Nada Qaisar Qureshi1, Syed Hamza Mufarrih1, Gerald S Bloomfield2,3,4, Wajeeha Tariq1, Aysha Almas1, Ali H Mokdad5, John Bartlett4, Imran Nisar6, Sameen Siddiqi7, Zulfiqar Bhutta8,9,10, Daniel Mark3, Pamela S Douglas3, Zainab Samad1,2. 1. Department of Medicine, The Aga Khan University, Karachi, PK. 2. Division of Cardiology, Department of Medicine, Duke University, Durham, NC, US. 3. Duke Clinical Research Institute, Duke University, Durham, NC, US. 4. Duke Global Health Institute, Duke University, Durham, NC, US. 5. Department of Health Metrics Sciences, University of Washington, Seattle, WA, US. 6. Department of Pediatrics and Child Health, The Aga Khan University, Karachi, PK. 7. Department of Community Health Sciences, The Aga Khan University, Karachi PK. 8. Centre of Excellence in Women and Child Health, Aga Khan University, Karachi, PK. 9. Centre for Global Child Health, The Hospital for Sick Children, Toronto, ON, CA. 10. University of Toronto, Toronto, ON, CA.
Abstract
Background: Cardiovascular disease (CVD) is the leading cause of death and disability worldwide. Health research is crucial to managing disease burden. Previous work has highlighted marked discrepancies in research output and disease burden between high-income countries (HICs) and low- and lower-middle-income countries (LI-LMICs) and there is little data to understand whether this gap has bridged in recent years. We conducted a global, country level bibliometric analysis of CVD publications with respect to trends in disease burden and county development indicators. Methods: A search filter with a precision and recall of 0.92 and 0.91 respectively was developed to extract cardiovascular publications from the Web of Science (WOS) for the years 2008-2017. Data for disease burden and country development indicators were extracted from the Global Burden of Disease and the World Bank database respectively. Results: Our search revealed 847,708 CVD publications for the period 2008-17, with a 43.4% increase over the decade. HICs contributed 81.1% of the global CVD research output and accounted for 8.1% and 8.5% of global CVD DALY losses deaths respectively. LI-LMICs contributed 2.8% of the total output and accounted for 59.5% and 57.1% global CVD DALY losses and death rates. Conclusions: A glaring disparity in research output and disease burden persists. While LI-LMICs contribute to the majority of DALYs and mortality from CVD globally, their contribution to research output remains the lowest. These data call on national health budgets and international funding support to allocate funds to strengthen research capacity and translational research to impact CVD burden in LI-LMICs. Copyright:
Background: Cardiovascular disease (CVD) is the leading cause of death and disability worldwide. Health research is crucial to managing disease burden. Previous work has highlighted marked discrepancies in research output and disease burden between high-income countries (HICs) and low- and lower-middle-income countries (LI-LMICs) and there is little data to understand whether this gap has bridged in recent years. We conducted a global, country level bibliometric analysis of CVD publications with respect to trends in disease burden and county development indicators. Methods: A search filter with a precision and recall of 0.92 and 0.91 respectively was developed to extract cardiovascular publications from the Web of Science (WOS) for the years 2008-2017. Data for disease burden and country development indicators were extracted from the Global Burden of Disease and the World Bank database respectively. Results: Our search revealed 847,708 CVD publications for the period 2008-17, with a 43.4% increase over the decade. HICs contributed 81.1% of the global CVD research output and accounted for 8.1% and 8.5% of global CVD DALY losses deaths respectively. LI-LMICs contributed 2.8% of the total output and accounted for 59.5% and 57.1% global CVD DALY losses and death rates. Conclusions: A glaring disparity in research output and disease burden persists. While LI-LMICs contribute to the majority of DALYs and mortality from CVD globally, their contribution to research output remains the lowest. These data call on national health budgets and international funding support to allocate funds to strengthen research capacity and translational research to impact CVD burden in LI-LMICs. Copyright:
Authors: Manuel Urina-Jassir; Maria Alejandra Jaimes-Reyes; Samuel Martinez-Vernaza; Miguel Urina-Triana Journal: Braz J Cardiovasc Surg Date: 2022-05-23
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