Literature DB >> 33596878

Pelvic organ prolapse and uterine preservation: a cohort study (POP-UP study).

Daniel Gagyor1, Vladimir Kalis2,3, Martin Smazinka3, Zdenek Rusavy2,3, Radovan Pilka1, Khaled M Ismail4,5.   

Abstract

BACKGROUND: Abdominal and laparoscopic sacro-colpopexy (LSC) is considered the standard surgical option for the management of a symptomatic apical pelvic organ prolapse (POP). Women who have their uterus, and for whom an LSC is indicated, can have a laparoscopic sacro-hysteropexy (LSH), a laparoscopic supra-cervical hysterectomy and laparoscopic sacro-cervicopexy (LSCH + LSC) or a total laparoscopic hysterectomy and laparoscopic sacro-colpopexy (TLH + LSC). The main aim of this study was to compare clinical and patient reported outcomes of uterine sparing versus concomitant hysterectomy LSC procedures.
METHODS: A retrospective analysis of clinical, imaging and patient reported outcomes at baseline, 3 and 12 months after LSH versus either LSCH + LSC or TLH + LSC between January 2015 and January 2019 in a tertiary referral urogynecology center in Pilsen, the Czech Republic.
RESULTS: In total, 294 women were included in this analysis (LSH n = 43, LSCH + LSC n = 208 and TLH + LSC n = 43). There were no differences in the incidence of perioperative injuries and complications. There were no statistically significant differences between the concomitant hysterectomy and the uterine sparing groups in any of the operative, clinical or patient reported outcomes except for a significantly lower anterior compartment failure rate (p = 0.017) and higher optimal mesh placement rate at 12 months in women who had concomitant hysterectomy procedures (p = 0.006).
CONCLUSION: LSH seems to be associated with higher incidence of anterior compartment failures and suboptimal mesh placement based on postoperative imaging techniques compared to LSC with concomitant hysterectomy.

Entities:  

Keywords:  Cervicopexy; Compartment; Hysteropexy; LSC; LSCH + LSC; LSH; Laparoscopic; Mesh; PFDI; PGI-I; POP-Q; Sacrocolpopexy; TLH + LSC

Mesh:

Year:  2021        PMID: 33596878      PMCID: PMC7890869          DOI: 10.1186/s12905-021-01208-5

Source DB:  PubMed          Journal:  BMC Womens Health        ISSN: 1472-6874            Impact factor:   2.809


  40 in total

1.  A case of renal dysfunction caused by pelvic organ prolapse.

Authors:  Ai Miyagi; Yusuke Inaguma; Tomoaki Tokoyoda; Takashi Nakajima; Ryozo Sezaki; Tetsuya Matsukawa
Journal:  CEN Case Rep       Date:  2017-06-20

2.  Laparoscopic sacral hysteropexy versus laparoscopic sacrocolpopexy with hysterectomy for pelvic organ prolapse.

Authors:  Ke Pan; Lili Cao; Nicholas A Ryan; Yanzhou Wang; Huicheng Xu
Journal:  Int Urogynecol J       Date:  2015-07-16       Impact factor: 2.894

3.  An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic organ prolapse (POP).

Authors:  Bernard T Haylen; Christopher F Maher; Matthew D Barber; Sérgio Camargo; Vani Dandolu; Alex Digesu; Howard B Goldman; Martin Huser; Alfredo L Milani; Paul A Moran; Gabriel N Schaer; Mariëlla I J Withagen
Journal:  Int Urogynecol J       Date:  2016-04       Impact factor: 2.894

4.  Pelvic Organ Prolapse Recurrence and Patient-Centered Outcomes Following Minimally Invasive Abdominal Uterosacral Ligament and Mesh-Augmented Sacrohysteropexy.

Authors:  Emily R W Davidson; Viviana Casas-Puig; Marie Fidela R Paraiso; Beri Ridgeway; Cecile A Ferrando
Journal:  Female Pelvic Med Reconstr Surg       Date:  2020-12-01       Impact factor: 2.091

5.  Psychometric evaluation of 2 comprehensive condition-specific quality of life instruments for women with pelvic floor disorders.

Authors:  M D Barber; M N Kuchibhatla; C F Pieper; R C Bump
Journal:  Am J Obstet Gynecol       Date:  2001-12       Impact factor: 8.661

6.  Laparoscopic sacrohysteropexy: the Pilsner modification.

Authors:  Vladimir Kalis; Zdenek Rusavy; Khaled M Ismail
Journal:  Int Urogynecol J       Date:  2019-12-04       Impact factor: 2.894

7.  Renal failure caused by severe pelvic organ prolapse.

Authors:  Eliane A Lucassen; Claire F la Chapelle; Esmee Krouwel; Marc Groeneveld
Journal:  BMJ Case Rep       Date:  2019-07-16

8.  Validation of the Patient Global Impression of Improvement (PGI-I) for urogenital prolapse.

Authors:  Sushma Srikrishna; Dudley Robinson; Linda Cardozo
Journal:  Int Urogynecol J       Date:  2009-12-15       Impact factor: 2.894

9.  Prevalence and trends of symptomatic pelvic floor disorders in U.S. women.

Authors:  Jennifer M Wu; Camille P Vaughan; Patricia S Goode; David T Redden; Kathryn L Burgio; Holly E Richter; Alayne D Markland
Journal:  Obstet Gynecol       Date:  2014-01       Impact factor: 7.661

10.  Prevalence and risk factors for mesh erosion after laparoscopic-assisted sacrocolpopexy.

Authors:  Jasmine Tan-Kim; Shawn A Menefee; Karl M Luber; Charles W Nager; Emily S Lukacz
Journal:  Int Urogynecol J       Date:  2010-09-15       Impact factor: 2.894

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  1 in total

Review 1.  Role of Hysteropexy in the Management of Pelvic Organ Prolapse.

Authors:  Zoe S Gan; Daniel S Roberson; Ariana L Smith
Journal:  Curr Urol Rep       Date:  2022-07-05       Impact factor: 2.862

  1 in total

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