Literature DB >> 33607847

Successful conservative treatment of placenta accreta with traditional Chinese medicine: A case report.

Huamin Huang1, Jialin Wang2, Keqin Li3, Hongbo Ma3.   

Abstract

RATIONALE: Currently, placenta accreta treatment mainly includes nonconservative surgical and conservative treatments such as Traditional Chinese medicine (TCM). This report describes the case of a 37-year-old woman who suffered incomplete placenta accreta after vaginal delivery and was cured by TCM. TCM treatment of placenta accreta has its own unique advantages, including low toxicity and few side effects, unaffected breastfeeding, and retention of the uterus, which can ensure the expulsion of residual placenta and be beneficial to patients' physical and mental health. PATIENT CONCERNS: Symptoms included a small amount of vaginal bleeding and occasional lesser abdominal pain. The patient showed lesser abdominal tenderness, a red tongue moss with petechial hemorrhage, and a hesitant pulse. The reproductive history was G3P2L2A1. In addition, the patient was afraid of having her uterus removed due to incomplete placental separation. DIAGNOSES: The case was diagnosed as placental accreta. Ultrasound is the preferred method of diagnosis, and biomarkers, such as beta hCG, assist in screening for placental accreta. Doppler ultrasonography showed that in the bottom of the right uterine cavity, there was an uneven echo group of 7.6 × 4.6 cm, which was not clearly demarcated from the posterior wall; the muscle layer became thinner, with a thinnest part of 0.19 cm, and abundant blood flow signals were observed (Fig. 1JOURNAL/medi/04.03/00005792-202102190-00086/figure1/v/2021-02-16T234818Z/r/image-tiff). The beta hCG was 580.92 mIu/ml.
INTERVENTIONS: The patient initially underwent curettage therapy 9 days after delivery, but it failed due to excessive intraoperative bleeding. The patient then turned to TCM treatment. The doctor prescribed a multi-herbal formula. OUTCOMES: After 4 months, the residual placenta was expelled, and the patient's symptoms disappeared completely. No adverse and unexpected events occurred during treatment. During 3 months of follow-up, the patient had no abdominal pain, abnormal vaginal bleeding, or other complications. LESSONS: This study shows that TCM is safe and effective for treating placenta accreta, and it is worth recommending TCM as a conservative treatment along with other treatments. In practice, however, we find that the earlier TCM treatment is applied, the better the effect; therefore, early intervention with TCM is particularly important.
Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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Year:  2021        PMID: 33607847      PMCID: PMC7899819          DOI: 10.1097/MD.0000000000024820

Source DB:  PubMed          Journal:  Medicine (Baltimore)        ISSN: 0025-7974            Impact factor:   1.817


  10 in total

Review 1.  Placenta accreta spectrum: accreta, increta, and percreta.

Authors:  Robert M Silver; Kelli D Barbour
Journal:  Obstet Gynecol Clin North Am       Date:  2015-06       Impact factor: 2.844

2.  Placenta Praevia and Placenta Accreta: Diagnosis and Management: Green-top Guideline No. 27a.

Authors:  Erm Jauniaux; Z Alfirevic; A G Bhide; M A Belfort; G J Burton; S L Collins; S Dornan; D Jurkovic; G Kayem; J Kingdom; R Silver; L Sentilhes
Journal:  BJOG       Date:  2018-09-27       Impact factor: 6.531

3.  Trichosanthin, a Chinese medicine for the medical treatment of ectopic pregnancy with high levels of β-hCG.

Authors:  D J Xiang; L M Chen; J S Gu; P Stone; Qi Chen
Journal:  Reprod Sci       Date:  2012-01-19       Impact factor: 3.060

4.  The application of uterine wall local resection and reconstruction to preserve the uterus for the management of morbidly adherent placenta: Case series.

Authors:  Xianlan Zhao; Ya Tao; Yingying Du; Lei Zhao; Cai Liu; Yan Zhou; Peng Wei
Journal:  Taiwan J Obstet Gynecol       Date:  2018-04       Impact factor: 1.705

5.  FIGO consensus guidelines on placenta accreta spectrum disorders: Conservative management.

Authors:  Loïc Sentilhes; Gilles Kayem; Edwin Chandraharan; José Palacios-Jaraquemada; Eric Jauniaux
Journal:  Int J Gynaecol Obstet       Date:  2018-03       Impact factor: 3.561

6.  FIGO consensus guidelines on placenta accreta spectrum disorders: Prenatal diagnosis and screening.

Authors:  Eric Jauniaux; Amar Bhide; Anne Kennedy; Paula Woodward; Corrine Hubinont; Sally Collins
Journal:  Int J Gynaecol Obstet       Date:  2018-03       Impact factor: 3.561

7.  Leaving the placenta in situ versus conservative and radical surgery in the treatment of placenta accreta spectrum disorders.

Authors:  Mehmet S Kutuk; Mehmet Ak; Mahmut T Ozgun
Journal:  Int J Gynaecol Obstet       Date:  2017-09-18       Impact factor: 3.561

Review 8.  Surgical Management of Placenta Accreta Spectrum.

Authors:  Brett D Einerson; D Ware Branch
Journal:  Clin Obstet Gynecol       Date:  2018-12       Impact factor: 2.190

Review 9.  Management of Abnormal Placenta Implantation with Methotrexate: A Review of Published Data.

Authors:  Maryam Farasatinasab; Azadeh Moghaddas; Simin Dashti-Khadivaki; Zahra Raoofi; Somayyeh Nasiripour
Journal:  Gynecol Obstet Invest       Date:  2016-07-07       Impact factor: 2.031

Review 10.  Placenta Accreta Spectrum: A Review of Pathology, Molecular Biology, and Biomarkers.

Authors:  Helena C Bartels; James D Postle; Paul Downey; Donal J Brennan
Journal:  Dis Markers       Date:  2018-07-03       Impact factor: 3.434

  10 in total

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