Yuho Miyamoto1,2, Hirayuki Enomoto3, Hiroki Nishikawa1, Takashi Nishimura1, Yoshinori Iwata1, Shuhei Nishiguchi4, Hiroko Iijima1. 1. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan. 2. Department of Gastroenterology, Takarazuka City Hospital, Hyogo, Japan. 3. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan; enomoto@hyo-med.ac.jp. 4. Department of Gastroenterology, Kano General Hospital, Osaka, Japan.
Abstract
BACKGROUND/AIM: This study aimed to assess the association of the modified albumin-bilirubin (mALBI) grade with the endoscopic findings of gastroesophageal varices (GEVs). PATIENTS AND METHODS: A total of 141 patients with histologically proven cirrhosis who underwent a liver biopsy and esophagogastroduodenoscopy were enrolled. The relationships between the mALBI grade and endoscopic findings were evaluated. RESULTS: The incidence of GEVs and high-risk GEVs differed among mALBI grades. Patients with mALBI grades of 2b-3 had higher rates of GEVs and high-risk GEVs in comparison to those with mALBI grades of 1-2a (p<0.0001). In addition, patients with mALBI grade 2b or grade 3, but not those with mALBI grade 2a, had significantly higher rates of complicated GEVs and high-risk GEVs in comparison to those with mALBI grade 1. CONCLUSION: The mALBI grade may be useful in predicting the presence of GEVs and for stratifying their bleeding risk. Copyright
BACKGROUND/AIM: This study aimed to assess the association of the modified albumin-bilirubin (mALBI) grade with the endoscopic findings of gastroesophageal varices (GEVs). PATIENTS AND METHODS: A total of 141 patients with histologically proven cirrhosis who underwent a liver biopsy and esophagogastroduodenoscopy were enrolled. The relationships between the mALBI grade and endoscopic findings were evaluated. RESULTS: The incidence of GEVs and high-risk GEVs differed among mALBI grades. Patients with mALBI grades of 2b-3 had higher rates of GEVs and high-risk GEVs in comparison to those with mALBI grades of 1-2a (p<0.0001). In addition, patients with mALBI grade 2b or grade 3, but not those with mALBI grade 2a, had significantly higher rates of complicated GEVs and high-risk GEVs in comparison to those with mALBI grade 1. CONCLUSION: The mALBI grade may be useful in predicting the presence of GEVs and for stratifying their bleeding risk. Copyright
Authors: Han Ah Lee; Seung Up Kim; Yeon Seok Seo; Young-Sun Lee; Seong Hee Kang; Young Kul Jung; Moon Young Kim; Ji Hoon Kim; Sang Gyune Kim; Ki Tae Suk; Soung Won Jung; Jae Young Jang; Hyonggin An; Hyung Joon Yim; Soon Ho Um Journal: Liver Int Date: 2019-02-06 Impact factor: 5.828