Literature DB >> 33613813

Acute Effect of Acupuncture on Glycemic Control in Type 2 Diabetes Measured by Continuous Glucose Monitoring: A Pilot Study.

Sérgio Vencio1,2, Isabela Caiado-Vencio3, Adriana Caiado4, Douglas Morgental4, Luisa Soares Dantas5, Rafael Caiado-Vencio6.   

Abstract

Introduction: Acupuncture is a widely used technique for the treatment of diabetes in Asian countries. Nevertheless, there are few studies with appropriate methodological rigor evaluating its effectiveness and promoting a standardized procedure in the Western World.
Objectives: Evaluate the short-term effect of acupuncture in the treatment of type 2 diabetes mellitus (DM2) using continuous glucose monitoring (CGM).
Methods: In a randomized controlled prospective open-label study, we assigned 20 insulin-independent DM2 patients to undergo acupuncture (group 1) or control group (group 2). Participants underwent CGM for 14 days. In group 1, all patients were submitted to acupuncture 4, 8, and 12 days after installation of the monitoring system. Diabetes-specific treatment points were used in all patients (bladder 38, large intestine 4, kidney 24, stomach 36, and spleen 9). This study was approved by the ethics committee (CAAE-60576616.6.0000.5572).
Results: There were no statistically significant differences in the baseline characteristics. In group 1, mean glucose level obtained through 14 days monitoring after acupuncture treatment was 143 ± 28.8 mg/dL, whereas in group 2, who did not receive acupuncture, the mean level was 165.8 ± 30.2 mg/dL (P = 0.015).
Conclusion: In this randomized pilot study, there was an improvement in global glycemic control during the 14-day monitoring in the acupuncture group. Further studies with larger cohorts over a more extended period of time are needed. Clinical Trials: RBR-3m45y3. Copyright 2021, Mary Ann Liebert, Inc., publishers.

Entities:  

Keywords:  acupuncture; diabetes; glucose monitoring

Year:  2021        PMID: 33613813      PMCID: PMC7894033          DOI: 10.1089/acu.2020.1457

Source DB:  PubMed          Journal:  Med Acupunct        ISSN: 1933-6586


  22 in total

1.  Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes.

Authors:  David M Nathan; Patricia A Cleary; Jye-Yu C Backlund; Saul M Genuth; John M Lachin; Trevor J Orchard; Philip Raskin; Bernard Zinman
Journal:  N Engl J Med       Date:  2005-12-22       Impact factor: 91.245

Review 2.  Acupuncture for obesity: a systematic review and meta-analysis.

Authors:  S-H Cho; J-S Lee; L Thabane; J Lee
Journal:  Int J Obes (Lond)       Date:  2009-01-13       Impact factor: 5.095

Review 3.  Acupuncture: is it effective for treatment of insulin resistance?

Authors:  F Liang; D Koya
Journal:  Diabetes Obes Metab       Date:  2010-07       Impact factor: 6.577

4.  An insulin-dependent hypoglycaemia induced by electroacupuncture at the Zhongwan (CV12) acupoint in diabetic rats.

Authors:  S L Chang; J G Lin; T C Chi; I M Liu; J T Cheng
Journal:  Diabetologia       Date:  1999-02       Impact factor: 10.122

5.  10-year follow-up of intensive glucose control in type 2 diabetes.

Authors:  Rury R Holman; Sanjoy K Paul; M Angelyn Bethel; David R Matthews; H Andrew W Neil
Journal:  N Engl J Med       Date:  2008-09-10       Impact factor: 91.245

6.  The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus.

Authors:  D M Nathan; S Genuth; J Lachin; P Cleary; O Crofford; M Davis; L Rand; C Siebert
Journal:  N Engl J Med       Date:  1993-09-30       Impact factor: 91.245

7.  Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group.

Authors: 
Journal:  Lancet       Date:  1998-09-12       Impact factor: 79.321

Review 8.  Treatment of insulin resistance by acupuncture: a review of human and animal studies.

Authors:  Bridget Martinez; Philip V Peplow
Journal:  Acupunct Med       Date:  2016-06-02       Impact factor: 2.267

9.  Acupuncture Alters Expression of Insulin Signaling Related Molecules and Improves Insulin Resistance in OLETF Rats.

Authors:  Xin-Yu Huang; Liang Zhang; Jian Sun; Neng-Gui Xu; Wei Yi
Journal:  Evid Based Complement Alternat Med       Date:  2016-09-22       Impact factor: 2.629

10.  Acute effect of electroacupuncture at the Zusanli acupoints on decreasing insulin resistance as shown by lowering plasma free fatty acid levels in steroid-background male rats.

Authors:  Rong-Tsung Lin; Chung-Yuh Tzeng; Yu-Chen Lee; Wai-Jane Ho; Juei-Tang Cheng; Jaung-Geng Lin; Shih-Liang Chang
Journal:  BMC Complement Altern Med       Date:  2009-08-01       Impact factor: 3.659

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