Constance Carels1, Lucas Wauters2, An Outtier2, Filip Baert3, Peter Bossuyt4, Arnaud Colard5, Danny De Looze6, Marc Ferrante2, Alexander Goegebuer7, Bruno Hauser1, Robert Hilbrands8, Ilse Hoffman9, Bart Keymeulen8, Isabelle Paquot10, Isabelle Ruytjens11, Marc Simoens12, Clara Thienpont13, Annelies Verreth14, Bram Verstockt2, Séverine Vermeire2, Gigi Veereman1. 1. Pediatric Gastroenterology, UZ Brussels, Jette, Belgium. 2. Gastroenterology and Hepatology, University Hospitals, KU Leuven, Leuven, Belgium. 3. Gastroenterology, AZ Delta, Roeselare, Belgium. 4. Gastroenterology, Imelda Ziekenhuis, Bonheiden, Belgium. 5. Gastroenterology, CHC Liège, Liège, Belgium. 6. Gastroenterology and Hepatology, UZ Gent, Ghent, Belgium. 7. Gastroenterology, Heilig Hart Ziekenhuis Leuven, Leuven, Belgium. 8. Diabetes Clinic, UZ Brussel, Jette, Belgium. 9. Pediatric Gastroenterology, University Hospitals, KU Leuven, Leuven, Belgium. 10. Pediatric Gastroenterology, CHC Liège, Liège, Belgium. 11. Gastroenterology, ZNA Middelheim, Antwerp, Belgium. 12. Gastroenterology, ZNA Jan Palfijn, Merksem, Belgium. 13. Gastroenterology, ZNA Stuivenberg, Antwerp, Belgium. 14. Gastroenterology, AZ Sint-Jozef, Malle, Belgium.
Abstract
Background and Aims: The management of chronic inflammatory bowel diseases in youth is challenging. We aimed to determine health literacy (HL), quality of life (QoL) and clinical outcomes in young adults from the BELgian CROhn's disease registry (BELCRO) in comparison to type 1 diabetes mellitus (DM) as a control. Methods: In this prospective and observational study, young adults with Crohn's disease (CD) diagnosed < 18 years and with > 5 years disease duration and a comparable group of patients with DM completed validated HL, QoL and work productivity and activity impairment questionnaires (HLS-EU-Q16, EQ-5D-5L and WPAI). HL was scored as sufficient (13-16), problematic (9-12) or inadequate (0-8). QoL was dichotomized into "no problems" (EQ-5D level 1) or "problems" (EQ-5D levels 2 to 5). Non-parametric (Mann-Whitney U) analyses and Spearman correlations were performed. Results: A total of 52 CD (median [IQR] age of 25.0 [23.8-27.0], 64% male) and 50 DM (age 20.0 [19.0-22.0], 50% male) patients were included. HL was 14.0 [11.0-16.0] for CD and 14.0 [11.3-14.8] for DM (p = 0.6) with similar proportions of sufficient (60 vs. 68%, p = 0.4), problematic (34 vs. 26%, p = 0.3) and inadequate HL (both 6%, p = 1). Although QoL was comparable for CD and DM (77.0 [68.8-82.0] vs. 75.0 [65.0-80.0] %, p =0.4), CD had a trend for higher pain/discomfort (50 vs. 32%, p = 0.06). HL and QoL correlated in CD (r = 0.6, p < 0.001) and DM patients (r = 0.6, p < 0.001). Fewer CD patients with recent hospitalization/surgery had sufficient HL (31 vs. 69%, p = 0.01) and had lower QoL (70.0 [60.0-77.0] vs. 80.0 [70.0-85.0], p = 0.04) compared to those without. Conclusions: Selected young Belgian adults suffering from CD for >5 years have similar and sufficient HL compared to DM patients. However, CD patients requiring hospitalization/surgery have lower HL, which indicates the need for targeted educational programs.
Background and Aims: The management of chronic inflammatory bowel diseases in youth is challenging. We aimed to determine health literacy (HL), quality of life (QoL) and clinical outcomes in young adults from the BELgian CROhn's disease registry (BELCRO) in comparison to type 1 diabetes mellitus (DM) as a control. Methods: In this prospective and observational study, young adults with Crohn's disease (CD) diagnosed < 18 years and with > 5 years disease duration and a comparable group of patients with DM completed validated HL, QoL and work productivity and activity impairment questionnaires (HLS-EU-Q16, EQ-5D-5L and WPAI). HL was scored as sufficient (13-16), problematic (9-12) or inadequate (0-8). QoL was dichotomized into "no problems" (EQ-5D level 1) or "problems" (EQ-5D levels 2 to 5). Non-parametric (Mann-Whitney U) analyses and Spearman correlations were performed. Results: A total of 52 CD (median [IQR] age of 25.0 [23.8-27.0], 64% male) and 50 DM (age 20.0 [19.0-22.0], 50% male) patients were included. HL was 14.0 [11.0-16.0] for CD and 14.0 [11.3-14.8] for DM (p = 0.6) with similar proportions of sufficient (60 vs. 68%, p = 0.4), problematic (34 vs. 26%, p = 0.3) and inadequate HL (both 6%, p = 1). Although QoL was comparable for CD and DM (77.0 [68.8-82.0] vs. 75.0 [65.0-80.0] %, p =0.4), CD had a trend for higher pain/discomfort (50 vs. 32%, p = 0.06). HL and QoL correlated in CD (r = 0.6, p < 0.001) and DMpatients (r = 0.6, p < 0.001). Fewer CD patients with recent hospitalization/surgery had sufficient HL (31 vs. 69%, p = 0.01) and had lower QoL (70.0 [60.0-77.0] vs. 80.0 [70.0-85.0], p = 0.04) compared to those without. Conclusions: Selected young Belgian adults suffering from CD for >5 years have similar and sufficient HL compared to DMpatients. However, CD patients requiring hospitalization/surgery have lower HL, which indicates the need for targeted educational programs.
Authors: Chiara Rosso; Alami Aroussi Aaron; Angelo Armandi; Gian Paolo Caviglia; Marta Vernero; Giorgio Maria Saracco; Marco Astegiano; Elisabetta Bugianesi; Davide Giuseppe Ribaldone Journal: Nurs Rep Date: 2021-04-01