Literature DB >> 33599780

Contrast-enhanced ultrasound of the pediatric brain.

Misun Hwang1,2, Carol E Barnewolt3, Jörg Jüngert4, Francesco Prada5,6,7, Anush Sridharan8, Ryne A Didier8,9.   

Abstract

Brain contrast-enhanced ultrasound (CEUS) is an emerging application that can complement gray-scale US and yield additional insights into cerebral flow dynamics. CEUS uses intravenous injection of ultrasound contrast agents (UCAs) to highlight tissue perfusion and thus more clearly delineate cerebral pathologies including stroke, hypoxic-ischemic injury and focal lesions such as tumors and vascular malformations. It can be applied not only in infants with open fontanelles but also in older children and adults via a transtemporal window or surgically created acoustic window. Advancements in CEUS technology and post-processing methods for quantitative analysis of UCA kinetics further elucidate cerebral microcirculation. In this review article we discuss the CEUS examination protocol for brain imaging in children, current clinical applications and future directions for research and clinical uses of brain CEUS.
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.

Entities:  

Keywords:  Brain; Children; Contrast-enhanced ultrasound; Epilepsy; Hypoxic–ischemic injury; Neurovascular disease; Stroke; Tumor; Ultrasound; Ultrasound contrast agents

Mesh：

Substances：

Year:  2021        PMID： 33599780     DOI： 10.1007/s00247-021-04974-4

Source DB:  PubMed          Journal:  Pediatr Radiol        ISSN： 0301-0449


  106 in total

1.  Transcranial ultrasound brain perfusion assessment with a contrast agent-specific imaging mode: results of a two-center trial.

Authors:  Thilo Hölscher; Wilko Wilkening; Bogdan Draganski; Saskia H Meves; Jens Eyding; Heinz Voit; Ulrich Bogdahn; Horst Przuntek; Thomas Postert
Journal:  Stroke       Date:  2005-09-01       Impact factor: 7.914

2.  Diagnostic transcranial ultrasound perfusion-imaging at 2.5 MHz does not affect the blood-brain barrier.

Authors:  Gerhard J Jungehulsing; Peter Brunecker; Christian H Nolte; Jochen B Fiebach; Claudia Kunze; Florian Doepp; Arno Villringer; Stephan J Schreiber
Journal:  Ultrasound Med Biol       Date:  2007-09-14       Impact factor: 2.998

3.  Novel Quantitative Contrast-Enhanced Ultrasound Detection of Hypoxic Ischemic Injury in Neonates and Infants: Pilot Study 1.

Authors:  Misun Hwang; Anush Sridharan; Kassa Darge; Becky Riggs; Chandra Sehgal; John Flibotte; Thierry A G M Huisman
Journal:  J Ultrasound Med       Date:  2018-12-17       Impact factor: 2.153

4.  Identification of residual tumor with intraoperative contrast-enhanced ultrasound during glioblastoma resection.

Authors:  Francesco Prada; Massimiliano Del Bene; Riccardo Fornaro; Ignazio G Vetrano; Alberto Martegani; Luca Aiani; Luca Maria Sconfienza; Giovanni Mauri; Luigi Solbiati; Bianca Pollo; Francesco DiMeco
Journal:  Neurosurg Focus       Date:  2016-03       Impact factor: 4.047

5.  Diagnostic impact of cerebral transit time in the identification of microangiopathy in dementia: A transcranial ultrasound study.

Authors:  I Puls; K Hauck; K Demuth; A Horowski; M Schliesser; P Dörfler; P Scheel; K V Toyka; K Reiners; M Schöning; G Becker
Journal:  Stroke       Date:  1999-11       Impact factor: 7.914

Review 6.  Potential of Contrast-Enhanced Ultrasound as a Bedside Monitoring Technique in Cerebral Perfusion: a Systematic Review.

Authors:  Elisabeth J Vinke; Anna J Kortenbout; Jens Eyding; Cornelis H Slump; Johannes G van der Hoeven; Chris L de Korte; Cornelia W E Hoedemaekers
Journal:  Ultrasound Med Biol       Date:  2017-09-28       Impact factor: 2.998

7.  Real-time ultrasound brain perfusion imaging with analysis of microbubble replenishment in acute MCA stroke.

Authors:  Rolf Kern; Anna Diels; Johanna Pettenpohl; Micha Kablau; Joachim Brade; Michael G Hennerici; Stephen Meairs
Journal:  J Cereb Blood Flow Metab       Date:  2011-03-02       Impact factor: 6.200

Review 8.  Introduction to contrast-enhanced ultrasound of the brain in neonates and infants: current understanding and future potential.

Authors:  Misun Hwang
Journal:  Pediatr Radiol       Date:  2018-10-23

9.  Comparison between echo contrast agent-specific imaging modes and perfusion-weighted magnetic resonance imaging for the assessment of brain perfusion.

Authors:  Saskia H Meves; Wilko Wilkening; Tammo Thies; Jens Eyding; Thilo Hölscher; Michael Finger; Gebhard Schmid; Helmut Ermert; Thomas Postert
Journal:  Stroke       Date:  2002-10       Impact factor: 7.914

10.  Cerebral artery Doppler ultrasonography for prediction of outcome after perinatal asphyxia.

Authors:  L N Archer; M I Levene; D H Evans
Journal:  Lancet       Date:  1986-11-15       Impact factor: 79.321
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  5 in total

1.  A concise guide to transtemporal contrast-enhanced ultrasound in children.

Authors:  Misun Hwang; Luis Octavio Tierradentro-Garcia
Journal:  J Ultrasound       Date:  2022-05-14

2.  Transtemporal brain contrast-enhanced ultrasound in children: preliminary experience in patients without neurological disorders.

Authors:  Luis Octavio Tierradentro-García; Anush Sridharan; Misun Hwang
Journal:  J Ultrasound       Date:  2022-08-27

3.  Intracranial Pressure and Cerebral Hemodynamic Monitoring After Cardiac Arrest in Pediatric Pigs Using Contrast Ultrasound-Derived Parameters.

Authors:  Samuel S Shin; Anush Sridharan; Kristina Khaw; Thomas Hallowell; Ryan W Morgan; Todd J Kilbaugh; Misun Hwang
Journal:  J Ultrasound Med       Date:  2021-09-15       Impact factor: 2.754

Review 4.  Advanced Ultrasound Techniques for Neuroimaging in Pediatric Critical Care: A Review.

Authors:  Colbey W Freeman; Misun Hwang
Journal:  Children (Basel)       Date:  2022-01-30

5.  Brain contrast-enhanced ultrasonography and elastography in infants.

Authors:  Misun Hwang; Zeng Zhang; Joseph Katz; Colbey Freeman; Todd Kilbaugh
Journal:  Ultrasonography       Date:  2022-03-30
  5 in total

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