| Literature DB >> 33608656 |
Carl Weidinger1,2, Ahmed Nabil Hegazy1,2,3, Rainer Glauben1, Britta Siegmund4.
Abstract
Viral infections with SARS-CoV-2 can cause a multi-facetted disease, which is not only characterized by pneumonia and overwhelming systemic inflammatory immune responses, but which can also directly affect the digestive system and infect intestinal epithelial cells. Here, we review the current understanding of intestinal tropism of SARS-CoV-2 infection, its impact on mucosal function and immunology and summarize the effect of immune-suppression in patients with inflammatory bowel disease (IBD) on disease outcome of COVID-19 and discuss IBD-relevant implications for the clinical management of SARS-CoV-2 infected individuals.Entities:
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Year: 2021 PMID: 33608656 PMCID: PMC7893623 DOI: 10.1038/s41385-021-00384-9
Source DB: PubMed Journal: Mucosal Immunol ISSN: 1933-0219 Impact factor: 7.313