Literature DB >> 33614711

Demographic and Clinical Features of 1,641 Patients with Alopecia Areata, Alopecia Totalis, and Alopecia Universalis: A Single-Center Retrospective Study.

Tugba Kevser Uzuncakmak1, Burhan Engin1, Server Serdaroglu1, Yalcin Tuzun1.   

Abstract

BACKGROUND/AIM: Alopecia areata (AA) is a common autoimmune hair disorder which is characterized by noncicatricial hair loss. AA commonly presents with localized patches on the scalp and face but may affect any hair-bearing region of the body leading to even more generalized involvement. AA may affect any age group, gender, and race. The current study investigates the demographic characteristics of the patients with AA and subgroups of AA including alopecia totalis (AT) and alopecia universalis (AU) and the prevalence of disease, sex, and age distribution and seasonal variation retrospectively in a tertiary dermatology clinic in Turkey.
MATERIALS AND METHODS: In this retrospective, cross-sectional study, 1,641 patients diagnosed with AA, AT, and AU in the dermatology clinic of a public university hospital were included. The dermatology outpatient database was reviewed retrospectively. The diagnosis of AA was based on patient history, clinical examinations, and histopathologic findings.
RESULTS: Fifty-four thousand one hundred sixty-eight patients were admitted to our outpatient clinic in 4 years time, and 1,641 were diagnosed as having AA, AT, and AU. One thousand three hundred ninety-two patients (84.8%) had AA, 81 (4.9%) had AT, and 168 (10.2%) had AU. Among the 1,641 patients included in the study, 877 were females (53.4%) and 764 were males (46.6%). The mean age was 29.86 ± 14.48 years in AA, 29.50 ± 16.18 in AT, and 32.81 ± 14.48 in AU; 77.4, 72.8, and 68.5% of patients were aged under 40 years in AA, AT, and AU. There was no statistically significant difference in seasonal presentation times.
CONCLUSION: AA is affecting approximately 2% of the general population without any sex, race, or age group predilection. In this study, we found a lower prevalence of AA in the pediatric age group in comparison with adults. This finding may support the hypothesis of the increasing prevalence of AA over time. The higher ratio of AA regarding this study may support that the frequency of AA and subtypes varies between regions.
Copyright © 2020 by S. Karger AG, Basel.

Entities:  

Keywords:  Alopecia areata; Alopecia totalis; Alopecia universalis; Epidemiology

Year:  2020        PMID: 33614711      PMCID: PMC7879317          DOI: 10.1159/000510880

Source DB:  PubMed          Journal:  Skin Appendage Disord        ISSN: 2296-9160


  19 in total

1.  British Association of Dermatologists' guidelines for the management of alopecia areata 2012.

Authors:  A G Messenger; J McKillop; P Farrant; A J McDonagh; M Sladden
Journal:  Br J Dermatol       Date:  2012-05       Impact factor: 9.302

2.  Alopecia areata prevalence by gender and age.

Authors:  K P Kyriakis; K Paltatzidou; E Kosma; E Sofouri; A Tadros; E Rachioti
Journal:  J Eur Acad Dermatol Venereol       Date:  2008-09-03       Impact factor: 6.166

3.  Epidemiology of alopecia areata, ophiasis, totalis, and universalis: A systematic review and meta-analysis.

Authors:  Harrison H Lee; Eran Gwillim; Kevin R Patel; Tammy Hua; Supriya Rastogi; Erin Ibler; Jonathan I Silverberg
Journal:  J Am Acad Dermatol       Date:  2019-08-19       Impact factor: 11.527

4.  Race and Alopecia Areata amongst US Women.

Authors:  Jordan M Thompson; Min Kyung Park; Abrar A Qureshi; Eunyoung Cho
Journal:  J Investig Dermatol Symp Proc       Date:  2018-01

Review 5.  Treatment of alopecia areata.

Authors:  V C Fiedler; S Alaiti
Journal:  Dermatol Clin       Date:  1996-10       Impact factor: 3.478

6.  Sex- and age-adjusted prevalence estimates of five chronic inflammatory skin diseases in France: results of the « OBJECTIFS PEAU » study.

Authors:  M-A Richard; F Corgibet; M Beylot-Barry; A Barbaud; C Bodemer; V Chaussade; M D'Incan; P Joly; M T Leccia; J M Meurant; A Petit; B Roy Geffroy; J F Sei; C Taieb; L Misery; K Ezzedine
Journal:  J Eur Acad Dermatol Venereol       Date:  2018-07-16       Impact factor: 6.166

7.  Alopecia areata: a long term follow-up study of 191 patients.

Authors:  Antonella Tosti; Sara Bellavista; Matilde Iorizzo
Journal:  J Am Acad Dermatol       Date:  2006-06-27       Impact factor: 11.527

8.  Alopecia areata in Turkey: demographic and clinical features.

Authors:  A Kavak; N Yeşildal; A H Parlak; G Gökdemir; I Aydoğan; H Anul; C Baykal
Journal:  J Eur Acad Dermatol Venereol       Date:  2008-04-01       Impact factor: 6.166

9.  Incidence of alopecia areata in Olmsted County, Minnesota, 1975 through 1989.

Authors:  K H Safavi; S A Muller; V J Suman; A N Moshell; L J Melton
Journal:  Mayo Clin Proc       Date:  1995-07       Impact factor: 7.616

10.  Evaluation of the profile of alopecia areata and the prevalence of thyroid function test abnormalities and serum autoantibodies in Iranian patients.

Authors:  Hassan Seyrafi; Maryam Akhiani; Hamed Abbasi; Sahar Mirpour; Ali Gholamrezanezhad
Journal:  BMC Dermatol       Date:  2005-10-31
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