Literature DB >> 33603782

Clinical Analysis of Cervical Lymph Node Metastasis Risk Factors and the Feasibility of Prophylactic Central Lymph Node Dissection in Papillary Thyroid Carcinoma.

Yifan Chen1,2, Shuo Chen2,3, Xiaoying Lin1,2, Xiangqing Huang1,2, Xiaofang Yu1,4, Juying Chen1,2.   

Abstract

OBJECTIVE: To identify the risk factors for cervical lymph node metastasis (CLNM) and the feasibility of prophylactic central lymph node dissection.
METHODS: The characteristics of 1107 patients were extracted and analyzed. Univariate and multivariate analyses were used to identify risk factors associated with lymph node metastasis. The relationship between the central lymph node dissection (CLND) and lateral lymph node metastasis (LLNM) was analyzed using the correlation analysis.
RESULTS: The probability of CLNM was closely related to the male gender, age <55, and the increase of tumor size. Those patients with an increase in tumor size and CLNM were extremely prone to LLNM. Also, LLNM was more likely to happen in those with the more positive central lymph nodes. Routine prophylactic central lymph node dissection (P-CLND) did not increase the risk of complications.
CONCLUSION: P-CLND should be considered as a reasonable surgical treatment for PTC.
Copyright © 2021 Yifan Chen et al.

Entities:  

Year:  2021        PMID: 33603782      PMCID: PMC7868159          DOI: 10.1155/2021/6635686

Source DB:  PubMed          Journal:  Int J Endocrinol        ISSN: 1687-8337            Impact factor:   3.257


  54 in total

1.  Prophylactic central neck dissection and local recurrence in papillary thyroid cancer: a meta-analysis.

Authors:  Tarek Zetoune; Xavier Keutgen; Daniel Buitrago; Hasan Aldailami; Huibo Shao; Madhu Mazumdar; Thomas J Fahey; Rasa Zarnegar
Journal:  Ann Surg Oncol       Date:  2010-07-02       Impact factor: 5.344

2.  Role of prophylactic ipsilateral central compartment lymph node dissection in papillary thyroid microcarcinoma.

Authors:  Mujgan Caliskan; Jae Hyun Park; Jun Soo Jeong; Cho-Rok Lee; Seul Kee Park; Sang-Wook Kang; Jong Ju Jeong; Woong Youn Chung; Cheong Soo Park
Journal:  Endocr J       Date:  2012-01-12       Impact factor: 2.349

3.  Lymph node metastasis from 259 papillary thyroid microcarcinomas: frequency, pattern of occurrence and recurrence, and optimal strategy for neck dissection.

Authors:  Nobuyuki Wada; Quan-Yang Duh; Kiminori Sugino; Hiroyuki Iwasaki; Kaori Kameyama; Takashi Mimura; Koichi Ito; Hiroshi Takami; Yoshinori Takanashi
Journal:  Ann Surg       Date:  2003-03       Impact factor: 12.969

4.  Effect of reoperation on outcomes in papillary thyroid cancer.

Authors:  Stephanie Young; Avital Harari; Stephanie Smooke-Praw; Philip H G Ituarte; Michael W Yeh
Journal:  Surgery       Date:  2013-12       Impact factor: 3.982

5.  Preoperative staging of papillary thyroid carcinoma: comparison of ultrasound imaging and CT.

Authors:  Ji Soo Choi; Jinna Kim; Jin Young Kwak; Min Jung Kim; Hang Seok Chang; Eun-Kyung Kim
Journal:  AJR Am J Roentgenol       Date:  2009-09       Impact factor: 3.959

6.  Skip metastases in thyroid cancer leaping the central lymph node compartment.

Authors:  Andreas Machens; Hans-Jürgen Holzhausen; Henning Dralle
Journal:  Arch Surg       Date:  2004-01

7.  Three distinctly different kinds of papillary thyroid microcarcinoma should be recognized: our treatment strategies and outcomes.

Authors:  Iwao Sugitani; Kazuhisa Toda; Keiko Yamada; Noriko Yamamoto; Motoko Ikenaga; Yoshihide Fujimoto
Journal:  World J Surg       Date:  2010-06       Impact factor: 3.352

8.  Intrathyroidal differentiated thyroid carcinoma: tumor size-based surgical concepts.

Authors:  Paolo Miccoli; Michele N Minuto; Clara Ugolini; Erica Panicucci; Piero Berti; Marco Massi; Fulvio Basolo
Journal:  World J Surg       Date:  2007-05       Impact factor: 3.352

9.  Risk Factors for Cervical Lymph Node Metastasis of Papillary Thyroid Microcarcinoma: A Single-Center Retrospective Study.

Authors:  Feng Cheng; Yanyan Chen; Lei Zhu; Bin Zhou; Yonghong Xu; Yiran Chen; Liping Wen; Shuzheng Chen
Journal:  Int J Endocrinol       Date:  2019-01-15       Impact factor: 3.257

10.  Skip metastasis in papillary thyroid carcinoma is difficult to predict in clinical practice.

Authors:  Xilin Nie; Zhou Tan; Minghua Ge
Journal:  BMC Cancer       Date:  2017-10-25       Impact factor: 4.430

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  3 in total

1.  Predictors of impaired effectiveness of carbon nanoparticle-based central lymph node tracing in patients who underwent surgery for papillary thyroid cancer: A retrospective cohort study.

Authors:  Ping-Ping Chen; Xing Zhang; Jia-Gen Li; Gun Chen
Journal:  Medicine (Baltimore)       Date:  2022-10-14       Impact factor: 1.817

2.  Predictors and a Prediction Model for Central Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma (cN0).

Authors:  Xin Gao; Wenpei Luo; Lingyun He; Juan Cheng; Lu Yang
Journal:  Front Endocrinol (Lausanne)       Date:  2022-01-27       Impact factor: 5.555

3.  Value of dissection of lymph nodes posterior to the right recurrent laryngeal nerve in patients with cN0 papillary thyroid carcinoma.

Authors:  Xiangyuqin Xiao; Yaqin Wu; Lianhong Zou; Yiru Chen; Chaojie Zhang
Journal:  Gland Surg       Date:  2022-07
  3 in total

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