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Literature DB >> 3361161

Antioxidants to treat chronic pancreatitis in childhood? Case report and possible implications for pathogenesis.

Abstract

The case history of a 10-yr old boy with calcific chronic pancreatitis is reported. His theophylline clearance of 450 ml/kg/h was several times higher than normal, indicating induction of cytochromes P450. Painful attacks disappeared concurrently with administration of antioxidants. The possible relevance of these findings is discussed in the context of chronic pancreatitis in childhood.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1988 PMID： 3361161 DOI： 10.1007/BF02798933

Source DB: PubMed Journal: Int J Pancreatol ISSN： 0169-4197

18 in total

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Authors: J R Idle; R L Smith
Journal: Drug Metab Rev Date: 1979 Impact factor: 4.518

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Authors: J R Powell; J F Thiercelin; S Vozeh; L Sansom; S Riegelman
Journal: Am Rev Respir Dis Date: 1977-07

3. H2 receptor antagonists, cytochrome P450, and paracetamol-induced hepatotoxicity.

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Journal: Lancet Date: 1985-10-19 Impact factor: 79.321

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Journal: Cancer Res Date: 1981-04 Impact factor: 12.701

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Authors: J M Braganza; G H Kay; V A Tetlow; K J Herman
Journal: Clin Chim Acta Date: 1983-06-15 Impact factor: 3.786

6. Comparative radiological and morphological study of human pancreas.

Authors: J M Braganza; D W Acheson
Journal: Gut Date: 1985-10 Impact factor: 23.059

Review 7. Interactions between ethanol and other hepatotoxic agents.

Authors: O Strubelt
Journal: Biochem Pharmacol Date: 1980-06-01 Impact factor: 5.858

8. Induction of cytochromes P-450 in pancreatic disease: consequence, coincidence or cause?

Authors: D W Acheson; P Rose; J B Houston; J M Braganza
Journal: Clin Chim Acta Date: 1985-12-13 Impact factor: 3.786

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Authors: J W Georgitis; H Eigen; R Warner; M A Gonzales
Journal: Ann Allergy Date: 1982-03

Review 10. Drug-induced hepatotoxicity.

Authors: N Kaplowitz; T Y Aw; F R Simon; A Stolz
Journal: Ann Intern Med Date: 1986-06 Impact factor: 25.391

6 in total

Review 1. Chronic pancreatitis in branched-chain organic acidurias--a case of methylmalonic aciduria and an overview of the literature.

Authors: Jan Marquard; Tarik El Scheich; Dirk Klee; Marcus Schmitt; Thomas Meissner; Ertan Mayatepek; Jun Oh
Journal: Eur J Pediatr Date: 2010-10-06 Impact factor: 3.183

2. Combined antioxidant therapy reduces pain and improves quality of life in chronic pancreatitis.

Authors: Gareth R Kirk; Jonathan S White; Lloyd McKie; Mike Stevenson; Ian Young; W D Barry Clements; Brian J Rowlands
Journal: J Gastrointest Surg Date: 2006-04 Impact factor: 3.452

Review 3. Involvement of free radicals in the pathophysiology of chronic pancreatitis: potential of treatment with antioxidant and scavenger substances.

Authors: C Niederau; H U Schultz; G Letko
Journal: Klin Wochenschr Date: 1991-12-15