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Literature DB >> 3362067

19F NMR imaging of blood oxygenation in the brain.

D Eidelberg¹, G Johnson, D Barnes, P S Tofts, D Delpy, D Plummer, W I McDonald.

Abstract

Perfluorocarbon (PFC) emulsions have been developed as oxygen carrying blood substitutes. High fluorine concentrations allow them to be used in 19F NMR imaging of blood vessels. Furthermore, 19F relaxation times in PFCs are dependent on oxygen tension (pO2) so that NMR imaging may provide a noninvasive method of measuring spatially localized pO2 values in vivo. Using these principles, we have formed 19F images and calculated pO2 maps of the cat brain.

Entities: Chemical

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Year: 1988 PMID： 3362067 DOI： 10.1002/mrm.1910060312

Source DB: PubMed Journal: Magn Reson Med ISSN： 0740-3194 Impact factor: 4.668

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Cited

8 in total

Review 1. New frontiers and developing applications in 19F NMR.

Authors: Jian-Xin Yu; Rami R Hallac; Srinivas Chiguru; Ralph P Mason
Journal: Prog Nucl Magn Reson Spectrosc Date: 2012-11-02 Impact factor: 9.795

2. Spatiotemporal mapping of oxygen in a microbially-impacted packed bed using ¹⁹F Nuclear magnetic resonance oximetry.

Authors: Jeffrey W Simkins; Philip S Stewart; Joseph D Seymour
Journal: J Magn Reson Date: 2018-06-22 Impact factor: 2.229

3. An oxygen-consuming phantom simulating perfused tissue to explore oxygen dynamics and (19)F MRI oximetry.

Authors: Steven H Ubert Baete; Jan Vandecasteele; Luc Colman; Wilfried De Neve; Yves De Deene
Journal: MAGMA Date: 2010-06-25 Impact factor: 2.310

4. Non-invasive imaging of oxygen concentration in a complex in vitro biofilm infection model using ¹⁹ F MRI: Persistence of an oxygen sink despite prolonged antibiotic therapy.

Authors: Jeffrey W Simkins; Philip S Stewart; Sarah L Codd; Joseph D Seymour
Journal: Magn Reson Med Date: 2019-08-02 Impact factor: 4.668

8. Rapid quantification of oxygen tension in blood flow with a fluorine nanoparticle reporter and a novel blood flow-enhanced-saturation-recovery sequence.

Authors: Lingzhi Hu; Junjie Chen; Xiaoxia Yang; Shelton D Caruthers; Gregory M Lanza; Samuel A Wickline
Journal: Magn Reson Med Date: 2012-08-22 Impact factor: 4.668

8 in total

19F NMR imaging of blood oxygenation in the brain.

Review 1. New frontiers and developing applications in 19F NMR.

2. Spatiotemporal mapping of oxygen in a microbially-impacted packed bed using ¹⁹F Nuclear magnetic resonance oximetry.

3. An oxygen-consuming phantom simulating perfused tissue to explore oxygen dynamics and (19)F MRI oximetry.

4. Non-invasive imaging of oxygen concentration in a complex in vitro biofilm infection model using ¹⁹ F MRI: Persistence of an oxygen sink despite prolonged antibiotic therapy.

Review 5. In vivo NMR studies of neurodegenerative diseases in transgenic and rodent models.

Review 6. Liquid perfluorocarbons as contrast agents for ultrasonography and (19)F-MRI.

7. Proton imaging of siloxanes to map tissue oxygenation levels (PISTOL): a tool for quantitative tissue oximetry.

8. Rapid quantification of oxygen tension in blood flow with a fluorine nanoparticle reporter and a novel blood flow-enhanced-saturation-recovery sequence.

19F NMR imaging of blood oxygenation in the brain.

Review 1. New frontiers and developing applications in 19F NMR.

2. Spatiotemporal mapping of oxygen in a microbially-impacted packed bed using 19F Nuclear magnetic resonance oximetry.

3. An oxygen-consuming phantom simulating perfused tissue to explore oxygen dynamics and (19)F MRI oximetry.

4. Non-invasive imaging of oxygen concentration in a complex in vitro biofilm infection model using 19 F MRI: Persistence of an oxygen sink despite prolonged antibiotic therapy.

Review 5. In vivo NMR studies of neurodegenerative diseases in transgenic and rodent models.

Review 6. Liquid perfluorocarbons as contrast agents for ultrasonography and (19)F-MRI.

7. Proton imaging of siloxanes to map tissue oxygenation levels (PISTOL): a tool for quantitative tissue oximetry.

8. Rapid quantification of oxygen tension in blood flow with a fluorine nanoparticle reporter and a novel blood flow-enhanced-saturation-recovery sequence.

2. Spatiotemporal mapping of oxygen in a microbially-impacted packed bed using ¹⁹F Nuclear magnetic resonance oximetry.

4. Non-invasive imaging of oxygen concentration in a complex in vitro biofilm infection model using ¹⁹ F MRI: Persistence of an oxygen sink despite prolonged antibiotic therapy.