Literature DB >> 33622245

General anaesthesia related mortality in a limited resource settings region: a retrospective study in two teaching hospitals of Butembo.

Furaha Nzanzu Blaise Pascal1,2, Agnes Malisawa3, Andreas Barratt-Due4, Felix Namboya5, Gregor Pollach5.   

Abstract

BACKGROUND: General anaesthesia (GA) in developing countries is still a high-risk practice, especially in Africa, accompanied with high morbidity and mortality. No study has yet been conducted in Butembo in the Democratic Republic of the Congo to determine the mortality related to GA practice. The main objective of this study was to assess mortality related to GA in Butembo.
METHODS: This was a retrospective descriptive and analytic study of patients who underwent surgery under GA in the 2 main teaching hospitals of Butembo from January 2011 to December 2015. Data were collected from patients files, anaesthesia registries and were analysed with SPSS 26.
RESULTS: From a total of 921 patients, 539 (58.5%) were male and 382 (41.5%) female patients. A total of 83 (9.0%) patients died representing an overall perioperative mortality rate of 90 per 1000. Out of the 83 deaths, 38 occurred within 24 h representing GA related mortality of 41 per 1000. There was a global drop in mortality from 2011 to 2015. The risk factors of death were: being a neonate or a senior adult, emergency operation, ASA physical status > 2 and a single deranged vital sign preoperatively, presenting any complication during GA, anaesthesia duration > 120 minutes as well as visceral surgeries/laparotomies. Ketamine was the most employed anaesthetic.
CONCLUSION: GA related mortality is very high in Butembo. Improved GA services and outcomes can be obtained by training more anaesthesia providers, proper patients monitoring, improved infrastructure, better equipment and drugs procurement and considering regional anaesthesia whenever possible.

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Year:  2021        PMID: 33622245      PMCID: PMC7901086          DOI: 10.1186/s12871-021-01280-2

Source DB:  PubMed          Journal:  BMC Anesthesiol        ISSN: 1471-2253            Impact factor:   2.217


  35 in total

1.  A study of the deaths associated with anesthesia and surgery: based on a study of 599, 548 anesthesias in ten institutions 1948-1952, inclusive.

Authors:  H K BEECHER; D P TODD
Journal:  Ann Surg       Date:  1954-07       Impact factor: 12.969

2.  Anesthesia in Africa: quo vadis?

Authors:  P Van Houwe
Journal:  Acta Anaesthesiol Belg       Date:  2007

3.  Drug error in anaesthetic practice: a review of 896 reports from the Australian Incident Monitoring Study database.

Authors:  A Abeysekera; I J Bergman; M T Kluger; T G Short
Journal:  Anaesthesia       Date:  2005-03       Impact factor: 6.955

4.  The burden of surgical conditions and access to surgical care in low- and middle-income countries.

Authors:  Doruk Ozgediz; Dean Jamison; Meena Cherian; Kelly McQueen
Journal:  Bull World Health Organ       Date:  2008-08       Impact factor: 9.408

5.  The rate-limiting step: the provision of safe anesthesia in low-income countries.

Authors:  Simon Hendel; Thomas Coonan; Sarah Thomas; Kelly McQueen
Journal:  World J Surg       Date:  2015-04       Impact factor: 3.352

6.  Complications associated with anaesthesia--a prospective survey in France.

Authors:  L Tiret; J M Desmonts; F Hatton; G Vourc'h
Journal:  Can Anaesth Soc J       Date:  1986-05

7.  Improving Anesthesia Safety in Low-Resource Settings.

Authors:  Fauzia A Khan; Alan F Merry
Journal:  Anesth Analg       Date:  2018-04       Impact factor: 5.108

Review 8.  Perioperative and anaesthetic-related mortality in developed and developing countries: a systematic review and meta-analysis.

Authors:  Daniel Bainbridge; Janet Martin; Miguel Arango; Davy Cheng
Journal:  Lancet       Date:  2012-09-22       Impact factor: 79.321

9.  Analysis of deaths related to anesthesia in the period 1996-2004 from closed claims registered by the Danish Patient Insurance Association.

Authors:  Lars Dahlgaard Hove; Jacob Steinmetz; Jens Krogh Christoffersen; Ann Møller; Jacob Nielsen; Henrik Schmidt
Journal:  Anesthesiology       Date:  2007-04       Impact factor: 7.892

Review 10.  Mortality in anesthesia: a systematic review.

Authors:  Leandro Gobbo Braz; Danilo Gobbo Braz; Deyvid Santos da Cruz; Luciano Augusto Fernandes; Norma Sueli Pinheiro Módolo; José Reinaldo Cerqueira Braz
Journal:  Clinics (Sao Paulo)       Date:  2009       Impact factor: 2.365

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