Literature DB >> 33607982

Safe and effective performance of pediatric spinal deformity surgery in patients unwilling to accept blood transfusion: a clinical study and review of literature.

Alexander Mihas1, Subaraman Ramchandran2, Sebastian Rivera3, Ali Mansour4, Jahangir Asghar5, Harry Shufflebarger6, Stephen George4.   

Abstract

BACKGROUND: Pediatric deformity surgery traditionally involves major blood loss. Patients refusing blood transfusion add extra clinical and medicolegal challenges; specifically the Jehovah's witnesses population. The objective of this study is to review the safety and effectiveness of blood conservation techniques in patients undergoing pediatric spine deformity surgery who refuse blood transfusion.
METHODS: After obtaining institutional review board approval, we retrospectively reviewed 20 consecutive patients who underwent spinal deformity surgery and refused blood transfusion at a single institution between 2014 and 2018. We collected pertinent preoperative, intraoperative and most recent clinical and radiological data with latest follow-up (minimum two-year follow-up).
RESULTS: Twenty patients (13 females) with a mean age of 14.1 years were identified. The type of scoliotic deformities were adolescent idiopathic (14), juvenile idiopathic (1), neuromuscular (3) and congenital (2). The major coronal Cobb angle was corrected from 55.4° to 11.2° (80% correction, p <  0.001) at the latest follow-up. A mean of 11.4 levels were fused and 5.6 levels of Pontes osteotomies were performed. One patient underwent L1 hemivertebra resection and three patients had fusion to pelvis. Estimated blood loss, percent estimated blood volume loss, and cell saver returned averaged 307.9 mL, 8.5%, and 80 mL, respectively. Average operative time was 214 min. The average drop in hemoglobin after surgery was 2.9 g/dL. The length of hospital stay averaged 5.1 days. There were no intraoperative complications. Three postoperative complications were identified, none related to their refusal of transfusion. One patient had in-hospital respiratory complication, one patient developed a late infection, and one patient developed asymptomatic radiographic distal junctional kyphosis.
CONCLUSIONS: Blood conservation techniques allow for safe and effective spine deformity surgery in pediatric patients refusing blood transfusion without major anesthetic or medical complications, when performed by an experienced multidisciplinary team. LEVEL OF EVIDENCE: Level IV.

Entities:  

Keywords:  Blood loss; Blood salvage; Blood transfusion; Jehovah’s witness; Scoliosis; Spinal deformity correction

Mesh:

Year:  2021        PMID: 33607982      PMCID: PMC7896412          DOI: 10.1186/s12891-021-04081-3

Source DB:  PubMed          Journal:  BMC Musculoskelet Disord        ISSN: 1471-2474            Impact factor:   2.362


  47 in total

1.  Does the intraoperative tranexamic acid decrease operative blood loss during posterior spinal fusion for treatment of adolescent idiopathic scoliosis?

Authors:  Mitsuru Yagi; Jun Hasegawa; Narihito Nagoshi; Shingo Iizuka; Shinjiro Kaneko; Kentaro Fukuda; Masakazu Takemitsu; Masanobu Shioda; Masafumi Machida
Journal:  Spine (Phila Pa 1976)       Date:  2012-10-01       Impact factor: 3.468

2.  Painted into a corner: unexpected complications in treating a Jehovah's Witness.

Authors:  James W Jones; Laurence B McCullough; Bruce W Richman
Journal:  J Vasc Surg       Date:  2006-07-11       Impact factor: 4.268

3.  The effect of blood transfusion on short-term, perioperative outcomes in elective spine surgery.

Authors:  Andreea Seicean; Nima Alan; Sinziana Seicean; Duncan Neuhauser; Robert J Weil
Journal:  J Clin Neurosci       Date:  2014-05-19       Impact factor: 1.961

Review 4.  Perioperative blood transfusions in orthopaedic surgery.

Authors:  Karthikeyan E Ponnusamy; Thomas J Kim; Harpal S Khanuja
Journal:  J Bone Joint Surg Am       Date:  2014-11-05       Impact factor: 5.284

5.  Blood transfusion in the surgical treatment of adolescent idiopathic scoliosis-a single-center experience of patient blood management in 210 cases.

Authors:  Søren Ohrt-Nissen; Naeem Bukhari; Casper Dragsted; Martin Gehrchen; Pär I Johansson; Jesper Dirks; Jakob Stensballe; Benny Dahl
Journal:  Transfusion       Date:  2017-05-12       Impact factor: 3.157

6.  Preanesthetic Assessment of the Jehovah's Witness Patient.

Authors:  Eric S Lin; Alan D Kaye; Amir R Baluch
Journal:  Ochsner J       Date:  2012

Review 7.  Blood transfusion risks and alternative strategies in pediatric patients.

Authors:  Josée Lavoie
Journal:  Paediatr Anaesth       Date:  2011-01       Impact factor: 2.556

Review 8.  Blood loss in pediatric spine surgery.

Authors:  Frederic Shapiro; Navil Sethna
Journal:  Eur Spine J       Date:  2004-08-13       Impact factor: 3.134

9.  The incidence and risk factors for perioperative allogeneic blood transfusion in primary idiopathic scoliosis surgery.

Authors:  Tyler R Mange; Daniel J Sucato; Kiley F Poppino; Chan-Hee Jo; Brandon R Ramo
Journal:  Spine Deform       Date:  2020-03-09

10.  Quantifying risk of transfusion in children undergoing spine surgery.

Authors:  Michael G Vitale; Douglas E Levy; Maxwell C Park; Hyunok Choi; Julie C Choe; David P Roye
Journal:  Spine J       Date:  2002 May-Jun       Impact factor: 4.166

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.