Literature DB >> 33603133

Efficacy of salt reduction for managing overactive bladder symptoms: a prospective study in patients with excessive daily salt intake.

Tomohiro Matsuo1, Yasuyoshi Miyata2, Asato Otsubo1, Yuta Mukae1, Kensuke Mitsunari1, Kojiro Ohba1, Hideki Sakai1.   

Abstract

This study aimed to investigate the efficacy of salt intake restriction on overactive bladder (OAB) symptoms in patients with excessive salt intake. Patients received a brochure on nutritional guidance regarding salt intake reduction and received health education every 4 weeks for 12 weeks. Data from overactive bladder symptom score (OABSS) questionnaires and frequency volume charts (FVCs) were evaluated. The daily salt intake was estimated by determining the urinary sodium and creatinine concentrations using spot urine samples. Of the 98 patients included, 71 (72.4%) successfully restricted their daily salt intake after 12 weeks (salt restricted [R] group), while 27 (27.6%) did not (salt non-restricted [N-R] group). The scores to each OABSS question and the resulting total score improved significantly in the R group; however, the individual scores remained unchanged and the total score increased in the N-R group. The FVC data indicated improved voided volumes in the R group as compared to in the N-R group. Ultimately, 17 (23.9%) patients in the R group no longer fulfilled the OAB diagnostic criteria after salt intake reduction. Thus, salt intake reduction improved urinary symptoms in patients with OAB and may be a therapeutic option for OAB in patients with excessive daily salt intakes.

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Year:  2021        PMID: 33603133      PMCID: PMC7893030          DOI: 10.1038/s41598-021-83725-9

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  34 in total

Review 1.  Mineralocorticoid receptors, salt-sensitive hypertension, and metabolic syndrome.

Authors:  Toshiro Fujita
Journal:  Hypertension       Date:  2010-02-22       Impact factor: 10.190

Review 2.  Vasodysfunction That Involves Renal Vasodysfunction, Not Abnormally Increased Renal Retention of Sodium, Accounts for the Initiation of Salt-Induced Hypertension.

Authors:  R Curtis Morris; Olga Schmidlin; Anthony Sebastian; Masae Tanaka; Theodore W Kurtz
Journal:  Circulation       Date:  2016-03-01       Impact factor: 29.690

3.  How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study.

Authors:  I Milsom; P Abrams; L Cardozo; R G Roberts; J Thüroff; A J Wein
Journal:  BJU Int       Date:  2001-06       Impact factor: 5.588

4.  Effect of dietary habits on the risk of metabolic syndrome: Yazd Healthy Heart Project.

Authors:  Mohammadtaghi Sarebanhassanabadi; Seyed Jalil Mirhosseini; Masoud Mirzaei; Seyedeh Mahdieh Namayandeh; Mohammad Hossein Soltani; Mohammadreza Pakseresht; Ali Pedarzadeh; Zahra Baramesipour; Reza Faraji; Amin Salehi-Abargouei
Journal:  Public Health Nutr       Date:  2017-12-13       Impact factor: 4.022

5.  Symptom assessment tool for overactive bladder syndrome--overactive bladder symptom score.

Authors:  Yukio Homma; Masaki Yoshida; Narihito Seki; Osamu Yokoyama; Hidehiro Kakizaki; Momokazu Gotoh; Tomonori Yamanishi; Osamu Yamaguchi; Masayuki Takeda; Osamu Nishizawa
Journal:  Urology       Date:  2006-08       Impact factor: 2.649

6.  Effect of salt intake reduction on nocturia in patients with excessive salt intake.

Authors:  Tomohiro Matsuo; Yasuyoshi Miyata; Hideki Sakai
Journal:  Neurourol Urodyn       Date:  2019-02-01       Impact factor: 2.696

7.  How should patients with an overactive bladder manipulate their fluid intake?

Authors:  Hashim Hashim; Paul Abrams
Journal:  BJU Int       Date:  2008-02-18       Impact factor: 5.588

8.  Results of a randomized phase III trial of mirabegron in patients with overactive bladder.

Authors:  Victor W Nitti; Stephen Auerbach; Nancy Martin; Alaina Calhoun; Misun Lee; Sender Herschorn
Journal:  J Urol       Date:  2012-10-16       Impact factor: 7.450

Review 9.  The effects of antimuscarinic treatments in overactive bladder: an update of a systematic review and meta-analysis.

Authors:  Christopher R Chapple; Vik Khullar; Zahava Gabriel; Dominic Muston; Caty Ebel Bitoun; David Weinstein
Journal:  Eur Urol       Date:  2008-06-20       Impact factor: 20.096

10.  Prevalence and burden of overactive bladder in the United States.

Authors:  W F Stewart; J B Van Rooyen; G W Cundiff; P Abrams; A R Herzog; R Corey; T L Hunt; A J Wein
Journal:  World J Urol       Date:  2002-11-15       Impact factor: 4.226

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