Literature DB >> 3360152

Amplification and over-expression of the neu oncogene in human breast carcinomas.

M J van de Vijver1, W J Mooi, J L Peterse, R Nusse.   

Abstract

Amplification of the neu (or c-erbB-2 or HER) oncogene is found to be present in 15-30% of human breast carcinomas and has been reported to correlate with poor prognosis. We briefly review the literature on this subject with emphasis on our own results on immunohistochemical detection of neu overproduction in paraffin embedded tissue sections of human breast carcinomas.

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Year:  1988        PMID： 3360152

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN： 0748-7983            Impact factor:   4.424


  8 in total

1.  p185, an immunodominant epitope, is an autoantigen mimotope.

Authors:  Sanjeev Kumar; John A Hinks; Joseph Maman; Chelliah T Ravirajan; Laurence H Pearl; David A Isenberg
Journal:  J Biol Chem       Date:  2011-05-12       Impact factor: 5.157

2.  Genomic alterations of the c-myc protooncogene in relation to the overexpression of c-erbB2 and Ki-67 in human breast and cervix carcinomas.

Authors:  P Münzel; D Marx; H Köchel; A Schauer; K W Bock
Journal:  J Cancer Res Clin Oncol       Date:  1991       Impact factor: 4.553

3.  Oncogenes and human breast cancer.

Authors:  J M Hall; P J Zuppan; L A Anderson; B Huey; C Carter; M C King
Journal:  Am J Hum Genet       Date:  1989-04       Impact factor: 11.025

4.  Prognostic value of c-erbB-2 expression in uterine cervical carcinoma.

Authors:  R J Hale; C H Buckley; H Fox; J Williams
Journal:  J Clin Pathol       Date:  1992-07       Impact factor: 3.411

5.  The prognostic value of c-erbB2 in primary breast carcinomas: a study on 942 cases.

Authors:  N Quénel; J Wafflart; F Bonichon; I de Mascarel; M Trojani; M Durand; A Avril; J M Coindre
Journal:  Breast Cancer Res Treat       Date:  1995-09       Impact factor: 4.872

6.  c-erbB2 expression in correlation to other biological parameters of breast cancer.

Authors:  D Marx; A Schauer; C Reiche; A May; L Ummenhofer; A Reles; H Rauschecker; R Sauer; M Schumacher
Journal:  J Cancer Res Clin Oncol       Date:  1990       Impact factor: 4.553

7.  c-erbB-2 oncoprotein expression in primary and advanced breast cancer.

Authors:  C Lovekin; I O Ellis; A Locker; J F Robertson; J Bell; R Nicholson; W J Gullick; C W Elston; R W Blamey
Journal:  Br J Cancer       Date:  1991-03       Impact factor: 7.640

8.  Can biomarker assessment on circulating tumor cells help direct therapy in metastatic breast cancer?

Authors:  Natalie Turner; Marta Pestrin; Francesca Galardi; Francesca De Luca; Luca Malorni; Angelo Di Leo
Journal:  Cancers (Basel)       Date:  2014-03-25       Impact factor: 6.639
  8 in total

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