Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 MELAS syndrome: characteristic migrainous and epileptic features and maternal transmission.

Literature DB >> 3362373

MELAS syndrome: characteristic migrainous and epileptic features and maternal transmission.

P Montagna¹, R Gallassi, R Medori, E Govoni, M Zeviani, S Di Mauro, E Lugaresi, F Andermann.

Abstract

Severe prolonged migrainous symptoms and prolonged partial status epilepticus are characteristic features of the MELAS syndrome (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes). Maternal transmission previously found in myoclonus epilepsy and ragged-red fibers (MERRF), another mitochondrial disease, is suggested in this disorder as well.

Entities: Disease

Mesh：

Year: 1988 PMID： 3362373 DOI： 10.1212/wnl.38.5.751

Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910

Keyword Cloud
Cited

30 in total

1. The mutant mitochondrial genes in mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) were selectively amplified through generations.

Authors: Y Kobayashi; K Ichihashi; S Ohta; K Nihei; Y Kagawa; M Yanagisawa; M Y Momoi
Journal: J Inherit Metab Dis Date: 1992 Impact factor: 4.982

Review 2. The mitochondrial myopathy encephalopathy, lactic acidosis with stroke-like episodes (MELAS) syndrome: a review of treatment options.

Authors: Fernando Scaglia; Jennifer L Northrop
Journal: CNS Drugs Date: 2006 Impact factor: 5.749

3. Maternally inherited deafness and unusual phenotypic manifestations associated with A3243G mitochondrial DNA mutation.

Authors: Katalin Komlósi; Richárd Kellermayer; Anita Maász; Viktória Havasi; Katalin Hollódy; Olga Vincze; Hajnalka Merkli; Endre Pál; Béla Melegh
Journal: Pathol Oncol Res Date: 2005-07-01 Impact factor: 3.201

4. Migraine as a defect of brain oxidative metabolism: a hypothesis.

Authors: P Montagna; T Sacquegna; P Cortelli; E Lugaresi
Journal: J Neurol Date: 1989-02 Impact factor: 4.849

Review 5. Organelle pathology in metabolic neuromuscular disease: an overview.

Authors: L E Becker
Journal: Can J Vet Res Date: 1990-01 Impact factor: 1.310

6. Lipoic (thioctic) acid increases brain energy availability and skeletal muscle performance as shown by in vivo 31P-MRS in a patient with mitochondrial cytopathy.

Authors: B Barbiroli; R Medori; H J Tritschler; T Klopstock; P Seibel; H Reichmann; S Iotti; R Lodi; P Zaniol
Journal: J Neurol Date: 1995-07 Impact factor: 4.849

MELAS syndrome: characteristic migrainous and epileptic features and maternal transmission.

1. The mutant mitochondrial genes in mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) were selectively amplified through generations.

Review 2. The mitochondrial myopathy encephalopathy, lactic acidosis with stroke-like episodes (MELAS) syndrome: a review of treatment options.

3. Maternally inherited deafness and unusual phenotypic manifestations associated with A3243G mitochondrial DNA mutation.

4. Migraine as a defect of brain oxidative metabolism: a hypothesis.

Review 5. Organelle pathology in metabolic neuromuscular disease: an overview.

6. Lipoic (thioctic) acid increases brain energy availability and skeletal muscle performance as shown by in vivo 31P-MRS in a patient with mitochondrial cytopathy.

7. Epilepsy in a mitochondrial disorder.

8. A MELAS syndrome family harboring two mutations in mitochondrial genome.

9. Case-control study of migraine and risk of ischaemic stroke in young women.

10. Familial and sporadic hemiplegic migraine: diagnosis and treatment.