Literature DB >> 33617964

Saponins: Extraction, bio-medicinal properties and way forward to anti-viral representatives.

Pallavi Sharma1, Arti Tyagi2, Pravin Bhansali3, Shubhra Pareek4, Vineeta Singh5, Ashal Ilyas6, Rajeev Mishra7, Nitesh Kumar Poddar8.   

Abstract

Medicinal or herbal plants are widely used for their many favourable properties and are generally safe without any side effects. Saponins are sugar conjugated natural compounds which possess a multitude of biological activities such as medicinal properties, antimicrobial activity, antiviral activity, etc. Saponin production is a part of the normal growth and development process in a lot of plants and plant extracts such as liquorice and ginseng which are exploited as potential drug sources. Herbal compounds have shown a great potential against a wide variety of infectious agents, including viruses such as the SARS-CoV; these are all-natural products and do not show any adverse side effects. This article reviews the various aspects of saponin biosynthesis and extraction, the need for their integration into more mainstream medicinal therapies and how they could be potentially useful in treating viral diseases such as COVID-19, HIV, HSV, rotavirus etc. The literature presents a close review on the saponin efficacy in targeting mentioned viral diseases that occupy a high mortality rate worldwide. This manuscript indicates the role of saponins as a source of dynamic plant based anti-viral remedies and their various methods for extraction from different sources.
Copyright © 2021 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Anti-Viral; Bio-medicinal; Biosynthesis; Extraction; Herbal drugs; Saponins

Mesh:

Substances:

Year:  2021        PMID: 33617964     DOI: 10.1016/j.fct.2021.112075

Source DB:  PubMed          Journal:  Food Chem Toxicol        ISSN: 0278-6915            Impact factor:   6.023


  4 in total

1.  Ginseng adjuvant therapy on COVID-19: A protocol for systematic review and meta-analysis.

Authors:  Hang Shi; Yawen Xia; Renjun Gu; Shuang Yu
Journal:  Medicine (Baltimore)       Date:  2021-10-29       Impact factor: 1.889

2.  Total Polyphenols Content, Antioxidant and Antimicrobial Activities of Leaves of Solanum elaeagnifolium Cav. from Morocco.

Authors:  Mohammed Bouslamti; Azeddine El Barnossi; Mohammed Kara; Badriyah S Alotaibi; Omkulthom Al Kamaly; Amine Assouguem; Badiaa Lyoussi; Ahmed Samir Benjelloun
Journal:  Molecules       Date:  2022-07-05       Impact factor: 4.927

3.  In Vitro Evaluation of Antimicrobial Effect of Phytobiotics Mixture on Salmonella spp. Isolated from Chicken Broiler.

Authors:  Hubert Iwiński; Karolina Wódz; Karolina Chodkowska; Tomasz Nowak; Henryk Różański
Journal:  Antibiotics (Basel)       Date:  2022-06-28

Review 4.  Withania somnifera (L.) Dunal (Ashwagandha) for the possible therapeutics and clinical management of SARS-CoV-2 infection: Plant-based drug discovery and targeted therapy.

Authors:  Manali Singh; Kuldeep Jayant; Dipti Singh; Shivani Bhutani; Nitesh Kumar Poddar; Anis Ahmad Chaudhary; Salah-Ud-Din Khan; Mohd Adnan; Arif Jamal Siddiqui; Md Imtaiyaz Hassan; Faez Iqbal Khan; Dakun Lai; Shahanavaj Khan
Journal:  Front Cell Infect Microbiol       Date:  2022-08-15       Impact factor: 6.073

  4 in total

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