Krešimir Živković1, Ingrid Marton1,2, Ana Tikvica Luetić1,2, Slavko Gašparov3, Katarina Horvat Pavlov3, Ljudevit Sović4, Anis Cerovac5,6, Dubravko Habek1,2. 1. "Sveti Duh" University Hospital, Department of Obstetrics and Gynecology, University of Zagreb, School of Medicine, Zagreb, Croatia. 2. "Sveti Duh" University Hospital, Department of Obstetrics and Gynecology, Catholic University of Croatia, Zagreb, Croatia. 3. Merkur University Hospital, Department of Pathology and Cytology, University of Zagreb, School of Medicine, Zagreb, Croatia. 4. Department of Pediatric Surgery, Children's Hospital Zagreb, Zagreb, Croatia. 5. Department of Gynecology and Obstetrics, General Hospital Tešanj, Braće Pobrić 17, 74260, Tešanj, Bosnia and Herzegovina. cerovac.anis@gmail.com. 6. Department of Anatomy, University of Tuzla, School of Medicine, Tuzla, Bosnia and Herzegovina. cerovac.anis@gmail.com.
Abstract
BACKGROUND: Ovarian lymphoma is a rare neoplasm and most commonly represents secondary ovarian involvement in overt systemic disease, usually of the non-Hodgkin's type. AIM: To report a case of acute abdomen caused by torquated large ovarian lymphoma. CASE REPORT: We report the case of 65-year-old patient admitted to our hospital with signs and symptoms of acute abdomen. Findings were suggestive of left ovary torsion due to the neoplasm. After detorsion, mobilization, and adhesiolysis, a bilateral adnexectomy was performed. Histopathological and immunohistochemical analysis of the left ovarian tumor was performed and diagnosis of diffuse large B‑cell lymphoma (DLBCL) with a GCB (germinal center B‑cell-like) phenotype was made. Additional bone marrow biopsy and imaging techniques excluded other sites of involvement, confirming diagnosis of primary ovarian DLBCL. CONCLUSION: The prognosis of ovarian lymphomas may be poorer than for other lymphomas because of late diagnosis. The best treatment option appears to be systemic chemotherapy.
BACKGROUND: Ovarian lymphoma is a rare neoplasm and most commonly represents secondary ovarian involvement in overt systemic disease, usually of the non-Hodgkin's type. AIM: To report a case of acute abdomen caused by torquated large ovarian lymphoma. CASE REPORT: We report the case of 65-year-old patient admitted to our hospital with signs and symptoms of acute abdomen. Findings were suggestive of left ovary torsion due to the neoplasm. After detorsion, mobilization, and adhesiolysis, a bilateral adnexectomy was performed. Histopathological and immunohistochemical analysis of the left ovarian tumor was performed and diagnosis of diffuse large B‑cell lymphoma (DLBCL) with a GCB (germinal center B‑cell-like) phenotype was made. Additional bone marrow biopsy and imaging techniques excluded other sites of involvement, confirming diagnosis of primary ovarian DLBCL. CONCLUSION: The prognosis of ovarian lymphomas may be poorer than for other lymphomas because of late diagnosis. The best treatment option appears to be systemic chemotherapy.