Evette Cordoba1,2, Angela M Parcesepe3,4, John A Gallis5,6, Jennifer Headley5, Claudian Soffo7, Berenger Tchatchou8, John Hembling9, Joy Noel Baumgartner5. 1. Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America. 2. School of Nursing, Columbia University, New York, New York, United States of America. 3. Department of Maternal and Child Health, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America. 4. Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America. 5. Duke Global Health Institute, Duke University, Durham, North Carolina, United States of America. 6. Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina, United States of America. 7. Consultant, Yaoundé, Cameroon. 8. Catholic Relief Services, N'Djamena, Chad. 9. Catholic Relief Services, Baltimore, Maryland, United States of America.
Abstract
BACKGROUND: This research advances understanding of interrelationships among three barriers to adherence to antiretroviral therapy (ART) among pregnant women living with HIV (WLWH) in Cameroon: probable common mental disorders (CMD), intimate partner violence (IPV), and hunger. METHODS: The sample included 220 pregnant WLWH in Cameroon. Multivariable modified Poisson regression was conducted to assess the relationship between IPV, hunger, and CMD on ART adherence. RESULTS: Almost half (44%) of participants recently missed/mistimed an ART dose. Probable CMD was associated with greater risk of missed/mistimed ART dose (aRR 1.5 [95% CI 1.1, 1.9]). Hunger was associated with greater risk of missed/mistimed ART dose among those who reported IPV (aRR 1.9 [95% CI 1.2, 2.8]), but not among those who did not (aRR 0.8 [95% CI 0.2, 2.3]). CONCLUSION: Suboptimal ART adherence, CMD, and IPV were common among pregnant WLWH in Cameroon. Pregnant WLWH experiencing IPV and hunger may be especially vulnerable to suboptimal ART adherence.
BACKGROUND: This research advances understanding of interrelationships among three barriers to adherence to antiretroviral therapy (ART) among pregnant women living with HIV (WLWH) in Cameroon: probable common mental disorders (CMD), intimate partner violence (IPV), and hunger. METHODS: The sample included 220 pregnant WLWH in Cameroon. Multivariable modified Poisson regression was conducted to assess the relationship between IPV, hunger, and CMD on ART adherence. RESULTS: Almost half (44%) of participants recently missed/mistimed an ART dose. Probable CMD was associated with greater risk of missed/mistimed ART dose (aRR 1.5 [95% CI 1.1, 1.9]). Hunger was associated with greater risk of missed/mistimed ART dose among those who reported IPV (aRR 1.9 [95% CI 1.2, 2.8]), but not among those who did not (aRR 0.8 [95% CI 0.2, 2.3]). CONCLUSION: Suboptimal ART adherence, CMD, and IPV were common among pregnant WLWH in Cameroon. Pregnant WLWH experiencing IPV and hunger may be especially vulnerable to suboptimal ART adherence.
Authors: Brandon A Knettel; Cody Cichowitz; James Samwel Ngocho; Elizabeth T Knippler; Lilian N Chumba; Blandina T Mmbaga; Melissa H Watt Journal: J Acquir Immune Defic Syndr Date: 2018-04-15 Impact factor: 3.731
Authors: Linda Richter; Mary Jane Rotheram-Borus; Alastair Van Heerden; Alan Stein; Mark Tomlinson; Jessica M Harwood; Tamsen Rochat; Heidi Van Rooyen; W Scott Comulada; Zihling Tang Journal: AIDS Behav Date: 2014-04