Literature DB >> 33603908

Evaluation of Medicine Exposure During Pregnancy at a Tertiary Center of an Indian State.

Manoj Kumar Saurabh1, Subodh Kumar1, Vikash Maharshi1.   

Abstract

Context: Prescribing drugs in pregnancy is a challenging approach for doctors. Objective:To evaluate drugs used in pregnancy. Method:A prospective, cross-sectional, descriptive study was carried out by collecting and evaluating prescriptions on various parameters.
Results: More than 50% of antenatal care attendees belonged to the 18-24 age group, and 102 (41.46%) were primigravidae. The main presenting complaints were abdominal pain (25.16%), followed by nausea and vomiting (22.60%) and fever (11.14%); the maximum number of visits to hospital was seen in the first trimester (40.53%), followed by the third trimester (38.42%). It was observed that 25.78% of prescriptions did not contain any medicine. The average number of prescribed medicines was 2.32, with the lowest in the first trimester (1.77) and the highest in the second trimester (2.78). It was noticed that 74.11% and 71.26% of all prescribed medicines were from essential medicine list and generics, respectively. Of all prescribed drugs, 11.52% were antimicrobials, and 4.11% injectable dosage forms. Vitamins and minerals were the preferred prescribed medicines (34.82%), followed by antimicrobial agents (11.52%) and doxylamine plus pyridoxine (10.16%). Also, doctors who made the drug choice during antenatal visits were more confident in evidence-based safety as per New Pregnancy and Lactation Rule (PPLR); 45.37% of drugs were prescribed from category A, followed by 38.25% from category B and none from group X.
Conclusion: Doctors were concerned about prescribing safer drugs in pregnancy and were more confident in evidence-based medication.

Entities:  

Year:  2020        PMID: 33603908      PMCID: PMC7879351          DOI: 10.26574/maedica.2020.15.4.503

Source DB:  PubMed          Journal:  Maedica (Bucur)        ISSN: 1841-9038


  12 in total

1.  FDA drug labeling for pregnancy and lactation drug safety monitoring systems.

Authors:  Michael F Greene
Journal:  Semin Perinatol       Date:  2015-10-01       Impact factor: 3.300

Review 2.  Clinical biochemistry of pregnancy.

Authors:  G Lockitch
Journal:  Crit Rev Clin Lab Sci       Date:  1997       Impact factor: 6.250

3.  Rationality of drug prescriptions in rural health centres in Burkina Faso.

Authors:  G Krause; M Borchert; J Benzler; R Heinmüller; I Kaba; M Savadogo; N Siho; H J Diesfeld
Journal:  Health Policy Plan       Date:  1999-09       Impact factor: 3.344

4.  Awareness of Mothers and Doctors about Drug Utilization Pattern for Illnesses Encountered during Pregnancy.

Authors:  Nargis Ibrahim Kureshee; Priti Pravin Dhande
Journal:  J Clin Diagn Res       Date:  2013-11-10

5.  Effects of vaginal progesterone on pain and uterine contractility in patients with threatened abortion before twelve weeks of pregnancy.

Authors:  A Palagiano; C Bulletti; M C Pace; D DE Ziegler; E Cicinelli; A Izzo
Journal:  Ann N Y Acad Sci       Date:  2004-12       Impact factor: 5.691

6.  A study of drug use during pregnancy in a teaching hospital in western Nepal.

Authors:  Biswadeep Das; Chayna Sarkar; Adrija Datta; Sangeeta Bohra
Journal:  Pharmacoepidemiol Drug Saf       Date:  2003 Apr-May       Impact factor: 2.890

7.  Drug utilization pattern during pregnancy in North India.

Authors:  Rashmi Sharma; Bhuvneshvar Kapoor; Ujala Verma
Journal:  Indian J Med Sci       Date:  2006-07

8.  Alcohol and Other Drug Use during Pregnancy among Women Attending Midwife Obstetric Units in the Cape Metropole, South Africa.

Authors:  Petal Petersen Williams; Esmé Jordaan; Catherine Mathews; Carl Lombard; Charles D H Parry
Journal:  Adv Prev Med       Date:  2014-02-03

9.  Drug utilization pattern among pregnant women attending maternal and child health clinic of tertiary hospital in eastern Ethiopia: Consideration of toxicological perspectives.

Authors:  Neim Bedewi; Mekonnen Sisay; Dumessa Edessa
Journal:  BMC Res Notes       Date:  2018-12-04

10.  The effect of progesterone suppositories on threatened abortion: a randomized clinical trial.

Authors:  Fakhrolmolouk Yassaee; Reza Shekarriz-Foumani; Shabnam Afsari; Masoumeh Fallahian
Journal:  J Reprod Infertil       Date:  2014-07
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