Literature DB >> 33619245

Genome and epigenome editing identify CCR9 and SLC6A20 as target genes at the 3p21.31 locus associated with severe COVID-19.

Yao Yao1,2, Fei Ye3, Kailong Li4, Shuquan Rao5, Peng Xu6, Wenjie Tan3, Quansheng Feng1.   

Abstract

Entities:  

Year:  2021        PMID： 33619245      PMCID： PMC7897877          DOI： 10.1038/s41392-021-00519-1

Source DB:  PubMed          Journal:  Signal Transduct Target Ther        ISSN： 2059-3635


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  12 in total

1.  Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality.

Authors:  Tomoko Nakanishi; Sara Pigazzini; Frauke Degenhardt; Mattia Cordioli; Guillaume Butler-Laporte; Douglas Maya-Miles; Luis Bujanda; Youssef Bouysran; Mari Ek Niemi; Adriana Palom; David Ellinghaus; Atlas Khan; Manuel Martínez-Bueno; Selina Rolker; Sara Amitrano; Luisa Roade Tato; Francesca Fava; Christoph D Spinner; Daniele Prati; David Bernardo; Federico Garcia; Gilles Darcis; Israel Fernández-Cadenas; Jan Cato Holter; Jesus M Banales; Robert Frithiof; Krzysztof Kiryluk; Stefano Duga; Rosanna Asselta; Alexandre C Pereira; Manuel Romero-Gómez; Beatriz Nafría-Jiménez; Johannes R Hov; Isabelle Migeotte; Alessandra Renieri; Anna M Planas; Kerstin U Ludwig; Maria Buti; Souad Rahmouni; Marta E Alarcón-Riquelme; Eva C Schulte; Andre Franke; Tom H Karlsen; Luca Valenti; Hugo Zeberg; J Brent Richards; Andrea Ganna
Journal:  J Clin Invest       Date:  2021-12-01       Impact factor: 14.808

2.  The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses.

Authors:  Yunus Kuijpers; Xiaojing Chu; Martin Jaeger; Simone J C F M Moorlag; Valerie A C M Koeken; Bowen Zhang; Aline de Nooijer; Inge Grondman; Manoj Kumar Gupta; Nico Janssen; Vera P Mourits; L Charlotte J de Bree; Quirijn de Mast; Frank L van de Veerdonk; Leo A B Joosten; Yang Li; Mihai G Netea; Cheng-Jian Xu
Journal:  Front Immunol       Date:  2022-05-12       Impact factor: 8.786

Review 3.  The human genetic epidemiology of COVID-19.

Authors:  Mari E K Niemi; Mark J Daly; Andrea Ganna
Journal:  Nat Rev Genet       Date:  2022-05-02       Impact factor: 59.581

4.  Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus.

Authors:  Amy R Cross; Peng Hua; Damien J Downes; Nigel Roberts; Ron Schwessinger; Antony J Cutler; Altar M Munis; Jill Brown; Olga Mielczarek; Carlos E de Andrea; Ignacio Melero; Deborah R Gill; Stephen C Hyde; Julian C Knight; John A Todd; Stephen N Sansom; Fadi Issa; James O J Davies; Jim R Hughes
Journal:  Nat Genet       Date:  2021-11-04       Impact factor: 38.330

Review 5.  The association of COVID-19 severity and susceptibility and genetic risk factors: A systematic review of the literature.

Authors:  Angela Ishak; Meghana Mehendale; Mousa M AlRawashdeh; Cristina Sestacovschi; Medha Sharath; Krunal Pandav; Sima Marzban
Journal:  Gene       Date:  2022-06-14       Impact factor: 3.913

6.  Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality.

Authors:  Tomoko Nakanishi; Sara Pigazzini; Frauke Degenhardt; Mattia Cordioli; Guillaume Butler-Laporte; Douglas Maya-Miles; Beatriz Nafría-Jiménez; Youssef Bouysran; Mari Niemi; Adriana Palom; David Ellinghaus; Atlas Khan; Manuel Martínez-Bueno; Selina Rolker; Sara Amitano; Luisa Roade Tato; Francesca Fava; Christoph D Spinner; Daniele Prati; David Bernardo; Federico Garcia; Gilles Darcis; Israel Fernández-Cadenas; Jan Cato Holter; Jesus Banales; Robert Frithiof; Krzysztof Kiryluk; Stefano Duga; Rosanna Asselta; Alexandre C Pereira; Manuel Romero-Gómez; Luis Bujanda; Johannes R Hov; Isabelle Migeotte; Alessandra Renieri; Anna M Planas; Kerstin U Ludwig; Maria Buti; Souad Rahmouni; Marta E Alarcón-Riquelme; Eva C Schulte; Andre Franke; Tom H Karlsen; Luca Valenti; Hugo Zeberg; J Brent Richards; Andrea Ganna
Journal:  medRxiv       Date:  2021-03-12

7.  Genetic Loci Associated With COVID-19 Positivity and Hospitalization in White, Black, and Hispanic Veterans of the VA Million Veteran Program.

Authors:  Gina M Peloso; Catherine Tcheandjieu; John E McGeary; Daniel C Posner; Yuk-Lam Ho; Jin J Zhou; Austin T Hilliard; Jacob Joseph; Christopher J O'Donnell; Jimmy T Efird; Dana C Crawford; Wen-Chih Wu; Mehrdad Arjomandi; Yan V Sun; Themistocles L Assimes; Jennifer E Huffman
Journal:  Front Genet       Date:  2022-02-03       Impact factor: 4.599

8.  Integrative transcriptomic, evolutionary, and causal inference framework for region-level analysis: Application to COVID-19.

Authors:  Dan Zhou; Eric R Gamazon
Journal:  NPJ Genom Med       Date:  2022-03-22       Impact factor: 8.617

9.  Severe COVID-19-associated variants linked to chemokine receptor gene control in monocytes and macrophages.

Authors:  Grégoire Stik; Antoinette F van Ouwerkerk; Bernard S Stikker; Lianne Trap; Salvatore Spicuglia; Rudi W Hendriks; Ralph Stadhouders
Journal:  Genome Biol       Date:  2022-04-14       Impact factor: 17.906

Review 10.  COVID-19 metabolism: Mechanisms and therapeutic targets.

Authors:  Tianshi Wang; Ying Cao; Haiyan Zhang; Zihao Wang; Cheuk Him Man; Yunfan Yang; Lingchao Chen; Shuangnian Xu; Xiaojing Yan; Quan Zheng; Yi-Ping Wang
Journal:  MedComm (2020)       Date:  2022-08-09
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