| Literature DB >> 33619451 |
Laura Trovato1,2, Maddalena Calvo1, Giuseppe Migliorisi1, Marinella Astuto3, Francesco Oliveri3, Salvatore Oliveri1,2.
Abstract
Invasive pulmonary aspergillosis, known as a complication in patients with severe respiratory syndromes, recently showed a correlation with COVID-19 pneumonia, and the clinical characteristics of COVID-19 associated pulmonary aspergillosis (CAPA) have been described. Unfortunately, infections by the Aspergillus genus are often diagnosed in post-mortem time, because of diagnostic delays and a rapid worsening of respiratory conditions. Literature data document, in fact, only few cases of COVID-19 Aspergillus niger coinfection. The aim of this study was to describe a case of a VAP-related probable pulmonary aspergillosis by Aspergillus niger in a COVID-19 patient. Despite the definition of fungal etiology and the rapid administration of antifungal therapy, the patient died while on ventilator support because of severe respiratory impairment.Entities:
Keywords: Aspergillus niger; C-PAP, Continuous Positive Airway Pressure; GM, Aspergillus antigen galactomannan; ICU, Intensive Care Unit; IPA, Invasive pulmonary aspergillosis; SARS-CoV-2; VAP, ventilator associated pneumonia; coinfection; pulmonary aspergillosis; ventilator-associated pneumonia
Year: 2021 PMID： 33619451 PMCID： PMC7890353 DOI： 10.1016/j.rmcr.2021.101367
Source DB: PubMed Journal: Respir Med Case Rep ISSN： 2213-0071