant Kumar; Manoj Kumar Rajak; Anil Kumar Chaudhary; Rajesh Thakur
Journal:  J Family Med Prim Care       Date:  2022-03-10

Review 8.  Orthopaedic, trauma surgery, and Covid-2019 pandemic: clinical panorama and future prospective in Europe.

Authors:  Filippo Migliorini; Christian David Weber; Geatano Pappalardo; Hanno Schenker; Ulf Krister Hofmann; Joerg Eschweiler; Frank Hildebrand
Journal:  Eur J Trauma Emerg Surg       Date:  2022-05-06       Impact factor: 2.374

9.  Impact of COVID-19 on hip fracture care in Ireland: findings from the Irish Hip Fracture Database.

Authors:  Louise Brent; Helena Ferris; Jan Sorensen; Gintare Valentelyte; Fionnola Kelly; Conor Hurson; Emer Ahern
Journal:  Eur Geriatr Med       Date:  2022-01-22       Impact factor: 3.269

10.  The effect of COVID-19 positivity on inflammatory parameters and thirty day mortality rates in patients over sixty five years of age with surgically treated intertrochanteric fractures.

Authors:  Alkan Bayrak; Altuğ Duramaz; Başar Burak Çakmur; Cemal Kural; Serdar Hakan Basaran; Ersin Erçin; Alev Kural; Hüseyin Tamer Ursavaş
Journal:  Int Orthop       Date:  2021-09-01       Impact factor: 3.075

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