Shangqing Ren1, Hualin Feng1, Yige Bao2, Yi Wei1, Yong Ou1, Yaoqian Wang1, Qian Lv1, Shan Zhong3, Fang Zhou1, Shida Fan1, Qiang Wang1, Cheng Luo1, Zhengjun Chen1, Yu Nie1, Dong Wang4. 1. Department of Robotic Minimally Invasive Surgery Center, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, No. 32 West Second Section First Ring Road, Chengdu, Sichuan, China. 2. Departments of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China. 3. Department of Organ Transplantation Center, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan, China. 4. Department of Robotic Minimally Invasive Surgery Center, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, No. 32 West Second Section First Ring Road, Chengdu, Sichuan, China. wangdong_robot@163.com.
Abstract
BACKGROUND: Upper urinary tract urothelial carcinoma (UTUC) with multiple pathological types is extremely rare in the clinic, but the recurrence rate and mortality these patients are high. At present, there is no standard treatment for such cases. CASE PRESENTATION: We reported a case of ureteral urothelial carcinoma with squamous cell carcinoma and sarcomatoid carcinoma differentiation and rapid ileal metastasis and reviewed the literature related to different pathological types of upper urinary tract tumours to explore the diagnosis, treatment and prognosis characteristics of the disease, enhance our understanding of its clinical manifestations and history of evolution and provide guidance for avoiding missed diagnosis and misdiagnosis. CONCLUSION: There is no standard treatment for urinary malignant tumours with multiple pathological types; radical surgery is considered a suitable choice. Chemotherapy, targeted drug therapy and immunotherapy may be beneficial to the survival of patients. In short, these patients have a high risk of recurrence and metastasis and a poor prognosis.
BACKGROUND:Upper urinary tract urothelial carcinoma (UTUC) with multiple pathological types is extremely rare in the clinic, but the recurrence rate and mortality these patients are high. At present, there is no standard treatment for such cases. CASE PRESENTATION: We reported a case of ureteral urothelial carcinoma with squamous cell carcinoma and sarcomatoid carcinoma differentiation and rapid ileal metastasis and reviewed the literature related to different pathological types of upper urinary tract tumours to explore the diagnosis, treatment and prognosis characteristics of the disease, enhance our understanding of its clinical manifestations and history of evolution and provide guidance for avoiding missed diagnosis and misdiagnosis. CONCLUSION: There is no standard treatment for urinary malignant tumours with multiple pathological types; radical surgery is considered a suitable choice. Chemotherapy, targeted drug therapy and immunotherapy may be beneficial to the survival of patients. In short, these patients have a high risk of recurrence and metastasis and a poor prognosis.
Authors: Thomas J Walton; Giacomo Novara; Kazumasa Matsumoto; Wassim Kassouf; Hans-Martin Fritsche; Walter Artibani; Patrick J Bastian; Juan I Martínez-Salamanca; Christian Seitz; Stephen A Thomas; Vincenzo Ficarra; Maximilian Burger; Stefan Tritschler; Pierre I Karakiewicz; Shahrokh F Shariat Journal: BJU Int Date: 2010-11-15 Impact factor: 5.588
Authors: Morgan Rouprêt; Marko Babjuk; Eva Compérat; Richard Zigeuner; Richard J Sylvester; Maximilian Burger; Nigel C Cowan; Paolo Gontero; Bas W G Van Rhijn; A Hugh Mostafid; Joan Palou; Shahrokh F Shariat Journal: Eur Urol Date: 2017-09-01 Impact factor: 20.096