Literature DB >> 33614265

The Slavcleft: a three-center study of the outcome of treatment of cleft lip and palate. Nasolabial appearance.

Adam Stebel1,2, Wanda Urbanová3, Irena Klimova4, Andrzej Brudnicki5, Ivana Dubovska6, Petra Polackova3,6, Daniela Kroupová4, Magdalena Koťová3,6, Piotr S Fudalej6,7,8.   

Abstract

BACKGROUND: There is a multitude of protocols of treatment of cleft lip and palate (CLP) worldwide differing in number of operations, surgical techniques, and timings of surgeries. Despite, facial appearance in subjects with CLP is rarely ideal and residual stigmata are easy to notice in many patients irrespective of the protocol. The prospective controlled investigations are optimal for comparing effectiveness of treatment protocols. Because prospective studies are very challenging to perform in CLP field, it is reasonable to retrospectively assess different surgical protocols to identify the promising ones and then to test them in a prospective way.
METHODS: Our objective was to assess the nasolabial appearance in a preadolescent Slavic population with unilateral cleft lip and palate (UCLP) by using the 0-200 numeric scale with reference photographs. Patients treated in Warsaw, Poland (n = 32), Prague, Czech Republic (n = 26) and Bratislava, Slovakia (n = 17) were included in this retrospective study. Each cleft center used a unique surgical protocol. Two panels of professional raters (n = 7) and laypeople (n = 10) scored blindly the nasolabial esthetics on cropped frontal and profile images with cropped reference photograph present on the same slide. Intra- and inter-rater agreement was assessed with Cronbach's alpha, intraclass correlation coefficients, t-tests, and Bland-Altman plots. Inter-group differences were evaluated with one-way ANOVA and regression analysis.
RESULTS: The agreement within and between raters was acceptable. We found that patients treated in Warsaw, Prague, and Bratislava showed comparable nasolabial appearance on frontal and profile photographs when judged by both professional raters (p > 0.05) and laypeople (p > 0.05). Regression analysis did not identify influence of gender, group (i.e., Warsaw, Prague, and Bratislava), age at lip repair, surgeon, and age at photographic assessment on esthetic outcome (p > 0.05).
CONCLUSION: This study showed that none of the surgical protocols showed superiority to produce good nasolabial appearance.
© 2021 Stebel et al.

Entities:  

Keywords:  Cleft lip and palate; Esthetics; Nasolabial appearance; Slavs

Year:  2021        PMID: 33614265      PMCID: PMC7879938          DOI: 10.7717/peerj.10631

Source DB:  PubMed          Journal:  PeerJ        ISSN: 2167-8359            Impact factor:   2.984


  23 in total

Review 1.  Outcomes in facial aesthetics in cleft lip and palate surgery: a systematic review.

Authors:  V P Sharma; H Bella; M M Cadier; R W Pigott; T E E Goodacre; B M Richard
Journal:  J Plast Reconstr Aesthet Surg       Date:  2012-05-15       Impact factor: 2.740

2.  Comparison of Three Methods of Rating Nasolabial Appearance in Cleft Lip and Palate.

Authors:  Sylwia A Fudalej; Dries Desmedt; Ewald Bronkhorst; Piotr S Fudalej
Journal:  Cleft Palate Craniofac J       Date:  2017-01-31

3.  Facial aesthetics and perceived need for further treatment among adults with repaired cleft as assessed by cleft team professionals and laypersons.

Authors:  Peter Foo; Wayne Sampson; Rachel Roberts; Lisa Jamieson; David David
Journal:  Eur J Orthod       Date:  2011-11-02       Impact factor: 3.075

4.  The Americleft study: an inter-center study of treatment outcomes for patients with unilateral cleft lip and palate part 5. General discussion and conclusions.

Authors:  Kathleen Russell; Ross E Long; Ronald Hathaway; John Daskalogiannakis; Ana Mercado; Marilyn Cohen; Gunvor Semb; William Shaw
Journal:  Cleft Palate Craniofac J       Date:  2011-01-10

5.  The Americleft study: an inter-center study of treatment outcomes for patients with unilateral cleft lip and palate part 4. Nasolabial aesthetics.

Authors:  Ana Mercado; Kathleen Russell; Ronald Hathaway; John Daskalogiannakis; Hani Sadek; Ross E Long; Marilyn Cohen; Gunvor Semb; William Shaw
Journal:  Cleft Palate Craniofac J       Date:  2011-01-10

6.  The Eurocleft study: intercenter study of treatment outcome in patients with complete cleft lip and palate. Part 4: relationship among treatment outcome, patient/parent satisfaction, and the burden of care.

Authors:  Gunvor Semb; Viveca Brattström; Kirsten Mølsted; Birte Prahl-Andersen; Petra Zuurbier; Nichola Rumsey; William C Shaw
Journal:  Cleft Palate Craniofac J       Date:  2005-01

7.  The Eurocleft study: intercenter study of treatment outcome in patients with complete cleft lip and palate. Part 2: craniofacial form and nasolabial appearance.

Authors:  Viveca Brattström; Kirsten Mølsted; Birte Prahl-Andersen; Gunvor Semb; William C Shaw
Journal:  Cleft Palate Craniofac J       Date:  2005-01

8.  Facial esthetics in children with unilateral cleft lip and palate 3 years after alveolar bonegrafting combined with rhinoplasty between 2 and 4 years of age.

Authors:  B Offert; J Janiszewska-Olszowska; Z Dudkiewicz; A Brudnicki; C Katsaros; P S Fudalej
Journal:  Orthod Craniofac Res       Date:  2012-09-17       Impact factor: 1.826

9.  Effect of infant orthopedics on facial appearance of toddlers with complete unilateral cleft lip and palate (Dutchcleft).

Authors:  Catharina A M Bongaarts; Birte Prahl-Andersen; Ewald M Bronkhorst; Paul H M Spauwen; Jan W Mulder; J Michiel Vaandrager; Anne M Kuijpers-Jagtman
Journal:  Cleft Palate Craniofac J       Date:  2008-07

10.  Dentofacial self-perception and social perception of adults with unilateral cleft lip and palate.

Authors:  Philipp Meyer-Marcotty; Angelika Stellzig-Eisenhauer
Journal:  J Orofac Orthop       Date:  2009-05-31       Impact factor: 1.938

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