BACKGROUND: Shuxuetong injection (SXT) is a Chinese medicine injection and has been widely used for the treatment of acute myocardial infarction (AMI) in Asia. However, whether SXT has a definite efficacy and safety is poorly understood. The aim of our study was to clarify the effect of SXT on clinical symptoms alliavation and survival in AMI patients. METHODS: A systematic reviews of SXT combined with conventional therapy treating AMI will be searched in 8 electronic databases including PubMed, Cochrane Library, Embase, Wanfang Database, China Biology Medicine (CBM), Google Scholar, Chinese Scientific Journal Database (VIP), and China National Knowledge Infrastructure (CNKI), from inception to December 2020. The literature will extracted by 2 researchers independently and the methodological quality of the included study will be evaluated. We will use the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system to evaluate the evidence quality of the included literature. RevMan software (version 5.3) will be applied for the original research data synthesis. RESULTS: The results of our study will be published in a peer reviewed journal. CONCLUSION: Our meta-analysis will provide the latest evidence to determine whether SXT is an effective intervention for AMI patients.
BACKGROUND: Shuxuetong injection (SXT) is a Chinese medicine injection and has been widely used for the treatment of acute myocardial infarction (AMI) in Asia. However, whether SXT has a definite efficacy and safety is poorly understood. The aim of our study was to clarify the effect of SXT on clinical symptoms alliavation and survival in AMI patients. METHODS: A systematic reviews of SXT combined with conventional therapy treating AMI will be searched in 8 electronic databases including PubMed, Cochrane Library, Embase, Wanfang Database, China Biology Medicine (CBM), Google Scholar, Chinese Scientific Journal Database (VIP), and China National Knowledge Infrastructure (CNKI), from inception to December 2020. The literature will extracted by 2 researchers independently and the methodological quality of the included study will be evaluated. We will use the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system to evaluate the evidence quality of the included literature. RevMan software (version 5.3) will be applied for the original research data synthesis. RESULTS: The results of our study will be published in a peer reviewed journal. CONCLUSION: Our meta-analysis will provide the latest evidence to determine whether SXT is an effective intervention for AMI patients.
Authors: Daniel S Menees; Eric D Peterson; Yongfei Wang; Jeptha P Curtis; John C Messenger; John S Rumsfeld; Hitinder S Gurm Journal: N Engl J Med Date: 2013-09-05 Impact factor: 91.245
Authors: Emelia J Benjamin; Michael J Blaha; Stephanie E Chiuve; Mary Cushman; Sandeep R Das; Rajat Deo; Sarah D de Ferranti; James Floyd; Myriam Fornage; Cathleen Gillespie; Carmen R Isasi; Monik C Jiménez; Lori Chaffin Jordan; Suzanne E Judd; Daniel Lackland; Judith H Lichtman; Lynda Lisabeth; Simin Liu; Chris T Longenecker; Rachel H Mackey; Kunihiro Matsushita; Dariush Mozaffarian; Michael E Mussolino; Khurram Nasir; Robert W Neumar; Latha Palaniappan; Dilip K Pandey; Ravi R Thiagarajan; Mathew J Reeves; Matthew Ritchey; Carlos J Rodriguez; Gregory A Roth; Wayne D Rosamond; Comilla Sasson; Amytis Towfighi; Connie W Tsao; Melanie B Turner; Salim S Virani; Jenifer H Voeks; Joshua Z Willey; John T Wilkins; Jason Hy Wu; Heather M Alger; Sally S Wong; Paul Muntner Journal: Circulation Date: 2017-01-25 Impact factor: 29.690
Authors: Sahil Khera; Dhaval Kolte; Tanush Gupta; Kathir Selvan Subramanian; Neel Khanna; Wilbert S Aronow; Chul Ahn; Robert J Timmermans; Howard A Cooper; Gregg C Fonarow; William H Frishman; Julio A Panza; Deepak L Bhatt Journal: J Am Coll Cardiol Date: 2015-11-03 Impact factor: 24.094
Authors: Min Chul Kim; Jae Yeong Cho; Hae Chang Jeong; Ki Hong Lee; Keun Ho Park; Doo Sun Sim; Nam Sik Yoon; Hyun Joo Yoon; Kye Hun Kim; Young Joon Hong; Hyung Wook Park; Ju Han Kim; Myung Ho Jeong; Jeong Gwan Cho; Jong Chun Park; Ki-Bae Seung; Kiyuk Chang; Youngkeun Ahn Journal: Am J Cardiol Date: 2014-10-12 Impact factor: 2.778
Authors: Kristian Thygesen; Joseph S Alpert; Allan S Jaffe; Bernard R Chaitman; Jeroen J Bax; David A Morrow; Harvey D White Journal: Eur Heart J Date: 2019-01-14 Impact factor: 29.983
Authors: Sheng-Chia Chung; Rolf Gedeborg; Owen Nicholas; Stefan James; Anders Jeppsson; Charles Wolfe; Peter Heuschmann; Lars Wallentin; John Deanfield; Adam Timmis; Tomas Jernberg; Harry Hemingway Journal: Lancet Date: 2014-01-23 Impact factor: 79.321