TomÁs Rodrigues MagalhÃes1, JÉrÔme BenoÎt2, SlavomÍra NÉČovÁ2, Susan North2, Felisbina LuÍsa Queiroga3,4,5. 1. Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro, Vila Real, Portugal. 2. Southfields Veterinary Specialists (formerly VRCC Veterinary Referrals), Essex, U.K. 3. Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro, Vila Real, Portugal; fqueirog@utad.pt. 4. Center for Research and Technology of Agro-Environment and Biological Sciences (CITAB), University of Trás-os-Montes and Alto Douro, Vila Real, Portugal. 5. Center for the Study of Animal Sciences, CECA-ICETA, University of Porto, Porto, Portugal.
Abstract
AIM: To characterize a group of dogs diagnosed with meningioma or glioma treated with radiation therapy and assess the clinical impact of diagnosis and radiation protocol on survival time. PATIENTS AND METHODS: Canine patient records from a single veterinary referral hospital, between 2011 and 2015, were searched for intracranial tumour cases treated with radiation therapy, as a sole modality. Thirty-two dogs were included. RESULTS: Median survival times were 524 days [95% confidence interval (CI)=287-677] in total, 512 days (95% CI=101-682) for the glioma group and 536 days (95% CI=249-677) for the meningioma group. No significant difference in survival was detected when using a definitive or a palliative protocol (p=0.130), nor other prognostic factors were found. CONCLUSION: Our results highlight the efficacy of radiation therapy in the treatment of canine meningioma, as well as glioma, suggesting a change in the current perception of the response of glial tumours to radiation. Copyright
AIM: To characterize a group of dogs diagnosed with meningioma or glioma treated with radiation therapy and assess the clinical impact of diagnosis and radiation protocol on survival time. PATIENTS AND METHODS: Caninepatient records from a single veterinary referral hospital, between 2011 and 2015, were searched for intracranial tumour cases treated with radiation therapy, as a sole modality. Thirty-two dogs were included. RESULTS: Median survival times were 524 days [95% confidence interval (CI)=287-677] in total, 512 days (95% CI=101-682) for the glioma group and 536 days (95% CI=249-677) for the meningioma group. No significant difference in survival was detected when using a definitive or a palliative protocol (p=0.130), nor other prognostic factors were found. CONCLUSION: Our results highlight the efficacy of radiation therapy in the treatment of caninemeningioma, as well as glioma, suggesting a change in the current perception of the response of glial tumours to radiation. Copyright
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