Literature DB >> 33602111

A Review on Hematopoietic Stem Cell Treatment for Epilepsy.

Mohan Krishna Ghanta1, Neha Merchant2, Lakkakula V K S Bhaskar3.   

Abstract

Epilepsy responds to pharmacotherapy in its initial stages. The response of some forms of epilepsy, like the refractory epilepsy, is extremely low. Surgical management of epilepsy is associated with complications, which necessitates the search for novel and modern strategies for the treatment of epilepsy. Neuroprotection and neuronal regeneration are the major targets that must be accomplished by the new strategies. Hematopoietic Stem Cell (HSCs) therapy for epilepsy has shown promising results in pre-clinical studies with marginal clinical effects. This review explores the characteristics, mechanism of action, and clinical significance of HSCs therapy for the treatment of epilepsy. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

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Keywords:  Neuroprotection; antiepileptic property; epilepsy; hematopoietic stem cell treatment; neuronal regeneration; seizure.

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Year:  2021        PMID: 33602111     DOI: 10.2174/1871527320666210218085816

Source DB:  PubMed          Journal:  CNS Neurol Disord Drug Targets        ISSN: 1871-5273            Impact factor:   4.388


  1 in total

1.  Simultaneous Determination of Lamotrigine, Oxcarbazepine, Lacosamide, and Topiramate in Rat Plasma by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry.

Authors:  Erjie Qiu; Lu Yu; Qishun Liang; Congcong Wen
Journal:  Int J Anal Chem       Date:  2022-03-14       Impact factor: 1.885

  1 in total

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