Yiting Chen1, Qian Yang1, Kena Zhao1, Zengqiang Wu2, Xiaoming Shen3, Shenghui Li4,5. 1. School of Public Health, Shanghai Jiao Tong University School of Medicine, 227 South Chongqing Road, Huangpu District, Shanghai, 200025, China. 2. Shanghai Academy of Educational Science, Shanghai, China. 3. MOE-Shanghai Key Laboratory of Children's Environmental Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 4. School of Public Health, Shanghai Jiao Tong University School of Medicine, 227 South Chongqing Road, Huangpu District, Shanghai, 200025, China. lsh9907@163.com. 5. MOE-Shanghai Key Laboratory of Children's Environmental Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China. lsh9907@163.com.
Abstract
BACKGROUND: Adolescence, as a transition between childhood and adulthood, is a critical stage for the long-term control of atopic diseases. We aim to determine if sleep characteristics are involved in the increased risk of atopic disease among adolescents. METHODS: Adopting the stratified cluster random sampling method, this cross-sectional survey included 4932 participants aged 12-18 years. The Chinese version of adolescent sleep disturbance questionnaire and the adolescent sleep hygiene scale were used to collect information on sleep problems and sleep hygiene, respectively. Logistic regression models were implemented to examine the associations of sleep with atopic diseases. RESULTS: Sleep duration was not found to be related with allergic diseases. By contrast, sleep-disordered breathing was associated with an increased risk of asthma (adjusted OR = 1.79, 95% CI 1.25-2.55), allergic rhinitis (adjusted OR = 1.95, 95% CI 1.52-2.49), and eczema (adjusted OR = 1.63, 95% CI 1.23-2.16); poor sleep physiology was correspondent to increased odds of asthma (adjusted OR = 1.69, 95% CI 1.24-2.29), allergic rhinitis (adjusted OR = 1.40, 95% CI 1.13-1.73) and eczema (adjusted OR = 1.66, 95% CI 1.32-2.09); non-optimal sleep environment was associated with an increased prevalence of asthma (adjusted OR = 1.52, 95% CI 1.08-2.12), allergic rhinitis (adjusted OR = 1.32, 95% CI 1.04-1.69) and eczema (adjusted OR = 1.53, 95% CI 1.19-1.96). CONCLUSIONS: As sleep-disordered breathing, poor sleep physiology and non-optimal sleep environment were associated with a higher risk of allergic diseases, the results of this study provide a new concept for the adjuvant treatment of allergic diseases in adolescents. Management strategies of allergic diseases should take regular screening and targeted treatment of sleep issues into account.
BACKGROUND: Adolescence, as a transition between childhood and adulthood, is a critical stage for the long-term control of atopic diseases. We aim to determine if sleep characteristics are involved in the increased risk of atopic disease among adolescents. METHODS: Adopting the stratified cluster random sampling method, this cross-sectional survey included 4932 participants aged 12-18 years. The Chinese version of adolescent sleep disturbance questionnaire and the adolescent sleep hygiene scale were used to collect information on sleep problems and sleep hygiene, respectively. Logistic regression models were implemented to examine the associations of sleep with atopic diseases. RESULTS: Sleep duration was not found to be related with allergic diseases. By contrast, sleep-disordered breathing was associated with an increased risk of asthma (adjusted OR = 1.79, 95% CI 1.25-2.55), allergic rhinitis (adjusted OR = 1.95, 95% CI 1.52-2.49), and eczema (adjusted OR = 1.63, 95% CI 1.23-2.16); poor sleep physiology was correspondent to increased odds of asthma (adjusted OR = 1.69, 95% CI 1.24-2.29), allergic rhinitis (adjusted OR = 1.40, 95% CI 1.13-1.73) and eczema (adjusted OR = 1.66, 95% CI 1.32-2.09); non-optimal sleep environment was associated with an increased prevalence of asthma (adjusted OR = 1.52, 95% CI 1.08-2.12), allergic rhinitis (adjusted OR = 1.32, 95% CI 1.04-1.69) and eczema (adjusted OR = 1.53, 95% CI 1.19-1.96). CONCLUSIONS: As sleep-disordered breathing, poor sleep physiology and non-optimal sleep environment were associated with a higher risk of allergic diseases, the results of this study provide a new concept for the adjuvant treatment of allergic diseases in adolescents. Management strategies of allergic diseases should take regular screening and targeted treatment of sleep issues into account.
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