Literature DB >> 33599783

[Less is more… in the general practitioner's internistic surgery : Subclinical hypothyroidism, hyperuricemia, routine ECG and NT-proBNP as selected examples].

M Schorrlepp1, D Burchert2.   

Abstract

Exceeding the need for care in general practitioner (GP) practices is a known problem that affects the work of approximately 16,000 specialists for internal medicine in the family practice context every day in Germany. In order to spare patients unnecessary treatment and measures, these must be critically questioned on a regular basis. Subclinical hypothyroidism (SH) and hyperuricemia (HU) are frequent laboratory constellations. The selected articles by Stott et al., de Montmollin et al. and Mooijaart et al. could show that treatment of SH in older patients is not effective. Furthermore, according to the studies of Li et al. and Badve et al. treatment of HU is only beneficial in the treatment of gout and nephrolithiasis and has no influence on the development of chronic kidney disease. The Canadian group of Bhatia demonstrated that the ECG for low-risk patients that is often part of health check-ups in Canada, usually results in more follow-up examinations without the groups with and without ECG differing with respect to major adverse cardiac events (MACE). Laboratory chemical analysis of N‑terminal prohormone of brain natriuretic peptide (NT-proBNP) for managing the treatment of heart failure is also not more effective than traditional treatment methods according to Felker et al., therefore, it can be discarded. "Choosing wisely", "Less is more" and the "Klug entscheiden (Smart decisions)" recommendations by the German Society for Internal Medicine are initiatives that make the process of avoiding overprovision of care accessible for all practitioners in a short and concise form.

Entities:  

Keywords:  Brain natriuretic peptide; Electrocardiography; Hyperuricemia; Medical overuse; Subclinical hypothyroidism

Mesh:

Substances:

Year:  2021        PMID: 33599783     DOI: 10.1007/s00108-021-00956-8

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  7 in total

1.  Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism.

Authors:  David J Stott; Nicolas Rodondi; Patricia M Kearney; Ian Ford; Rudi G J Westendorp; Simon P Mooijaart; Naveed Sattar; Carole E Aubert; Drahomir Aujesky; Douglas C Bauer; Christine Baumgartner; Manuel R Blum; John P Browne; Stephen Byrne; Tinh-Hai Collet; Olaf M Dekkers; Wendy P J den Elzen; Robert S Du Puy; Graham Ellis; Martin Feller; Carmen Floriani; Kirsty Hendry; Caroline Hurley; J Wouter Jukema; Sharon Kean; Maria Kelly; Danielle Krebs; Peter Langhorne; Gemma McCarthy; Vera McCarthy; Alex McConnachie; Mairi McDade; Martina Messow; Annemarie O'Flynn; David O'Riordan; Rosalinde K E Poortvliet; Terence J Quinn; Audrey Russell; Carol Sinnott; Jan W A Smit; H Anette Van Dorland; Kieran A Walsh; Elaine K Walsh; Torquil Watt; Robbie Wilson; Jacobijn Gussekloo
Journal:  N Engl J Med       Date:  2017-04-03       Impact factor: 91.245

2.  L-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial.

Authors:  Maria de Montmollin; Martin Feller; Shanthi Beglinger; Alex McConnachie; Drahomir Aujesky; Tinh-Hai Collet; Ian Ford; Jacobijn Gussekloo; Patricia M Kearney; Vera J C McCarthy; Simon Mooijaart; Rosalinde K E Poortvliet; Terence Quinn; David J Stott; Torquil Watt; Rudi Westendorp; Nicolas Rodondi; Douglas C Bauer
Journal:  Ann Intern Med       Date:  2020-05-05       Impact factor: 25.391

3.  Effect of Natriuretic Peptide-Guided Therapy on Hospitalization or Cardiovascular Mortality in High-Risk Patients With Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.

Authors:  G Michael Felker; Kevin J Anstrom; Kirkwood F Adams; Justin A Ezekowitz; Mona Fiuzat; Nancy Houston-Miller; James L Januzzi; Daniel B Mark; Ileana L Piña; Gayle Passmore; David J Whellan; Hongqiu Yang; Lawton S Cooper; Eric S Leifer; Patrice Desvigne-Nickens; Christopher M O'Connor
Journal:  JAMA       Date:  2017-08-22       Impact factor: 56.272

4.  Electrocardiograms in Low-Risk Patients Undergoing an Annual Health Examination.

Authors:  R Sacha Bhatia; Zachary Bouck; Noah M Ivers; Graham Mecredy; Jasjit Singh; Ciara Pendrith; Dennis T Ko; Danielle Martin; Harindra C Wijeysundera; Jack V Tu; Lynn Wilson; Kimberly Wintemute; Paul Dorian; Joshua Tepper; Peter C Austin; Richard H Glazier; Wendy Levinson
Journal:  JAMA Intern Med       Date:  2017-09-01       Impact factor: 21.873

5.  Effects of Allopurinol on the Progression of Chronic Kidney Disease.

Authors:  Sunil V Badve; Elaine M Pascoe; Anushree Tiku; Neil Boudville; Fiona G Brown; Alan Cass; Philip Clarke; Nicola Dalbeth; Richard O Day; Janak R de Zoysa; Bettina Douglas; Randall Faull; David C Harris; Carmel M Hawley; Graham R D Jones; John Kanellis; Suetonia C Palmer; Vlado Perkovic; Gopala K Rangan; Donna Reidlinger; Laura Robison; Robert J Walker; Giles Walters; David W Johnson
Journal:  N Engl J Med       Date:  2020-06-25       Impact factor: 91.245

6.  Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline.

Authors:  G E Bekkering; T Agoritsas; L Lytvyn; A F Heen; M Feller; E Moutzouri; H Abdulazeem; B Aertgeerts; D Beecher; J P Brito; P D Farhoumand; N Singh Ospina; N Rodondi; M van Driel; E Wallace; M Snel; P M Okwen; R Siemieniuk; P O Vandvik; T Kuijpers; M Vermandere
Journal:  BMJ       Date:  2019-05-14

Review 7.  Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studies.

Authors:  Xue Li; Xiangrui Meng; Maria Timofeeva; Ioanna Tzoulaki; Konstantinos K Tsilidis; John PA Ioannidis; Harry Campbell; Evropi Theodoratou
Journal:  BMJ       Date:  2017-06-07
  7 in total

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