Literature DB >> 33625688

Aspirin exacerbated respiratory disease (AERD): molecular and cellular diagnostic & prognostic approaches.

Habib Hybar1, Najmaldin Saki2, Mohsen Maleknia3, Mana Moghaddasi4, Armin Bordbar5, Maliheh Naghavi6.   

Abstract

Aspirin-exacerbated respiratory disease (AERD) is characterized by immune cells dysfunction. This study aimed to investigate the molecular mechanisms involved in AERD pathogenesis. Relevant literatures were identified by a PubMed search (2005-2019) of english language papers using the terms "Aspirin-exacerbated respiratory disease", "Allergic inflammation", "molecular mechanism" and "mutation". According to the significant role of inflammation in AERD development, ILC-2 is known as the most important cell in disease progression. ILC-2 produces cytokines that induce allergic reactions and also cause lipid mediators production, which activates mast cells and basophils, ultimately. Finally, Monoclonal antibody and Aspirin desensitization in patients can be a useful treatment strategy for prevention and treatment.

Entities:  

Keywords:  Allergic inflammation; Aspirin-exacerbated respiratory disease; Molecular mechanism; Mutation

Year:  2021        PMID： 33625688     DOI： 10.1007/s11033-021-06240-0

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN： 0301-4851            Impact factor:   2.316


  33 in total

Review 1.  Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) - classification, diagnosis and management: review of the EAACI/ENDA(#) and GA2LEN/HANNA*.

Authors:  Marek L Kowalski; J S Makowska; M Blanca; S Bavbek; G Bochenek; J Bousquet; P Bousquet; G Celik; P Demoly; E R Gomes; E Niżankowska-Mogilnicka; A Romano; M Sanchez-Borges; M Sanz; M J Torres; A De Weck; A Szczeklik; K Brockow
Journal:  Allergy       Date:  2011-02-14       Impact factor: 13.146

2.  HLA-DRB and HLA-DQ genetic variability in patients with aspirin-exacerbated respiratory disease.

Authors:  Hossein Esmaeilzadeh; Mohammad Nabavi; Ali Akbar Amirzargar; Zahra Aryan; Saba Arshi; Mohammad Hassan Bemanian; Morteza Fallahpour; Negar Mortazavi; Nima Rezaei
Journal:  Am J Rhinol Allergy       Date:  2015 May-Jun       Impact factor: 2.467

3.  Heat shock protein 70 gene polymorphisms in Japanese patients with aspirin-exacerbated respiratory disease.

Authors:  Kiyokazu Kikuchi; Shyuzo Abe; Kazumi Kodaira; Tatsuo Yukawa; Soichiro Hozawa; Hiroyuki Mochizuki; Motohiro Kurosawa
Journal:  J Investig Med       Date:  2013-04       Impact factor: 2.895

4.  Aspirin activation of eosinophils and mast cells: implications in the pathogenesis of aspirin-exacerbated respiratory disease.

Authors:  John W Steinke; Julie Negri; Lixia Liu; Spencer C Payne; Larry Borish
Journal:  J Immunol       Date:  2014-06-02       Impact factor: 5.422

5.  Expression and role of BAG-1 in eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyps.

Authors:  Dong Lin; Hai Lin; Xisheng Xiong
Journal:  Inflammation       Date:  2014-12       Impact factor: 4.092

Review 6.  Pathogenesis of NSAID-induced reactions in aspirin-exacerbated respiratory disease.

Authors:  Tanya M Laidlaw
Journal:  World J Otorhinolaryngol Head Neck Surg       Date:  2018-09-05

Review 7.  A review of the diagnosis, prevention, and treatment methods of inflammatory bowel disease.

Authors:  Seyed Saeid Seyedian; Forogh Nokhostin; Mehrdad Dargahi Malamir
Journal:  J Med Life       Date:  2019 Apr-Jun

8.  Platelet microparticles inhibit IL-17 production by regulatory T cells through P-selectin.

Authors:  Sip Dinkla; Bram van Cranenbroek; Wouter A van der Heijden; Xuehui He; Rike Wallbrecher; Ingrid E Dumitriu; André J van der Ven; Giel J C G M Bosman; Hans J P M Koenen; Irma Joosten
Journal:  Blood       Date:  2016-02-22       Impact factor: 22.113

9.  Cysteinyl leukotriene receptor 2 drives lung immunopathology through a platelet and high mobility box 1-dependent mechanism.

Authors:  Tao Liu; Nora A Barrett; Yoshihide Kanaoka; Kathleen Buchheit; Tanya M Laidlaw; Denise Garofalo; Juying Lai; Howard R Katz; Chunli Feng; Joshua A Boyce
Journal:  Mucosal Immunol       Date:  2019-01-21       Impact factor: 7.313

10.  Chloroquine Treatment Suppresses Mucosal Inflammation in a Mouse Model of Eosinophilic Chronic Rhinosinusitis.

Authors:  Mi Ra Choi; Jun Xu; Seulgi Lee; Sun Hee Yeon; Soo Kyoung Park; Ki Sang Rha; Yong Min Kim
Journal:  Allergy Asthma Immunol Res       Date:  2020-11       Impact factor: 5.764
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  1 in total

Review 1.  The Utility of Nasal Challenges to Phenotype Asthma Patients.

Authors:  Guillermo Bentabol-Ramos; Rocio Saenz de Santa Maria-Garcia; Monica Vidal-Diaz; Ibon Eguiluz-Gracia; Almudena Testera-Montes
Journal:  Int J Mol Sci       Date:  2022-04-27       Impact factor: 6.208
  1 in total

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